Published in J Neuropathol Exp Neurol on January 01, 2015
Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals. J Cereb Blood Flow Metab (2016) 0.88
Brain pathologies in extreme old age. Neurobiol Aging (2015) 0.84
ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target. Ageing Res Rev (2015) 0.81
Hippocampal Sclerosis of Aging Can Be Segmental: Two Cases and Review of the Literature. J Neuropathol Exp Neurol (2015) 0.80
What we know about TMEM106B in neurodegeneration. Acta Neuropathol (2016) 0.79
Hippocampal Sclerosis of Aging, a Common Alzheimer's Disease 'Mimic': Risk Genotypes are Associated with Brain Atrophy Outside the Temporal Lobe. J Alzheimers Dis (2016) 0.76
Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging. Acta Neuropathol (2016) 0.76
Novel human ABCC9/SUR2 brain-expressed transcripts and an eQTL relevant to hippocampal sclerosis of aging. J Neurochem (2015) 0.76
Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2. Neurobiol Aging (2017) 0.75
Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle. NPJ Aging Mech Dis (2015) 0.75
Noncoding RNAs in neurodegeneration. Nat Rev Neurosci (2017) 0.75
Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice. Neuron (2017) 0.75
"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res (1975) 301.74
Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (1991) 49.03
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science (2006) 27.96
Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology (2005) 21.67
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol Aging (1995) 6.86
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathol (2011) 6.00
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann Neurol (2007) 5.98
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
The National Alzheimer's Coordinating Center (NACC) database: the Uniform Data Set. Alzheimer Dis Assoc Disord (2007) 5.01
Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann Neurol (2007) 4.47
A harmonized classification system for FTLD-TDP pathology. Acta Neuropathol (2011) 4.15
Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. Neuron (2010) 3.44
The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: a commentary. Neurobiol Aging (1997) 2.72
The neuropathology of older persons with and without dementia from community versus clinic cohorts. J Alzheimers Dis (2009) 2.54
Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia. Hum Mol Genet (2008) 2.48
Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons. Brain Pathol (2008) 2.44
Hippocampal sclerosis: a common pathological feature of dementia in very old (> or = 80 years of age) humans. Acta Neuropathol (1994) 2.23
Hippocampal sclerosis in advanced age: clinical and pathological features. Brain (2011) 2.16
Frontotemporal dementia and its subtypes: a genome-wide association study. Lancet Neurol (2014) 1.88
Low sensitivity in clinical diagnoses of dementia with Lewy bodies. J Neurol (2009) 1.73
The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum. Ann Med (2012) 1.66
Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study. Arch Neurol (2002) 1.65
Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies. Acta Neuropathol (2011) 1.62
KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation. Nat Clin Pract Cardiovasc Med (2007) 1.56
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. Cerebrovasc Dis (2013) 1.47
Understanding hippocampal sclerosis in the elderly: epidemiology, characterization, and diagnostic issues. Curr Neurol Neurosci Rep (2008) 1.47
TDP-43 is a key player in the clinical features associated with Alzheimer's disease. Acta Neuropathol (2014) 1.47
The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function. Hum Mol Genet (2012) 1.43
Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease. Acta Neuropathol (2013) 1.41
APOE ε4 increases risk for dementia in pure synucleinopathies. JAMA Neurol (2013) 1.41
Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis. Acta Neuropathol (2010) 1.38
TDP-43 pathology, cognitive decline, and dementia in old age. JAMA Neurol (2013) 1.37
Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration. J Biol Chem (2012) 1.37
Hippocampal sclerosis in the elderly: genetic and pathologic findings, some mimicking Alzheimer disease clinically. Alzheimer Dis Assoc Disord (2011) 1.35
TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype. Acta Neuropathol (2011) 1.32
Common variant in GRN is a genetic risk factor for hippocampal sclerosis in the elderly. Neurodegener Dis (2010) 1.31
A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila. Mol Psychiatry (2011) 1.30
Neocortical and hippocampal amyloid-β and tau measures associate with dementia in the oldest-old. Brain (2011) 1.29
KATP channels and cardiovascular disease: suddenly a syndrome. Circ Res (2013) 1.23
Prevalence, laterality, and comorbidity of hippocampal sclerosis in an autopsy sample. Brain Behav (2012) 1.20
TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease. Neurology (2012) 1.18
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. PLoS Genet (2014) 1.17
Hippocampal sclerosis dementia differs from hippocampal sclerosis in frontal lobe degeneration. Acta Neuropathol (2006) 1.16
Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers. Mol Pharmacol (2008) 1.13
Differential clinicopathologic and genetic features of late-onset amnestic dementias. Acta Neuropathol (2014) 1.13
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. Brain (2013) 1.13
Cantú syndrome: report of nine new cases and expansion of the clinical phenotype. Am J Med Genet A (2011) 1.11
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathol (2014) 1.07
Replication of Genome-Wide Association Studies (GWAS) loci for sleep in the British G1219 cohort. Am J Med Genet B Neuropsychiatr Genet (2013) 1.06
The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes. EMBO J (2013) 1.06
TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system. Acta Neuropathol (2007) 1.02
Hippocampal sclerosis of aging is a key Alzheimer's disease mimic: clinical-pathologic correlations and comparisons with both alzheimer's disease and non-tauopathic frontotemporal lobar degeneration. J Alzheimers Dis (2014) 1.00
Endosomal KATP channels as a reservoir after myocardial ischemia: a role for SUR2 subunits. Am J Physiol Heart Circ Physiol (2010) 0.98
Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B. Mol Cell Neurosci (2014) 0.93
Lack of association of the apoE4 allele with hippocampal sclerosis dementia. Neurosci Lett (1996) 0.90
rs5848 variant of progranulin gene is a risk of Alzheimer's disease in the Taiwanese population. Neurodegener Dis (2011) 0.89
TMEM106B a novel risk factor for frontotemporal lobar degeneration. J Mol Neurosci (2011) 0.89
Evolution of ABC transporters by gene duplication and their role in human disease. Biol Chem (2011) 0.85
TMEM106B is a susceptibility locus for Ftld. Nat Rev Neurol (2010) 0.84
TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in Han Chinese. J Neural Transm (Vienna) (2013) 0.83
Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits. Acta Neuropathol Commun (2014) 0.80
TMEM106B expression is reduced in Alzheimer's disease brains. Alzheimers Res Ther (2014) 0.77
Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature (2012) 13.71
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement (2009) 10.21
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature (2009) 8.09
The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers. Alzheimer Dis Assoc Disord (2006) 8.04
Survival after initial diagnosis of Alzheimer disease. Ann Intern Med (2004) 5.52
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychologic test battery. Alzheimer Dis Assoc Disord (2009) 5.50
Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30
The National Alzheimer's Coordinating Center (NACC) database: the Uniform Data Set. Alzheimer Dis Assoc Disord (2007) 5.01
Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial. JAMA (2003) 4.54
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. J Neuropathol Exp Neurol (2012) 3.77
Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol (2014) 3.75
Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010. J Neuropathol Exp Neurol (2012) 3.46
National estimates of the prevalence of Alzheimer's disease in the United States. Alzheimers Dement (2011) 3.42
The National Alzheimer's Coordinating Center (NACC) Database: an Alzheimer disease database. Alzheimer Dis Assoc Disord (2004) 2.97
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nat Genet (2011) 2.97
The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila. Nature (2012) 2.94
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
Subjective memory deterioration and future dementia in people aged 65 and older. J Am Geriatr Soc (2004) 2.74
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58
Depression as a risk factor for Alzheimer disease: the MIRAGE Study. Arch Neurol (2003) 2.56
Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways. Mol Genet Metab (2007) 2.52
Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders. Neuron (2013) 2.45
MicroRNAs (miRNAs) in neurodegenerative diseases. Brain Pathol (2008) 2.39
Age-varying association between statin use and incident Alzheimer's disease. J Am Geriatr Soc (2010) 2.34
The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases. J Mol Biol (2010) 2.20
Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. Physiol Genomics (2008) 2.11
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
Sclerostin and Dickkopf-1 in renal osteodystrophy. Clin J Am Soc Nephrol (2010) 2.06
Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae. Nucleic Acids Res (2007) 1.98
Reversion from mild cognitive impairment to normal or near-normal cognition: risk factors and prognosis. Neurology (2012) 1.90
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics (2006) 1.88
The cobweb of life revealed by genome-scale estimates of horizontal gene transfer. PLoS Biol (2005) 1.79
Thinking outside the box: Alzheimer-type neuropathology that does not map directly onto current consensus recommendations. J Neuropathol Exp Neurol (2010) 1.69
Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study. Arch Neurol (2002) 1.65
Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre. Brain (2013) 1.64
Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. PLoS Genet (2010) 1.56
miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease. Am J Pathol (2010) 1.54
Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center. J Neuropathol Exp Neurol (2013) 1.52
Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient. Brain Pathol (2008) 1.52
Global analysis of RNA secondary structure in two metazoans. Cell Rep (2012) 1.50
Sleep behaviors and sleep quality in children with autism spectrum disorders. Sleep (2009) 1.49
Mutations in Rab3a alter circadian period and homeostatic response to sleep loss in the mouse. Nat Genet (2002) 1.48
Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet (2012) 1.46
Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes. RNA (2009) 1.45
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential. Nucleic Acids Res (2009) 1.44
Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms. Arch Neurol (2012) 1.42
Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease. Acta Neuropathol (2013) 1.41
Statistically based postprocessing of phylogenetic analysis by clustering. Bioinformatics (2002) 1.41
Technical variables in high-throughput miRNA expression profiling: much work remains to be done. Biochim Biophys Acta (2008) 1.36
FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals. PLoS One (2010) 1.34
Associations between microinfarcts and other macroscopic vascular findings on neuropathologic examination in 2 databases. Alzheimer Dis Assoc Disord (2009) 1.34
Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study. BMC Neurol (2010) 1.32
Footwear style and risk of falls in older adults. J Am Geriatr Soc (2004) 1.29
Nonsteroidal anti-inflammatory drugs and risk of Parkinson's disease. Mov Disord (2006) 1.27
MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study. J Alzheimers Dis (2010) 1.26
Differential and dynamic regulation of miR398 in response to ABA and salt stress in Populus tremula and Arabidopsis thaliana. Plant Mol Biol (2009) 1.24
Investigating parent of origin effects in studies of type 2 diabetes and obesity. Curr Diabetes Rev (2008) 1.24
HAMR: high-throughput annotation of modified ribonucleotides. RNA (2013) 1.24
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One (2013) 1.23
CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing. J Neurosci (2013) 1.21
Focus on RNA isolation: obtaining RNA for microRNA (miRNA) expression profiling analyses of neural tissue. Biochim Biophys Acta (2008) 1.19
Genetics of clusterin isoform expression and Alzheimer's disease risk. PLoS One (2012) 1.18
A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls. J Alzheimers Dis (2013) 1.18
Age-varying association between blood pressure and risk of dementia in those aged 65 and older: a community-based prospective cohort study. J Am Geriatr Soc (2007) 1.16
Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. Neurobiol Aging (2010) 1.16
Design of comprehensive Alzheimer's disease centers to address unmet national needs. Alzheimers Dement (2010) 1.14
Genomic landscape of a three-generation pedigree segregating affective disorder. PLoS One (2009) 1.13
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. Brain (2013) 1.13
Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Ann Neurol (2014) 1.12
Correcting population stratification in genetic association studies using a phylogenetic approach. Bioinformatics (2010) 1.08
Specific sequence determinants of miR-15/107 microRNA gene group targets. Nucleic Acids Res (2011) 1.08
Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples. J Biol Chem (2013) 1.07
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathol (2014) 1.07