Published in Cell Death Dis on December 04, 2014
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment. Cell Death Differ (2017) 0.86
The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection. Cell Death Differ (2017) 0.85
Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival. Cell Death Differ (2015) 0.80
The anti-apoptotic Bcl-2 family protein A1/Bfl-1 regulates neutrophil survival and homeostasis and is controlled via PI3K and JAK/STAT signaling. Cell Death Dis (2016) 0.78
MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis. Oncogene (2016) 0.75
Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo. Cell Death Differ (2017) 0.75
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation. Nat Commun (2017) 0.75
Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev (1999) 2.82
Structural plasticity underpins promiscuous binding of the prosurvival protein A1. Structure (2008) 1.42
Multiple gene duplication and expression of mouse bcl-2-related genes, A1. Int Immunol (1998) 1.31
Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice. Blood (2012) 1.25
The stability and anti-apoptotic function of A1 are controlled by its C terminus. J Biol Chem (2006) 1.16
A1/Bfl-1 expression is restricted to TCR engagement in T lymphocytes. Cell Death Differ (2003) 1.03
Mitochondria-dependent caspase-9 activation is necessary for antigen receptor-mediated effector caspase activation and apoptosis in WEHI 231 lymphoma cells. J Immunol (2002) 0.95
NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells. Blood (2008) 0.94
PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors. Cell Death Differ (2014) 0.83
Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice. Cell Death Dis (2014) 0.78
Evidence against upstream regulation of the unfolded protein response (UPR) by pro-apoptotic BIM and PUMA. Cell Death Dis (2014) 0.78