Published in Oncogene on December 08, 2014
Endothelin A receptor drives invadopodia function and cell motility through the β-arrestin/PDZ-RhoGEF pathway in ovarian carcinoma. Oncogene (2015) 0.81
MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma. Arch Pathol Lab Med (2015) 0.79
Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation. Oncotarget (2016) 0.77
Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo. Oncotarget (2016) 0.76
Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase. Sci Rep (2016) 0.75
Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2. Biomaterials (2016) 0.75
E11/Podoplanin Protein Stabilization Through Inhibition of the Proteasome Promotes Osteocyte Differentiation in Murine in Vitro Models. J Cell Physiol (2015) 0.75
Podoplanin, ezrin, and Rho-A proteins may have joint participation in tumor invasion of lip cancer. Clin Oral Investig (2016) 0.75
Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation. J Cell Physiol (2017) 0.75
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin. J Cell Biol (2005) 4.75
The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function. Nat Rev Mol Cell Biol (2011) 4.24
Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function. Cancer Res (2006) 3.83
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J (2003) 3.82
Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell (2006) 3.28
Assembly and biological role of podosomes and invadopodia. Curr Opin Cell Biol (2008) 3.26
ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat Cell Biol (2002) 3.16
Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy. J Clin Oncol (2008) 3.16
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation. J Cell Biol (2009) 2.90
Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition. J Cell Sci (2006) 2.51
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol (2008) 2.39
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia. Curr Biol (2011) 2.34
Degrading devices: invadosomes in proteolytic cell invasion. Annu Rev Cell Dev Biol (2011) 2.33
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites. Clin Cancer Res (2011) 2.31
The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion. Curr Biol (2010) 2.23
The potential role of podoplanin in tumour invasion. Br J Cancer (2006) 2.20
Overexpression of podoplanin in oral cancer and its association with poor clinical outcome. Cancer (2006) 2.04
The cofilin activity cycle in lamellipodia and invadopodia. J Cell Biochem (2009) 1.99
Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas. Int J Cancer (2005) 1.96
Functions of cofilin in cell locomotion and invasion. Nat Rev Mol Cell Biol (2013) 1.95
T1alpha, a lung type I cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth. Dev Biol (2003) 1.89
LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol (2010) 1.79
Invadosomes at a glance. J Cell Sci (2009) 1.70
Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes. J Cell Sci (1999) 1.54
A new role for cortactin in invadopodia: regulation of protease secretion. Eur J Cell Biol (2008) 1.52
Podoplanin: emerging functions in development, the immune system, and cancer. Front Immunol (2012) 1.45
Hic-5 promotes invadopodia formation and invasion during TGF-β-induced epithelial-mesenchymal transition. J Cell Biol (2012) 1.45
Cardiac malformations and myocardial abnormalities in podoplanin knockout mouse embryos: Correlation with abnormal epicardial development. Dev Dyn (2008) 1.43
Lipid rafts and caveolin-1 are required for invadopodia formation and extracellular matrix degradation by human breast cancer cells. Cancer Res (2009) 1.42
Induction of PA2.26, a cell-surface antigen expressed by active fibroblasts, in mouse epidermal keratinocytes during carcinogenesis. Mol Carcinog (1997) 1.38
Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway. J Cell Biol (2011) 1.38
β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell (2013) 1.29
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia. J Cell Biol (2013) 1.28
Adhesion rings surround invadopodia and promote maturation. Biol Open (2012) 1.23
Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis. Cell Rep (2014) 1.22
Podoplanin associates with CD44 to promote directional cell migration. Mol Biol Cell (2010) 1.20
Signaling inputs to invadopodia and podosomes. J Cell Sci (2013) 1.18
Invading one step at a time: the role of invadopodia in tumor metastasis. Oncogene (2013) 1.13
Traversing the basement membrane in vivo: a diversity of strategies. J Cell Biol (2014) 1.11
The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo. J Cell Biol (2013) 1.11
Regulation of cancer invasiveness by the physical extracellular matrix environment. Cell Adh Migr (2009) 1.09
Podoplanin expression in wound and hyperproliferative psoriatic epidermis: regulation by TGF-β and STAT-3 activating cytokines, IFN-γ, IL-6, and IL-22. J Dermatol Sci (2011) 1.05
Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis. J Cell Biol (2014) 1.01
Membrane lipids in invadopodia and podosomes: key structures for cancer invasion and metastasis. Oncotarget (2010) 1.00
Invadopodia biogenesis is regulated by caveolin-mediated modulation of membrane cholesterol levels. J Cell Mol Med (2008) 1.00
Digging a little deeper: the stages of invadopodium formation and maturation. Eur J Cell Biol (2014) 1.00
Induction of podoplanin by transforming growth factor-beta in human fibrosarcoma. FEBS Lett (2007) 0.99
Podoplanin expression during dysplasia-carcinoma sequence in the oral cavity. Tumour Biol (2011) 0.94
The transmembrane domain of podoplanin is required for its association with lipid rafts and the induction of epithelial-mesenchymal transition. Int J Biochem Cell Biol (2011) 0.93
ADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo. J Cell Biol (2014) 0.90
Functional invadopodia formation through stabilization of the PDPN transcript by IMP-3 and cancer-stromal crosstalk for PDPN expression. Carcinogenesis (2012) 0.85
Podoplanin-mediated cell adhesion through extracellular matrix in oral squamous cell carcinoma. Lab Invest (2013) 0.84
D2-40 immunohistochemical overexpression in cutaneous squamous cell carcinomas: a marker of metastatic risk. J Am Acad Dermatol (2012) 0.84
Podoplanin is a substrate of presenilin-1/γ-secretase. Int J Biochem Cell Biol (2013) 0.83
ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasion. PLoS One (2013) 0.83