Current and recent clinical trials for perioperative systemic therapy for muscle invasive bladder cancer: a systematic review.

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Published in BMC Cancer on December 16, 2014

Authors

Vishal Vashistha, David I Quinn, Tanya B Dorff, Siamak Daneshmand1

Author Affiliations

1: Department of Urology, USC/Norris Comprehensive Cancer Center, USC Institute of Urology, 1441 Eastlake Abe, Suite 7416, Los Angeles, CA 90089, USA. daneshma@med.usc.edu.

Associated clinical trials:

DN24-02 as Adjuvant Therapy in Subjects With High Risk HER2+ Urothelial Carcinoma | NCT01353222

Neoadjuvant Dasatinib and Radical Cystectomy for Transitional Cell Carcinoma of the Bladder | NCT00706641

First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma | NCT01215136

Cisplatin, Gemcitabine Hydrochloride, and Sorafenib Tosylate in Treating Patients With Transitional Cell Cancer of the Bladder | NCT01222676

Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer (NRR) | NCT00380029

Gemcitabine, Cisplatin, and Sunitinib (GC-S) as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer | NCT00847015

Comparison of Immediate and Delayed Adjuvant Chemotherapy in Treating Patients Who Have Undergone a Radical Cystectomy for Stage III or Stage IV Transitional Cell Carcinoma of the Bladder Urothelium | NCT00028756

Perioperative Chemotherapy for Patients With Locally Advanced Bladder Cancer (VESPER) | NCT01812369

A Study of the CDX-1307 Vaccine Regimen in Patients With Newly Diagnosed Muscle-Invasive Bladder Cancer (The "N-ABLE" Study) | NCT01094496

Neoadjuvant Erlotinib (Tarceva) in Transitional Cell Carcinoma | NCT00749892

Cisplatin, Bevacizumab, and Gemcitabine Followed by Surgery, Bevacizumab, and Paclitaxel in Treating Patients With Locally Advanced Nonmetastatic Bladder Cancer That Can Be Removed By Surgery | NCT00268450

Trial of Adjuvant Sutent for Patients With High Risk Urothelial Carcinoma After Neoadjuvant Chemotherapy and Cystectomy | NCT01042795

Neoadjuvant Cisplatin, Gemcitabine, Sunitinib Malate + Radical Cystectomy for TCC | NCT00859339

Sunitinib in Treating Patients With Locally Advanced Bladder Cancer | NCT00526656

Safety Study on AdCD40L Gene Therapy for Bladder Cancer | NCT00891748

Neoadjuvant Chemotherapy With Methotrexate, Vinblastine, Adriamycin and Cisplatin (M-VAC) Plus Avastin in Patients With Urothelial Cancer | NCT00506155

Vaccine Therapy in Treating Patients With Transitional Cell Cancer of the Bladder | NCT00070070

Neoadjuvant Rapamycin in Patients Undergoing Radical Cystectomy | NCT01827618

Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer | NCT01938573

Cisplatin and Gemcitabine Compared With Observation in Treating Patients Who Have Undergone Surgery for Bladder Cancer | NCT00054626

Adjuvant Post-radical Cystectomy Treatment for Bladder Cancer | NCT01734798

Combination Chemotherapy in Treating Patients With Bladder Cancer | NCT00003701

Adjuvant Versus Progression-Triggered Gemcitabine Monotherapy for Locally Advanced Bladder Cancer | NCT00146276

Adjuvant Intraarterial Chemotherapy Following Surgery to Treat Locally Advanced Bladder Cancer | NCT01627197

Short-Term Low-Dose Interferon Alfa in Treating Patients With Cancer of the Urothelium | NCT00082719

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