Published in Biophys J on December 16, 2014
Applicability of a computational design approach for synthetic riboswitches. Nucleic Acids Res (2017) 0.75
High-resolution molecular discrimination by RNA. Science (1994) 5.33
The Hill equation revisited: uses and misuses. FASEB J (1997) 3.96
Riboswitches: emerging themes in RNA structure and function. Annu Rev Biophys (2008) 3.75
Ions and RNA folding. Annu Rev Biophys Biomol Struct (2005) 3.37
A decade of riboswitches. Cell (2013) 3.26
Metal ions and RNA folding: a highly charged topic with a dynamic future. Curr Opin Chem Biol (2005) 3.00
A fluorescent indicator for measuring cytosolic free magnesium. Am J Physiol (1989) 2.93
Prospects for riboswitch discovery and analysis. Mol Cell (2011) 2.84
Analysis of thermal melting curves. Oligonucleotides (2003) 2.84
Magnesium. An update on physiological, clinical and analytical aspects. Clin Chim Acta (2000) 2.45
The Hill equation: a review of its capabilities in pharmacological modelling. Fundam Clin Pharmacol (2008) 2.44
Metal ions in the structure and function of RNA. J Biol Inorg Chem (2002) 2.28
The linkage between magnesium binding and RNA folding. J Mol Biol (2002) 2.15
Intermediates and kinetic traps in the folding of a large ribozyme revealed by circular dichroism and UV absorbance spectroscopies and catalytic activity. Nat Struct Biol (1997) 1.93
RNA folding: thermodynamic and molecular descriptions of the roles of ions. Biophys J (2008) 1.90
A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo. Nucleic Acids Res (2004) 1.66
Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis. RNA (2010) 1.58
Conditional gene expression by controlling translation with tetracycline-binding aptamers. Nucleic Acids Res (2003) 1.57
RNA folding: models and perspectives. Curr Opin Struct Biol (2003) 1.56
Tertiary structure of an RNA pseudoknot is stabilized by "diffuse" Mg2+ ions. Biochemistry (2007) 1.53
A thermodynamic framework for the magnesium-dependent folding of RNA. Biopolymers (2003) 1.53
A tetracycline-binding RNA aptamer. Bioorg Med Chem (2001) 1.52
Compact intermediates in RNA folding. Annu Rev Biophys (2010) 1.49
Tetracycline-aptamer-mediated translational regulation in yeast. Mol Microbiol (2003) 1.46
Roles of Mg2+ in TPP-dependent riboswitch. FEBS Lett (2005) 1.46
The dynamic nature of RNA as key to understanding riboswitch mechanisms. Acc Chem Res (2011) 1.39
The ligand-free state of the TPP riboswitch: a partially folded RNA structure. J Mol Biol (2009) 1.39
Screening for engineered neomycin riboswitches that control translation initiation. RNA (2007) 1.38
Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch. Chem Biol (2008) 1.35
Thermodynamic characterization of an engineered tetracycline-binding riboswitch. Nucleic Acids Res (2006) 1.35
Molecular interactions and metal binding in the theophylline-binding core of an RNA aptamer. RNA (2000) 1.32
Concentration, compartmentation and metabolic function of intracellular free Mg2+. Magnes Res (2006) 1.29
A fast and efficient translational control system for conditional expression of yeast genes. Nucleic Acids Res (2009) 1.26
Application of circular dichroism to study RNA folding transitions. Methods Enzymol (2000) 1.25
Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast. Nucleic Acids Res (2007) 1.24
Three-state mechanism couples ligand and temperature sensing in riboswitches. Nature (2013) 1.21
Molecular analysis of a synthetic tetracycline-binding riboswitch. RNA (2005) 1.20
Heat capacity changes associated with nucleic acid folding. Biopolymers (2006) 1.19
An artificial riboswitch for controlling pre-mRNA splicing. RNA (2005) 1.17
Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution. Proc Natl Acad Sci U S A (2013) 1.08
Engineered riboswitches: Expanding researchers' toolbox with synthetic RNA regulators. FEBS Lett (2012) 1.08
De novo design of a synthetic riboswitch that regulates transcription termination. Nucleic Acids Res (2012) 1.07
Themes and variations in riboswitch structure and function. Biochim Biophys Acta (2014) 1.07
Dissecting the influence of Mg2+ on 3D architecture and ligand-binding of the guanine-sensing riboswitch aptamer domain. Nucleic Acids Res (2010) 1.05
Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch. Angew Chem Int Ed Engl (2010) 1.05
Salt-dependent heat capacity changes for RNA duplex formation. J Am Chem Soc (2004) 1.03
Selecting RNA aptamers for synthetic biology: investigating magnesium dependence and predicting binding affinity. Nucleic Acids Res (2010) 0.99
Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection. Nucleic Acids Res (2011) 0.99
Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure. Nucleic Acids Res (2013) 0.98
Artificial riboswitches for gene expression and replication control of DNA and RNA viruses. Proc Natl Acad Sci U S A (2014) 0.96
Heat capacity changes in RNA folding: application of perturbation theory to hammerhead ribozyme cold denaturation. Nucleic Acids Res (2004) 0.96
Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR. RNA (2010) 0.94
The expression platform and the aptamer: cooperativity between Mg2+ and ligand in the SAM-I riboswitch. Nucleic Acids Res (2012) 0.94
Synthetic riboswitches for the conditional control of gene expression in Streptomyces coelicolor. Microbiology (2013) 0.92
Thermodynamics and kinetics of adaptive binding in the malachite green RNA aptamer. Biochemistry (2013) 0.90
Ca2+ and Mg2+ bind tetracycline with distinct stoichiometries and linked deprotonation. Biophys Chem (2007) 0.85
Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity. Nucleic Acids Res (2010) 0.83
Conformational dynamics of the tetracycline-binding aptamer. Nucleic Acids Res (2011) 0.82
Equilibrium and kinetic studies on the interaction of tetracyclines with calcium and magnesium. Biophys Chem (1979) 0.81
Mg(2+)-induced conformational changes in the btuB riboswitch from E. coli. RNA (2013) 0.80
Thermodynamics of ligand binding to a heterogeneous RNA population in the malachite green aptamer. Biochemistry (2011) 0.79
Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain. Nucleic Acids Res (2011) 0.79
Thermodynamic studies of a series of homologous HIV-1 TAR RNA ligands reveal that loose binders are stronger Tat competitors than tight ones. Nucleic Acids Res (2013) 0.78