Published in J Med Chem on October 01, 1989
Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor. ACS Med Chem Lett (2010) 1.14
Design and synthesis of high affinity inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferases directed by ligand efficiency dependent lipophilicity (LELP). J Med Chem (2014) 0.95
3-(2,4-Dichloro-phen-yl)-5-methyl-1,2,4-oxadiazole. Acta Crystallogr Sect E Struct Rep Online (2010) 0.82
3-(2,4-Dichloro-phen-yl)-5-phenyl-1,2,4-oxadiazole. Acta Crystallogr Sect E Struct Rep Online (2010) 0.82
A novel series of non-quaternary oxadiazoles acting as full agonists at muscarinic receptors. Br J Pharmacol (1990) 0.79
An Improved Process for the Synthesis of 4H-Imidazo[1,5-a][1,4]benzodiazepines. Synthesis (Stuttg) (2009) 0.78
Search for α3β₂/₃γ2 subtype selective ligands that are stable on human liver microsomes. Bioorg Med Chem (2012) 0.77
Synthesis and characterization of novel bioactive 1,2,4-oxadiazole natural product analogs bearing the N-phenylmaleimide and N-phenylsuccinimide moieties. Beilstein J Org Chem (2013) 0.75
Benzyl N-{2-[5-(4-chloro-phen-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl}carbamate. Acta Crystallogr Sect E Struct Rep Online (2011) 0.75
(S)-tert-Butyl 3-(3-phenyl-1,2,4-oxa-diazol-5-yl)piperidine-1-carboxyl-ate. Acta Crystallogr Sect E Struct Rep Online (2010) 0.75
5-(2,4-Dichloro-phen-yl)-3-(4-nitro-phen-yl)-1,2,4-oxadiazole. Acta Crystallogr Sect E Struct Rep Online (2010) 0.75
The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry (1998) 65.11
Effectiveness of brief alcohol interventions in primary care populations. Cochrane Database Syst Rev (2007) 10.34
Complex gene conversion events in germline mutation at human minisatellites. Nat Genet (1994) 5.70
Minisatellite repeat coding as a digital approach to DNA typing. Nature (1991) 5.25
Continuity of care and trust in one's physician: evidence from primary care in the United States and the United Kingdom. Fam Med (2001) 4.54
Comparison of standards in training and non-training practices. J R Coll Gen Pract (1985) 4.44
Qualitative methods in research on healthcare quality. Qual Saf Health Care (2002) 4.42
What do we know about how to do audit and feedback? Pitfalls in applying evidence from a systematic review. BMC Health Serv Res (2005) 3.51
Who's for CPR? J R Coll Physicians Lond (1992) 3.28
Impact of the population at risk of diabetes on projections of diabetes burden in the United States: an epidemic on the way. Diabetologia (2006) 3.28
Changing the clinical behavior of doctors: a psychological framework. Qual Health Care (1996) 3.22
Electrotonic coupling between neurons in cat inferior olive. J Neurophysiol (1974) 3.20
A Canadian multicenter study with Zaditen (ketotifen) in the treatment of bronchial asthma in children aged 5 to 17 years. J Allergy Clin Immunol (1989) 3.08
Model for directly assessing and improving clinical competence and performance in revalidation of clinicians. BMJ (2001) 3.05
Features of primary care associated with variations in process and outcome of care of people with diabetes. Br J Gen Pract (2001) 2.95
Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science (1998) 2.83
Changes in sexual behaviour and fear of AIDS. Lancet (1984) 2.76
Clozapine for the treatment of adolescents with schizophrenia. J Am Acad Child Adolesc Psychiatry (1992) 2.68
Promoter trapping identifies real genes in C. elegans. Mol Gen Genet (1998) 2.65
WHO Study on the reliability and validity of the alcohol and drug use disorder instruments: overview of methods and results. Drug Alcohol Depend (1997) 2.59
Guidelines for the ethical conduct of medical research involving children. Royal College of Paediatrics, Child Health: Ethics Advisory Committee. Arch Dis Child (2000) 2.57
Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes. Cochrane Database Syst Rev (2005) 2.46
Can consultants resuscitate? J R Coll Physicians Lond (1992) 2.43
Differentiating between audit and research: postal survey of health authorities' views. BMJ (1999) 2.41
Quality improvement research: understanding the science of change in health care. Qual Saf Health Care (2002) 2.41
Differentiation of atypical atrioventricular node re-entrant tachycardia from orthodromic reciprocating tachycardia using a septal accessory pathway by the response to ventricular pacing. J Am Coll Cardiol (2001) 2.40
Left in limbo: patients' views on care across the primary/secondary interface. Qual Health Care (1999) 2.38
Recent improvements in prediction of protein structure by global optimization of a potential energy function. Proc Natl Acad Sci U S A (2001) 2.31
Jumonji, a nuclear protein that is necessary for normal heart development. Circ Res (2000) 2.26
Randomized controlled trial of brief cognitive behaviour therapy versus treatment as usual in recurrent deliberate self-harm: the POPMACT study. Psychol Med (2003) 2.16
A split binding site for transcription factor tau on the tRNA3Glu gene. EMBO J (1985) 2.16
In vivo intracellular recording and perturbation of persistent activity in a neural integrator. Nat Neurosci (2001) 2.13
Quantifying the contribution of vision to speech perception in noise. Br J Audiol (1987) 2.10
Effectiveness of screening and monitoring tests for diabetic retinopathy--a systematic review. Diabet Med (2000) 2.10
Metastatic malignant mesothelioma presenting as colonic polyps. Hum Pathol (1997) 2.09
Effects of treatment with formoterol on bronchoprotection against methacholine. Am J Med (1998) 1.94
Use of Medicare claims data to evaluate outcomes in elderly patients undergoing lung resection for lung cancer. Chest (1991) 1.91
Cervical cytology consent rate. Lancet (1969) 1.88
Mutation of the gene encoding cellular retinaldehyde-binding protein in autosomal recessive retinitis pigmentosa. Nat Genet (1997) 1.84
Features of primary health care teams associated with successful quality improvement of diabetes care: a qualitative study. Fam Pract (2001) 1.84
The information-seeking behaviour of paediatricians accessing web-based resources. Arch Dis Child (2009) 1.76
Quality assurance in general practice: the state of the art in Europe. Fam Pract (1994) 1.75
Best place of care for older people after acute and during subacute illness: a systematic review. J Health Serv Res Policy (2000) 1.75
The costs and benefits of asking patients for their opinions about general practice. Fam Pract (1996) 1.73
Development of guidelines to facilitate improved support of South Asian carers by primary health care teams. Qual Health Care (2001) 1.72
Structural study of inferior olivary nucleus of the cat: morphological correlates of electrotonic coupling. J Neurophysiol (1974) 1.71
Early referral strategies for management of people with markers of renal disease: a systematic review of the evidence of clinical effectiveness, cost-effectiveness and economic analysis. Health Technol Assess (2010) 1.67
Characteristics of general practices associated with emergency admission rates to hospital: a cross-sectional study. Emerg Med J (2011) 1.65
Introducing a quality improvement programme to primary healthcare teams. Qual Health Care (1998) 1.64
Nitrosation and oxidation in the regulation of gene expression. FASEB J (2000) 1.63
Working from upstream to improve health care: the IHI interdisciplinary professional education collaborative. Jt Comm J Qual Improv (1996) 1.61
Evaluation and management of chronic work-related musculoskeletal disorders of the distal upper extremity. Am J Ind Med (2000) 1.60
Is it time to review the idea of compliance with guidelines? Br J Gen Pract (2001) 1.56
Familial intrahepatic cholestasis 1: studies of localization and function. Hepatology (2001) 1.54
Results of colectomy in elderly patients with colon cancer, based on Medicare claims data. Am J Surg (1992) 1.53
Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism. Nat Genet (1994) 1.50
The dephosphorylation of inositol 1,4-bisphosphate to inositol in liver and brain involves two distinct Li+-sensitive enzymes and proceeds via inositol 4-phosphate. Biochem J (1988) 1.49
Recombinant human erythropoietin for chronic renal failure anaemia in pre-dialysis patients. Cochrane Database Syst Rev (2001) 1.48
Surrogate markers and survival in women receiving first-line combination anthracycline chemotherapy for advanced breast cancer. Br J Cancer (2005) 1.48
The use of pre-operative computed tomography in the assessment of the acute abdomen. Ann R Coll Surg Engl (2012) 1.47
Clinical trial: once-daily mesalamine granules for maintenance of remission of ulcerative colitis - a 6-month placebo-controlled trial. Aliment Pharmacol Ther (2010) 1.47
Setting payment rates for capitated systems: a comparison of various alternatives. Inquiry (1990) 1.47
Psychological interventions for multiple sclerosis. Cochrane Database Syst Rev (2006) 1.47
Effective treatment of an elderly patient with Gaucher's disease and Parkinsonism: a case report of 24 months' oral substrate reduction therapy with miglustat. Parkinsonism Relat Disord (2006) 1.46
Hospitalists for the NHS? J R Soc Med (2000) 1.46
Develop diabetic care in general practice. BMJ (1988) 1.46
Near patient testing for glycated haemoglobin in people with Type 2 diabetes mellitus managed in primary care: acceptability and satisfaction. Diabet Med (2007) 1.45
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts. Proc Natl Acad Sci U S A (2010) 1.45
Screening for depression among acutely ill geriatric inpatients with a short Geriatric Depression Scale. Age Ageing (1997) 1.45
Dupuytren's contracture unfolded. BMJ (2006) 1.45
Contact surface and material nonlinearity modeling of human lungs. Phys Med Biol (2007) 1.45
Crisis, ethics, and the American Medical Association 1847 and 1997. JAMA (1997) 1.44
Double bag or Y-set versus standard transfer systems for continuous ambulatory peritoneal dialysis in end-stage renal disease. Cochrane Database Syst Rev (2001) 1.44
3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. J Med Chem (1996) 1.44
Use of a single solution for oral rehydration and maintenance therapy of infants with diarrhea and mild to moderate dehydration. Pediatrics (1995) 1.43
Microvascular free jejunum transfer. Br J Plast Surg (1982) 1.42
Accuracy of Medicare claims data for estimation of cancer incidence and resection rates among elderly Americans. Med Care (1991) 1.41
Intractable seizures in pregnancy. Lancet (1999) 1.40
Estimation of fetal lung volume using enhanced 3-dimensional ultrasound: a new method and first result. Br J Obstet Gynaecol (1996) 1.40
Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections. Parasite Immunol (2011) 1.40
Electrotonic coupling between neurones in the rat mesencephalic nucleus. J Physiol (1971) 1.39
The value of community mental health nurses based in primary care teams: 'switching the light on in a cellar'. J Psychiatr Ment Health Nurs (2001) 1.39
High latent drug administration error rates associated with the introduction of the international colour coding syringe labelling system. Eur J Anaesthesiol (2006) 1.39
Acute medical assessment units: an efficient alternative to in-hospital acute medical care. Ir Med J (2011) 1.39
Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts. J Cell Biol (1995) 1.38
Steroid and gonadotropin levels in women during the peri-menopausal years. Maturitas (1986) 1.38
VLA integrin expression in normal and diseased human kidney: how should we interpret immunohistochemical data? Nephron (1995) 1.38
Collation and comparison of multi-practice audit data: prevalence and treatment of known diabetes mellitus. Br J Gen Pract (1999) 1.36
The circular genetic map of phage S13. Proc Natl Acad Sci U S A (1967) 1.36
Potentially avoidable emergency department attendance: interview study of patients' reasons for attendance. Emerg Med J (2011) 1.35
Systematic review of the effectiveness and cost-effectiveness, and economic evaluation, of home versus hospital or satellite unit haemodialysis for people with end-stage renal failure. Health Technol Assess (2003) 1.35
mtDNA affinities of the peoples of North-Central Mexico. Am J Hum Genet (2000) 1.34
Quality of care of patients with diabetes: collation of data from multi-practice audits of diabetes in primary care. Fam Pract (1999) 1.34
A survey of audit activity in general practice. Br J Gen Pract (1998) 1.34
A laboratory assessment of ciprofloxacin and comparable antimicrobial agents. Eur J Clin Microbiol (1984) 1.34
A systematic review of discharge arrangements for older people. Health Technol Assess (2002) 1.33
Multicomponent alarm pheromones of the weaver ant. Nature (1975) 1.33
Learning from complaints about general practitioners. BMJ (1999) 1.33
Neuronal activity in prepositus nucleus correlated with eye movement in the alert cat. J Neurophysiol (1982) 1.32