Delayed diagnosis of congenital myasthenia due to associated mitochondrial enzyme defect.

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Published in Neuromuscul Disord on December 10, 2014

Authors

Yiran Guo1, Minal J Menezes2, Manoj P Menezes3, Jinlong Liang4, Dong Li1, Lisa G Riley5, Nigel F Clarke3, P Ian Andrews6, Lifeng Tian1, Richard Webster7, Fengxiang Wang1, Xuanzhu Liu4, Yulan Shen4, David R Thorburn8, Brendan J Keating9, Andrew Engel10, Hakon Hakonarson9, John Christodoulou11, Xun Xu12

Author Affiliations

1: The Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
2: Genetic Metabolic Disorders Research Unit, Western Sydney Genetics Program, The Children's Hospital at Westmead, Sydney, NSW, Australia; Discipline of Paediatrics & Child Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
3: Discipline of Paediatrics & Child Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Institute for Neuroscience and Muscle Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
4: BGI-Shenzhen, Shenzhen 518083, China.
5: Genetic Metabolic Disorders Research Unit, Western Sydney Genetics Program, The Children's Hospital at Westmead, Sydney, NSW, Australia.
6: Department of Neurology, Sydney Children's Hospital, Randwick, NSW, Australia.
7: Institute for Neuroscience and Muscle Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
8: Murdoch Childrens Research Institute and Victorian Clinical Genetics Services, Royal Children's Hospital, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia.
9: The Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, United States; Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Department of Human Genetics Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States.
10: Department of Neurology, Mayo Clinic, Rochester, MN, United States.
11: Genetic Metabolic Disorders Research Unit, Western Sydney Genetics Program, The Children's Hospital at Westmead, Sydney, NSW, Australia; Discipline of Paediatrics & Child Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Discipline of Genetic Medicine, Sydney Medical School, University of Sydney, Sydney, NSW, Australia. Electronic address: john.christodoulou@health.nsw.gov.au.
12: BGI-Shenzhen, Shenzhen 518083, China; The Guangdong Enterprise Key Laboratory of Human Disease Genomics, BGI-Shenzhen, Shenzhen, China.

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