Treatment for preventing tuberculosis in children and adolescents: a randomized clinical trial of a 3-month, 12-dose regimen of a combination of rifapentine and isoniazid.

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🔗 View Article (PMID 25580725)

Published in JAMA Pediatr on March 01, 2015

Authors

M Elsa Villarino1, Nigel A Scott2, Stephen E Weis3, Marc Weiner4, Marcus B Conde5, Brenda Jones6, Sharon Nachman7, Ricardo Oliveira8, Ruth N Moro2, Nong Shang1, Stefan V Goldberg1, Timothy R Sterling9, International Maternal Pediatric and Adolescents AIDS Clinical Trials Group, Tuberculosis Trials Consortium

Author Affiliations

1: Division of Tuberculosis Elimination, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.
2: Division of Tuberculosis Elimination, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia2CDC Foundation, Atlanta, Georgia.
3: Department of Medicine, University of North Texas Health Science Center at Ft Worth.
4: Department of Medicine, Audie L. Murphy San Antonio Veterans Administration Medical Center, San Antonio, Texas.
5: Department of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
6: Department of Medicine, University of Southern California, Los Angeles.
7: Department of Pediatrics, State University of New York at Stony Brook.
8: Department of Pediatrics, Pediatric Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
9: Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

Associated clinical trials:

Three Months of Weekly Rifapentine and Isoniazid for M. Tuberculosis Infection (PREVENT TB) | NCT00023452

Evaluation of the Effect of 3HP vs Periodic 3HP vs 6H in HIV-Positive Individuals (WHIP3TB) | NCT02980016

Taima TB: 3HP Study | NCT02689089

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