Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors.

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Published in Oncotarget on March 10, 2015

Authors

Sebastian Schölch1,2,3, Conrad Rauber4,2,3, Alexandra Tietz2,3, Nuh N Rahbari1, Ulrich Bork1, Thomas Schmidt4, Christoph Kahlert1, Uwe Haberkorn5, Mark A Tomai6, Kenneth E Lipson7, Rafael Carretero8, Jürgen Weitz1, Moritz Koch1, Peter E Huber2,3

Author Affiliations

1: Department of Gastrointestinal, Thoracic and Vascular Surgery, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
2: CCU Molecular and Radiation Oncology, German Cancer Research Center, 69120 Heidelberg, Germany.
3: Department of Radiation Oncology, University Hospital Center, 69120 Heidelberg, Germany.
4: Department of General, Gastrointestinal and Transplant Surgery, University Hospital Heidelberg, Ruprecht-Karls-Universität Heidelberg, 69120 Heidelberg, Germany.
5: Division of Nuclear Medicine, Department of Radiology, University Hospital Heidelberg, Ruprecht-Karls-Universität Heidelberg, 69120 Heidelberg, Germany.
6: 3M, Inc., St. Paul, Minnesota 55121, USA.
7: Fibrogen Inc., San Francisco, California 94158, USA.
8: Division of Molecular Immunology, German Cancer Research Center, 69120 Heidelberg, Germany.

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