Published in Glob Cardiol Sci Pract on July 04, 2012
Early results of sarcomeric gene screening from the Egyptian National BA-HCM Program. J Cardiovasc Transl Res (2012) 0.89
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature (1953) 47.27
A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature (2001) 42.18
Finishing the euchromatic sequence of the human genome. Nature (2004) 41.40
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
The structure of DNA. Cold Spring Harb Symp Quant Biol (1953) 15.08
An initial map of insertion and deletion (INDEL) variation in the human genome. Genome Res (2006) 11.60
Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell (1998) 10.95
Mechanisms of change in gene copy number. Nat Rev Genet (2009) 9.01
Interactome networks and human disease. Cell (2011) 7.16
On protein synthesis. Symp Soc Exp Biol (1958) 6.54
Molecular mechanisms of translational control. Nat Rev Mol Cell Biol (2004) 6.39
Structure and function in the nucleus. Science (1998) 6.26
Executive summary: heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2012) 6.24
Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia. Circulation (2002) 5.94
Central dogma of molecular biology. Nature (1970) 5.89
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy. Circulation (2003) 5.85
Molecular configuration in sodium thymonucleate. Nature (1953) 4.81
Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. Cell (1994) 4.47
Circulating microRNAs are new and sensitive biomarkers of myocardial infarction. Eur Heart J (2010) 4.47
Human diallelic insertion/deletion polymorphisms. Am J Hum Genet (2002) 4.44
Gene-expression profiling for rejection surveillance after cardiac transplantation. N Engl J Med (2010) 4.31
Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing. Heart Rhythm (2005) 4.21
Molecular structure of deoxypentose nucleic acids. Nature (1953) 3.92
Genetic evaluation of cardiomyopathy--a Heart Failure Society of America practice guideline. J Card Fail (2009) 3.54
Myosin binding protein C mutations and compound heterozygosity in hypertrophic cardiomyopathy. J Am Coll Cardiol (2004) 3.47
The mRNA poly(A)-binding protein: localization, abundance, and RNA-binding specificity. Exp Cell Res (1994) 3.06
The dynamics of chromosome organization and gene regulation. Annu Rev Biochem (2003) 2.71
Signature microRNA expression profile of essential hypertension and its novel link to human cytomegalovirus infection. Circulation (2011) 2.60
Influence of histone H1 on chromatin structure. Cell (1977) 2.17
Diagnostic, prognostic, and therapeutic implications of genetic testing for hypertrophic cardiomyopathy. J Am Coll Cardiol (2009) 2.14
Shared genetic causes of cardiac hypertrophy in children and adults. N Engl J Med (2008) 2.12
Helical structure of crystalline deoxypentose nucleic acid. Nature (1953) 2.09
Tales of poly(A): a review. Gene (1990) 2.08
Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling. J Med Genet (2005) 2.04
Genetics of human cardiovascular disease. Cell (2012) 1.90
Clinical features and outcome of hypertrophic cardiomyopathy associated with triple sarcomere protein gene mutations. J Am Coll Cardiol (2010) 1.80
Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy. Eur Heart J (2006) 1.78
Mining treasures from 'junk DNA'. Science (1994) 1.65
Genetic counselling and testing in cardiomyopathies: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J (2010) 1.58
Mechanisms of disease: hypertrophic cardiomyopathy. Nat Rev Cardiol (2011) 1.55
Metagenomic detection of phage-encoded platelet-binding factors in the human oral cavity. Proc Natl Acad Sci U S A (2010) 1.53
Site-specific initiation of transcription by RNA polymerase II. Proc Soc Exp Biol Med (1993) 1.43
DNA testing for hypertrophic cardiomyopathy: a cost-effectiveness model. Eur Heart J (2010) 1.40
Distinct epigenomic features in end-stage failing human hearts. Circulation (2011) 1.39
Evidence for 2-chain helix in crystalline structure of sodium deoxyribonucleate. Nature (1953) 1.35
Pre-mRNA secondary structure and the regulation of splicing. Bioessays (1993) 1.29
Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice. Circ Res (2009) 1.26
Multiple mutations in genetic cardiovascular disease: a marker of disease severity? Circ Cardiovasc Genet (2009) 1.18
The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy. Eur Heart J (2008) 1.17
Genomics. DNA study forces rethink of what it means to be a gene. Science (2007) 1.13
Possible gene dose effect of a mutant cardiac beta-myosin heavy chain gene on the clinical expression of familial hypertrophic cardiomyopathy. Biochem Biophys Res Commun (1994) 1.12
Gene profiling changes in cytoskeletal proteins during clinical recovery after left ventricular-assist device support. Circulation (2005) 1.10
Genetic counseling and testing for hypertrophic cardiomyopathy: the pediatric perspective. J Cardiovasc Transl Res (2009) 1.10
Two cases of severe neonatal hypertrophic cardiomyopathy caused by compound heterozygous mutations in the MYBPC3 gene. J Med Genet (2006) 1.10
Genetic counseling and testing for hypertrophic cardiomyopathy: an adult perspective. J Cardiovasc Transl Res (2009) 1.06
Hypertrophic cardiomyopathy: two homozygous cases with "typical" hypertrophic cardiomyopathy and three new mutations in cases with progression to dilated cardiomyopathy. Biochem Biophys Res Commun (2003) 1.06
Nonrandom distribution of repeated DNA sequences with respect to supercoiled loops and the nuclear matrix. Proc Natl Acad Sci U S A (1982) 1.04
Developmental origins of hypertrophic cardiomyopathy phenotypes: a unifying hypothesis. Nat Rev Cardiol (2009) 1.01
A molecular screening strategy based on beta-myosin heavy chain, cardiac myosin binding protein C and troponin T genes in Italian patients with hypertrophic cardiomyopathy. J Cardiovasc Med (Hagerstown) (2006) 1.01
A cap for all occasions. Structure (1997) 0.98
Predicting the total number of human genes. Nat Genet (1994) 0.90
Genetic testing and genetic counseling in cardiovascular genetic medicine: overview and preliminary recommendations. Congest Heart Fail (2008) 0.90
Cardiovascular genetic medicine: evolving concepts, rationale, and implementation. J Cardiovasc Transl Res (2008) 0.87
Role of animal models in HCM research. J Cardiovasc Transl Res (2009) 0.84
Guidelines for the diagnosis and management of hypertrophic cardiomyopathy. Heart Lung Circ (2006) 0.80
Partial characterization of nuclear matrix attachment regions from human fibroblast DNA using Alu-polymerase chain reaction. Cancer Res (1992) 0.76
THE COMPLEMENTARY STRUCTURE OF DNA. Proc Natl Acad Sci U S A (1954) 0.76
Science and practice of arrhythmogenic cardiomyopathy: A paradigm shift. Glob Cardiol Sci Pract (2013) 0.81