Prognostic impact of transcription factor Fra-1 in ER-positive breast cancer: contribution to a metastatic phenotype through modulation of tumor cell adhesive properties.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 25666264)

Published in J Cancer Res Clin Oncol on February 10, 2015

Authors

L Oliveira-Ferrer1, M Kürschner, V Labitzky, D Wicklein, V Müller, G Lüers, U Schumacher, K Milde-Langosch, C Schröder

Author Affiliations

1: Department of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Bldg. N27, 20246, Hamburg, Germany, ferrer@uke.de.

Articles cited by this

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta (1991) 11.78

AP-1 as a regulator of cell life and death. Nat Cell Biol (2002) 10.10

Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature (1988) 5.18

AP-1 subunits: quarrel and harmony among siblings. J Cell Sci (2004) 5.08

The Fos family of transcription factors and their role in tumourigenesis. Eur J Cancer (2005) 2.63

Fos/AP-1 proteins in bone and the immune system. Immunol Rev (2005) 2.58

CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bone marrow endothelial cells. Cancer Res (2004) 2.51

CD44, a therapeutic target for metastasising tumours. Eur J Cancer (2010) 2.50

AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise? Cell Signal (2010) 2.49

Fra-1 induces morphological transformation and increases in vitro invasiveness and motility of epithelioid adenocarcinoma cells. Mol Cell Biol (1998) 2.22

Identification of gene expression profiles that predict the aggressive behavior of breast cancer cells. Cancer Res (2001) 2.01

Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. BMC Med (2012) 1.85

Targeting selectins and selectin ligands in inflammation and cancer. Expert Opin Ther Targets (2007) 1.82

FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells. Oncogene (2005) 1.74

Stepping out of the flow: capillary extravasation in cancer metastasis. Clin Exp Metastasis (2007) 1.68

Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen). Cancer Res (2005) 1.56

Endothelial cell adhesion molecules and cancer progression. Curr Med Chem (2007) 1.55

cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype. Oncogene (1999) 1.42

CD44v4 is a major E-selectin ligand that mediates breast cancer cell transendothelial migration. PLoS One (2008) 1.36

Fra-1 a target for cancer prevention or intervention. Gene (2006) 1.35

Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently. Mol Cell Biol (2002) 1.26

Fos-related antigen 1 modulates malignant features of glioma cells. Mol Cancer Res (2005) 1.20

Mechanisms by which E-selectin regulates diapedesis of colon cancer cells under flow conditions. Cancer Res (2008) 1.19

Accumulation of Fra-1 in ras-transformed cells depends on both transcriptional autoregulation and MEK-dependent posttranslational stabilization. Mol Cell Biol (2003) 1.18

Structure and function of cell adhesion molecules. Am J Med (1999) 1.17

FRA-1 expression level modulates regulation of activator protein-1 activity by estradiol in breast cancer cells. Mol Endocrinol (1998) 1.17

Expression pattern of the AP-1 family in breast cancer: association of fosB expression with a well-differentiated, receptor-positive tumor phenotype. Int J Cancer (1999) 1.16

Extravasation of leukocytes in comparison to tumor cells. Cell Commun Signal (2008) 1.16

miR-221/222 targeting of trichorhinophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer. Sci Signal (2011) 1.16

The role of the AP-1 transcription factors c-Fos, FosB, Fra-1 and Fra-2 in the invasion process of mammary carcinomas. Breast Cancer Res Treat (2004) 1.14

Predictive impact of activated leukocyte cell adhesion molecule (ALCAM/CD166) in breast cancer. Breast Cancer Res Treat (2008) 1.12

Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression. Mol Oncol (2009) 1.10

FRA-1 expression in hyperplastic and neoplastic thyroid diseases. Clin Cancer Res (2000) 1.10

FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders. BMC Cancer (2007) 1.03

Expression pattern of the AP-1 family in endometrial cancer: correlations with cell cycle regulators. J Cancer Res Clin Oncol (2001) 0.99

Genome-wide profiling of AP-1-regulated transcription provides insights into the invasiveness of triple-negative breast cancer. Cancer Res (2014) 0.96

The molecular role of Fra-1 and its prognostic significance in human esophageal squamous cell carcinoma. Cancer (2011) 0.95

c-FOS suppresses ovarian cancer progression by changing adhesion. Br J Cancer (2013) 0.95

An association of a simultaneous nuclear and cytoplasmic localization of Fra-1 with breast malignancy. BMC Cancer (2006) 0.91

Expression of cell-cycle regulatory proteins in endometrial carcinomas: correlations with hormone receptor status and clinicopathologic parameters. J Cancer Res Clin Oncol (2001) 0.89

Role of Fos-related antigen 1 in the progression and prognosis of ductal breast carcinoma. Histopathology (2011) 0.89

Genomic structure and transcriptional regulation of the human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene. J Mol Endocrinol (2003) 0.89

The transcription factor Fra-2 promotes mammary tumour progression by changing the adhesive properties of breast cancer cells. Eur J Cancer (2010) 0.86

Adhesion of small cell lung cancer cells to E- and P-selectin under physiological flow conditions: implications for metastasis formation. Histochem Cell Biol (2011) 0.86

Influence of L1-CAM expression of breast cancer cells on adhesion to endothelial cells. J Cancer Res Clin Oncol (2012) 0.85

Aberrant expression of Fra-1 in estrogen receptor-negative breast cancers and suppression of their propagation in vivo by ascochlorin, an antibiotic that inhibits cellular activator protein-1 activity. J Antibiot (Tokyo) (2007) 0.81

Articles by these authors

Detection and identification of fungal pathogens in blood by using molecular probes. J Clin Microbiol (1997) 5.86

A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene. Cell (1986) 4.39

In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood (2000) 3.57

Quantification of fungal DNA by using fluorescence resonance energy transfer and the light cycler system. J Clin Microbiol (2000) 3.02

Clonal deletion of V beta 14-bearing T cells in mice transgenic for mammary tumour virus. Nature (1991) 2.76

Resistance to fluconazole and cross-resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol delta5,6-desaturation. FEBS Lett (1997) 2.72

X-linked Alport syndrome: natural history in 195 families and genotype- phenotype correlations in males. J Am Soc Nephrol (2000) 2.71

Molecular analysis of cyp51 from fluconazole-resistant Candida albicans strains. FEMS Microbiol Lett (1997) 2.15

Comparison of different methods for extraction of DNA of fungal pathogens from cultures and blood. J Clin Microbiol (1997) 2.13

What do people think about when they answer the Brief Illness Perception Questionnaire? A 'think-aloud' study. Br J Health Psychol (2011) 2.10

Primary B-cell gastric lymphoma: a clinicopathological study of 145 patients. Gastroenterology (1991) 1.94

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model. Am J Pathol (2001) 1.81

Osmoadaptation in bacteria and archaea: common principles and differences. Environ Microbiol (2001) 1.81

Duration and frequency of every day activities in total hip patients. J Biomech (2001) 1.80

Direct and reversible hydrogenation of CO2 to formate by a bacterial carbon dioxide reductase. Science (2013) 1.78

cis-acting control elements for Krüppel expression in the Drosophila embryo. EMBO J (1990) 1.70

Derivation of a new hematopoietic cell line with endothelial features from a patient with transformed myeloproliferative syndrome: a case report. Cancer (2000) 1.60

Exploration of Victoria crater by the Mars rover Opportunity. Science (2009) 1.56

Cisplatin nephrotoxicity aggravated by cardiovascular disease and diabetes in lung cancer patients. Eur Respir J (2010) 1.55

Sodium dependence of acetate formation by the acetogenic bacterium Acetobacterium woodii. J Bacteriol (1989) 1.55

Bioenergetics of the Archaea. Microbiol Mol Biol Rev (1999) 1.52

Posterior segmentation of the Drosophila embryo in the absence of a maternal posterior organizer gene. Nature (1989) 1.51

Resting energy expenditure in obese children aged 4 to 15 years: measured versus predicted data. Acta Paediatr (2004) 1.49

Patellar tracking patterns during active and passive knee extension: evaluation with motion-triggered cine MR imaging. Radiology (1993) 1.48

Early detection of aspergillus infection after allogeneic stem cell transplantation by polymerase chain reaction screening. J Infect Dis (2000) 1.47

Subdivision of flagellar region III of the Escherichia coli and Salmonella typhimurium chromosomes and identification of two additional flagellar genes. J Gen Microbiol (1992) 1.43

[Abdominal organ retrieval: strategies to improve quality]. Chirurg (2013) 1.38

N5-methyl-tetrahydromethanopterin:coenzyme M methyltransferase of Methanosarcina strain Gö1 is an Na(+)-translocating membrane protein. J Bacteriol (1992) 1.36

Presence of a sodium-translocating ATPase in membrane vesicles of the homoacetogenic bacterium Acetobacterium woodii. Eur J Biochem (1992) 1.34

PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel and CMF versus a standard-dosed epirubicin/cyclophosphamide followed by paclitaxel ± darbepoetin alfa in primary breast cancer--results at the time of surgery. Ann Oncol (2011) 1.33

Comparison between plasma and whole blood specimens for detection of Aspergillus DNA by PCR. J Clin Microbiol (2000) 1.33

Chemokine CXCL13 is overexpressed in the tumour tissue and in the peripheral blood of breast cancer patients. Br J Cancer (2008) 1.29

Purification of ATP synthase from Acetobacterium woodii and identification as a Na(+)-translocating F1F0-type enzyme. Eur J Biochem (1994) 1.28

Cardiovascular effects of tricyclic and tetracyclic antidepressants. JAMA (1978) 1.27

The carboxy-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists. Mol Endocrinol (1995) 1.27

Establishing glycaemic control with continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes: experience of the PedPump Study in 17 countries. Diabetologia (2008) 1.27

PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel, and CMF versus a standard-dosed epirubicin-cyclophosphamide followed by paclitaxel with or without darbepoetin alfa in primary breast cancer--outcome on prognosis. Ann Oncol (2011) 1.26

Expression and prognostic relevance of activated extracellular-regulated kinases (ERK1/2) in breast cancer. Br J Cancer (2005) 1.22

Lipopolysaccharide pretreatment protects from renal ischemia/reperfusion injury : possible connection to an interleukin-6-dependent pathway. Am J Pathol (2000) 1.21

Prospective screening by a panfungal polymerase chain reaction assay in patients at risk for fungal infections: implications for the management of febrile neutropenia. Br J Haematol (2000) 1.20

Escherichia coli produces a cytoplasmic alpha-amylase, AmyA. J Bacteriol (1992) 1.18

Gene expression of topoisomerase II alpha (TOP2A) by microarray analysis is highly prognostic in estrogen receptor (ER) positive breast cancer. Breast Cancer Res Treat (2008) 1.17

Expression pattern of the AP-1 family in breast cancer: association of fosB expression with a well-differentiated, receptor-positive tumor phenotype. Int J Cancer (1999) 1.16

Hemodialysis in children: general practical guidelines. Pediatr Nephrol (2005) 1.16

Nephrotoxicity associated with ifosfamide. Eur J Pediatr (1988) 1.14

Predictive impact of activated leukocyte cell adhesion molecule (ALCAM/CD166) in breast cancer. Breast Cancer Res Treat (2008) 1.12

E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung. Br J Cancer (2009) 1.12

Localization of the gene for X-linked Alport's syndrome. Kidney Int (1988) 1.12

Creating a high-resolution spatial/symbolic model of the inner organs based on the Visible Human. Med Image Anal (2001) 1.11

Rat intestinal mucosal responses to a microbial flora and different diets. Gut (1995) 1.10

[Normal flora of the human conjunctiva: examination of 135 persons of various ages]. Klin Monbl Augenheilkd (1994) 1.09

Prevention and treatment of renal osteodystrophy in children on chronic renal failure: European guidelines. Pediatr Nephrol (2005) 1.09

Characterization of the mRNA and cloned cDNA specifying the third component of mouse complement. Proc Natl Acad Sci U S A (1982) 1.09

Human papillomavirus type 13 and focal epithelial hyperplasia of the oral mucosa: DNA hybridization on paraffin-embedded specimens. Virchows Arch A Pathol Anat Histopathol (1987) 1.09

Interaction of microtubules with peroxisomes. Tubular and spherical peroxisomes in HepG2 cells and their alterations induced by microtubule-active drugs. Eur J Cell Biol (1996) 1.08

C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma. Br J Cancer (2008) 1.08

Structure-function relationships of A-, F- and V-ATPases. J Exp Biol (2001) 1.08

Kinetics of electrogenic transport by the ADP/ATP carrier. Biophys J (1999) 1.08

Immunohistological evidences of cortical and medullary differentiation in thymoma. Virchows Arch A Pathol Anat Histopathol (1985) 1.07

Sodium ions and an energized membrane required by Methanosarcina barkeri for the oxidation of methanol to the level of formaldehyde. J Bacteriol (1985) 1.06

Phospholipid and sterol analysis of plasma membranes of azole-resistant Candida albicans strains. FEMS Microbiol Lett (2000) 1.05

Angiotensin II increases the intracellular calcium activity in podocytes of the intact glomerulus. Kidney Int (2000) 1.04

Nucleic acid sequence-based amplification of Aspergillus RNA in blood samples. J Clin Microbiol (2001) 1.03

Helix pomatia agglutinin lectin-binding oligosaccharides of aggressive breast cancer. Int J Cancer (2001) 1.02

Pseudomonas aeruginosa II lectin stops human ciliary beating: therapeutic implications of fucose. Am J Respir Crit Care Med (1997) 1.01

Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer. Oncogene (2010) 1.01

[Undifferentiated, embryonal sarcoma as a rare cause of spontaneous liver rupture in adults]. Chirurg (2000) 1.00

Trastuzumab in pregnancy associated with poor fetal outcome. Ann Oncol (2007) 1.00

Generation of a transmembrane gradient of Na+ in Methanosarcina barkeri. Eur J Biochem (1987) 1.00

Characterization of gP85gag as an antigen recognized by Moloney leukemia virus-specific cytolytic T cell clones that function in vivo. J Exp Med (1985) 1.00

Regulatory and coding regions of the segmentation gene hunchback are functionally conserved between Drosophila virilis and Drosophila melanogaster. Mech Dev (1994) 0.99

Expression pattern of the AP-1 family in endometrial cancer: correlations with cell cycle regulators. J Cancer Res Clin Oncol (2001) 0.99

Probing the role of positive residues in the ADP/ATP carrier from yeast. The effect of six arginine mutations on transport and the four ATP versus ADP exchange modes. Biochemistry (1996) 0.98

Progesterone receptor isoforms, PR-B and PR-A, in breast cancer: correlations with clinicopathologic tumor parameters and expression of AP-1 factors. Horm Res (2000) 0.98

Cine MR imaging before and after realignment surgery for patellar maltracking -- comparison with axial radiographs. Skeletal Radiol (1995) 0.98

Outcome of operative therapy of hepatic metastatic stomach carcinoma: a retrospective analysis. World J Surg (2012) 0.97

Biphasic expression of stromal cell-derived factor-1 during human wound healing. Br J Dermatol (2007) 0.97

Effects of LHRH-analogues on mitogenic signal transduction in cancer cells. J Steroid Biochem Mol Biol (1998) 0.97

The Na(+)-F(1)F(0)-ATPase operon from Acetobacterium woodii. Operon structure and presence of multiple copies of atpE which encode proteolipids of 8- and 18-kda. J Biol Chem (1999) 0.97

PAS-positive loops and networks as a prognostic indicator in cutaneous malignant melanoma. J Pathol (2001) 0.97

A simple and rapid technique to process formalin-fixed, paraffin-embedded tissues for the detection of viruses by the polymerase chain reaction. Virchows Arch A Pathol Anat Histopathol (1992) 0.96

Delta mu Na+ drives the synthesis of ATP via an delta mu Na(+)-translocating F1F0-ATP synthase in membrane vesicles of the archaeon Methanosarcina mazei Gö1. J Bacteriol (1994) 0.96

Successful treatment of Pseudomonas aeruginosa respiratory tract infection with a sugar solution--a case report on a lectin based therapeutic principle. Klin Padiatr (2001) 0.95

Gene amplification in ductal carcinoma in situ of the breast. Breast Cancer Res Treat (2009) 0.95

cis Interaction of the cell adhesion molecule CEACAM1 with integrin beta(3). Am J Pathol (2001) 0.95

Ancient impact and aqueous processes at Endeavour Crater, Mars. Science (2012) 0.95

Differential transformation of C3H10T1/2 cells by v-mos: sequential expression of transformation parameters. Mol Cell Biol (1985) 0.95

Clinically proven markers of metastasis predict metastatic spread of human melanoma cells engrafted in scid mice. Br J Cancer (2007) 0.95

A sodium-stimulated ATP synthase in the acetogenic bacterium Acetobacterium woodii. FEBS Lett (1991) 0.94

Quantitative assessment of spontaneous lung metastases of human HT29 colon cancer cells transplanted into SCID mice. Cancer Lett (2000) 0.94

Human papillomavirus DNA in oral squamous cell carcinomas and normal mucosa. J Oral Pathol Med (1994) 0.94

Identification of subunits a, b, and c1 from Acetobacterium woodii Na+-F1F0-ATPase. Subunits c1, c2, AND c3 constitute a mixed c-oligomer. J Biol Chem (2000) 0.94

Procalcitonin in the setting of complicated postoperative course after liver transplantation. Transplant Proc (2010) 0.93

Rapid detection of point mutations by fluorescence resonance energy transfer and probe melting curves in Candida species. Clin Chem (2000) 0.93

Epithelial glycoprotein-2 expression is subject to regulatory processes in epithelial-mesenchymal transitions during metastases: an investigation of human cancers transplanted into severe combined immunodeficient mice. Histochem J (1998) 0.93

Lectin binding to cutaneous malignant melanoma: HPA is associated with metastasis formation. Br J Cancer (2001) 0.93

Intracellular delivery of trehalose into mammalian cells by electropermeabilization. J Membr Biol (2002) 0.93

Structural Insights into the A1 ATPase from the archaeon, Methanosarcina mazei Gö1. Biochemistry (2001) 0.92