Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9.

PubWeight™: 0.84‹?›

🔗 View Article (PMID 25681461)

Published in FASEB J on February 13, 2015

Authors

Ganna Aleshcheva1, Markus Wehland1, Jayashree Sahana1, Johann Bauer1, Thomas J Corydon1, Ruth Hemmersbach1, Timo Frett1, Marcel Egli1, Manfred Infanger1, Jirka Grosse1, Daniela Grimm2

Author Affiliations

1: *Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany; Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Max-Planck-Institute for Biochemistry, Martinsried, Germany; DLR German Aerospace Center, Biomedical Research, Gravitational Biology, Cologne, Germany; Aerospace Biomedical Science and Technology, Space Biology Group, Luzerne University of Applied Sciences and Arts, Hergiswil, Switzerland; and Department of Nuclear Medicine, University of Regensburg, Regensburg, Germany.
2: *Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany; Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Max-Planck-Institute for Biochemistry, Martinsried, Germany; DLR German Aerospace Center, Biomedical Research, Gravitational Biology, Cologne, Germany; Aerospace Biomedical Science and Technology, Space Biology Group, Luzerne University of Applied Sciences and Arts, Hergiswil, Switzerland; and Department of Nuclear Medicine, University of Regensburg, Regensburg, Germany dgg@biomed.au.dk.