Kinin B1 receptor antagonism is equally efficient as angiotensin receptor 1 antagonism in reducing renal fibrosis in experimental obstructive nephropathy, but is not additive.

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Published in Front Pharmacol on February 02, 2015

Authors

Antoine Huart1, Julie Klein2, Julien Gonzalez2, Bénédicte Buffin-Meyer2, Eric Neau2, Christine Delage2, Denis Calise3, David Ribes1, Joost P Schanstra2, Jean-Loup Bascands2

Author Affiliations

1: Institut National de la Santé et de la Recherche Médicale U1048, Institute of Cardiovascular and Metabolic Disease Toulouse, France ; Department of Nephrology, CHU-Rangueil Toulouse, France.
2: Institut National de la Santé et de la Recherche Médicale U1048, Institute of Cardiovascular and Metabolic Disease Toulouse, France ; Université Toulouse III Paul-Sabatier Toulouse, France.
3: Université Toulouse III Paul-Sabatier Toulouse, France ; Unité mixte de Service US006, CHU-Rangueil Toulouse, France.

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