Reverse genetics of Mononegavirales: How they work, new vaccines, and new cancer therapeutics.

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Published in Virology on February 18, 2015

Authors

Christian K Pfaller1, Roberto Cattaneo2, Matthias J Schnell3

Author Affiliations

1: Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
2: Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: Cattaneo.Roberto@mayo.edu.
3: Department of Microbiology and Immunology, Philadelphia, PA 19107, USA; Jefferson Vaccine Center, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address: Matthias.schnell@jefferson.edu.

Associated clinical trials:

Viral Therapy in Treating Patient With Liver Cancer | NCT01628640

Viral Therapy in Treating Patients With Recurrent Glioblastoma Multiforme | NCT00390299

Vaccine Therapy With or Without Cyclophosphamide in Treating Patients With Recurrent or Refractory Multiple Myeloma | NCT00450814

Recombinant Measles Virus Vaccine Therapy and Oncolytic Virus Therapy in Treating Patients With Progressive, Recurrent, or Refractory Ovarian Epithelial Cancer or Primary Peritoneal Cancer | NCT00408590

Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma | NCT01503177

Evaluating the Safety of and Immune Response to the VSV-Indiana HIV Vaccine in Healthy, HIV-Uninfected Adults | NCT01438606

MV-NIS Infected Mesenchymal Stem Cells in Treating Patients With Recurrent Ovarian Cancer | NCT02068794

Viral Therapy In Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Cancer or Metastatic Breast Cancer | NCT01846091

VSV-ZEBOV Geneva Vaccine Trial (VSV-ZEBOV) | NCT02287480

Partnership for Research on Ebola Vaccines in Liberia (PREVAIL) | NCT02344407

Safety and Immunogenicity of Prime-Boost Vesicular Stomatitis Virus (VSV) Ebola Vaccine in Healthy Adults (V920-002) | NCT02280408

A Study to Find Out if the New Ebola Vaccine is Safe and Stimulates Immunity That Might Protect Adults in Kilifi, Kenya. | NCT02296983

Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine (rVSVΔG-ZEBOV-GP) | NCT02283099

Study to Evaluate the Dosage and Safety of Two Intramuscular Injections of an Investigational Clade B HIV Vaccine | NCT01320176

Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children | NCT01852266

Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in Infants and Children | NCT01893554

Placebo Controlled, Dose Response, Safety and Immunogenicity Study of Vesicular Stomatitis Virus (VSV) Ebola Vaccine in Healthy Adults (V920-004) | NCT02314923

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