A novel target for oral cancer chemoprevention? Notch quite, yet….

A new complementary procedure for patients affected by head and neck cancer: Chemo-predictive assay. Int J Surg Case Rep (2016) 0.76

Targeted sequencing reveals TP53 as a potential diagnostic biomarker in the post-treatment surveillance of head and neck cancer. Oncotarget (2016) 0.75

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science (2004) 18.84

The mutational landscape of head and neck squamous cell carcinoma. Science (2011) 16.88

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science (2011) 11.12

Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res (1996) 4.89

Therapeutic antibody targeting of individual Notch receptors. Nature (2010) 4.56

Oral leukoplakia and malignant transformation. A follow-up study of 257 patients. Cancer (1984) 4.46

Loss of heterozygosity (LOH) profiles--validated risk predictors for progression to oral cancer. Cancer Prev Res (Phila) (2012) 3.03

Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells. Blood (2008) 2.94

Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia. Clin Cancer Res (2000) 2.71

Incidence rates of oral cancer and natural history of oral precancerous lesions in a 10-year follow-up study of Indian villagers. Community Dent Oral Epidemiol (1980) 2.43

Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma. Blood (2011) 2.36

Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment. Nat Med (1996) 2.29

Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer. Cancer Prev Res (Phila) (2010) 1.80

3p14 and 9p21 loss is a simple tool for predicting second oral malignancy at previously treated oral cancer sites. Cancer Res (2002) 1.75

Therapeutic modulation of Notch signalling--are we there yet? Nat Rev Drug Discov (2014) 1.73

Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups. Nat Commun (2013) 1.62

Notch1 mutations are drivers of oral tumorigenesis. Cancer Prev Res (Phila) (2014) 1.58

NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome. Leukemia (2012) 1.41

A transcriptional progression model for head and neck cancer. Clin Cancer Res (2003) 1.06

Common and complex Notch1 mutations in Chinese oral squamous cell carcinoma. Clin Cancer Res (2013) 0.93

Oral premalignant lesions: any progress with systemic therapies? Curr Opin Oncol (2012) 0.87

The challenge of targeting notch in hematologic malignancies. Front Pediatr (2014) 0.78

Mutational landscape of aggressive cutaneous squamous cell carcinoma. Clin Cancer Res (2014) 1.47

Genome-wide association study identifies common genetic variants associated with salivary gland carcinoma and its subtypes. Cancer (2015) 0.82

New DNA Methylation Markers and Global DNA Hypomethylation Are Associated with Oral Cancer Development. Cancer Prev Res (Phila) (2015) 0.78

Comparison of systemic therapies used concurrently with radiation for the treatment of human papillomavirus-associated oropharyngeal cancer. Head Neck (2015) 0.77

Final Report of a Prospective Randomized Trial to Evaluate the Dose-Response Relationship for Postoperative Radiation Therapy and Pathologic Risk Groups in Patients With Head and Neck Cancer. Int J Radiat Oncol Biol Phys (2017) 0.75

Long-term outcomes after multidisciplinary management of T3 laryngeal squamous cell carcinomas: Improved functional outcomes and survival with modern therapeutic approaches. Head Neck (2016) 0.75