Published in Nat Cell Biol on March 01, 2015
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors. Genes Dev (1998) 2.66
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2. Cell (2013) 2.16
Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase. Nature (2006) 2.15
A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell (2011) 1.86
Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac. Cancer Res (2007) 1.71
The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation. Genes Dev (1997) 1.67
The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell (2010) 1.67
Collective cell migration: a mechanistic perspective. Physiology (Bethesda) (2013) 1.58
A molecular mechanotransduction pathway regulates collective migration of epithelial cells. Nat Cell Biol (2015) 1.52
The Nf2 tumor suppressor regulates cell-cell adhesion during tissue fusion. Proc Natl Acad Sci U S A (2007) 1.17
Molecular insights into NF2/Merlin tumor suppressor function. FEBS Lett (2014) 1.03
Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K. Sci Rep (2015) 1.03