Helicobacter pylori: Genomic Insight into the Host-Pathogen Interaction.

PubWeight™: 0.77‹?›

🔗 View Article (PMC 4334614)

Published in Int J Genomics on February 05, 2015

Authors

Kathryn P Haley1, Jennifer A Gaddy2

Author Affiliations

1: Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
2: Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA ; Tennessee Valley Healthcare Systems, US Department of Veterans Affairs, F523-ACRE Building, 1310 24th Avenue South, Nashville, TN 37212, USA.

Articles cited by this

Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production. Infect Immun (1993) 7.75

The primary transcriptome of the major human pathogen Helicobacter pylori. Nature (2010) 7.70

Purification and characterization of the vacuolating toxin from Helicobacter pylori. J Biol Chem (1992) 6.54

Helicobacter pylori in health and disease. Gastroenterology (2009) 3.84

The pathogenesis of Helicobacter pylori-induced gastro-duodenal diseases. Annu Rev Pathol (2006) 3.07

Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells. J Clin Invest (2011) 2.77

Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms. Gastroenterology (2008) 2.63

The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria. Immunity (2014) 2.22

Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection. Proc Natl Acad Sci U S A (2002) 2.16

Evolutionary microbial genomics: insights into bacterial host adaptation. Nat Rev Genet (2010) 2.02

Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proc Natl Acad Sci U S A (2004) 1.77

Characterization of the roles of NikR, a nickel-responsive pleiotropic autoregulator of Helicobacter pylori. Mol Microbiol (2003) 1.71

Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis. FEBS J (2011) 1.68

Age of the association between Helicobacter pylori and man. PLoS Pathog (2012) 1.62

Helicobacter pylori perturbs iron trafficking in the epithelium to grow on the cell surface. PLoS Pathog (2011) 1.57

Host response to Helicobacter pylori infection before initiation of the adaptive immune response. FEMS Immunol Med Microbiol (2007) 1.49

Human and Helicobacter pylori coevolution shapes the risk of gastric disease. Proc Natl Acad Sci U S A (2014) 1.48

Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans. J Clin Invest (2012) 1.45

Molecular epidemiology, population genetics, and pathogenic role of Helicobacter pylori. Infect Genet Evol (2011) 1.44

Genome sequence analysis of Helicobacter pylori strains associated with gastric ulceration and gastric cancer. BMC Genomics (2009) 1.42

Gene expression in vivo shows that Helicobacter pylori colonizes an acidic niche on the gastric surface. Proc Natl Acad Sci U S A (2007) 1.42

Ancestral European roots of Helicobacter pylori in India. BMC Genomics (2007) 1.26

The complex methylome of the human gastric pathogen Helicobacter pylori. Nucleic Acids Res (2013) 1.25

Helicobacter pylori virulence factors--one part of a big picture. Lancet (2003) 1.24

Helicobacter pylori infection and related gastrointestinal diseases. J Clin Gastroenterol (2007) 1.23

Genomes of Helicobacter pylori from native Peruvians suggest admixture of ancestral and modern lineages and reveal a western type cag-pathogenicity island. BMC Genomics (2006) 1.23

Natural history of Helicobacter pylori infection. Dig Liver Dis (2008) 1.20

Helicobacter pylori gastritis and gastric MALT-lymphoma. Lancet (1992) 1.17

High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis. Infect Immun (2013) 1.16

Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture. Genome Biol (2002) 1.11

Host-interactive genes in Amerindian Helicobacter pylori diverge from their Old World homologs and mediate inflammatory responses. J Bacteriol (2010) 1.10

Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA. J Bacteriol (2010) 1.06

Helicobacter pylori VacA induces programmed necrosis in gastric epithelial cells. Infect Immun (2011) 1.05

Analysis of hopQ alleles in East Asian and Western strains of Helicobacter pylori. FEMS Microbiol Lett (2005) 1.04

Regulation of gastric B cell recruitment is dependent on IL-17 receptor A signaling in a model of chronic bacterial infection. J Immunol (2009) 1.04

Low-density lipoprotein receptor-related protein-1 (LRP1) mediates autophagy and apoptosis caused by Helicobacter pylori VacA. J Biol Chem (2012) 1.03

Consequences of Helicobacter pylori infection in children. World J Gastroenterol (2010) 1.03

Immune evasion by Helicobacter pylori is mediated by induction of macrophage arginase II. J Immunol (2011) 1.02

Polymorphisms in the intermediate region of VacA impact Helicobacter pylori-induced disease development. J Clin Microbiol (2010) 1.02

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of helicobacter-induced mucosa-associated lymphoid tissue lymphoma. Am J Pathol (2005) 1.00

Methylome diversification through changes in DNA methyltransferase sequence specificity. PLoS Genet (2014) 0.99

Helicobacter pylori exploits cholesterol-rich microdomains for induction of NF-kappaB-dependent responses and peptidoglycan delivery in epithelial cells. Infect Immun (2010) 0.98

Mycoplasma pneumoniae: a reduced-genome intracellular bacterial pathogen. Infect Genet Evol (2003) 0.97

A meta-analysis of interleukin-8 -251 promoter polymorphism associated with gastric cancer risk. PLoS One (2012) 0.96

The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration. PLoS Pathog (2014) 0.96

Phylogeographic origin of Helicobacter pylori determines host-adaptive responses upon coculture with gastric epithelial cells. Infect Immun (2013) 0.95

Point mutations in Helicobacter pylori's fur regulatory gene that alter resistance to metronidazole, a prodrug activated by chemical reduction. PLoS One (2011) 0.94

A mutation burst during the acute phase of Helicobacter pylori infection in humans and rhesus macaques. Nat Commun (2014) 0.94

Disrupted human-pathogen co-evolution: a model for disease. Front Genet (2014) 0.92

A possible link between iron deficiency and gastrointestinal carcinogenesis. Nutr Cancer (2009) 0.91

Genes required for assembly of pili associated with the Helicobacter pylori cag type IV secretion system. Infect Immun (2014) 0.91

Helicobacter pylori genotyping from American indigenous groups shows novel Amerindian vacA and cagA alleles and Asian, African and European admixture. PLoS One (2011) 0.89

Helicobacter pylori and gastric cancer: Indian enigma. World J Gastroenterol (2014) 0.87

S100 calgranulin proteins S100A8, S100A9 and S100A12 are expressed in the inflamed gastric mucosa of Helicobacter pylori-infected children. Can J Gastroenterol (2008) 0.87

Helicobacter pylori and gastric cancer in the Middle East: a new enigma? World J Gastroenterol (2010) 0.87

Transcriptome complexity and riboregulation in the human pathogen Helicobacter pylori. Front Cell Infect Microbiol (2012) 0.86

Evaluation of the relationship between dietary factors, CagA-positive Helicobacter pylori infection, and RUNX3 promoter hypermethylation in gastric cancer tissue. World J Gastroenterol (2013) 0.86

A comprehensive analysis of Helicobacter pylori plasticity zones reveals that they are integrating conjugative elements with intermediate integration specificity. BMC Genomics (2014) 0.85

Evolution of bacterial genes: evidences of positive Darwinian selection and fixation of base substitutions in virulence genes of Helicobacter pylori. Infect Genet Evol (2010) 0.85

Parallel evolution of genome structure and transcriptional landscape in the Epsilonproteobacteria. BMC Genomics (2013) 0.84

Conserved transcriptional unit organization of the cag pathogenicity island among Helicobacter pylori strains. Front Cell Infect Microbiol (2012) 0.84

Analysis of whole genomic expression profiles of Helicobacter pylori related chronic atrophic gastritis with IL-1B-31CC/-511TT genotypes. J Dig Dis (2009) 0.83

Current Paradigm and Future Directions for Treatment of Helicobacter pylori Infection. Curr Treat Options Gastroenterol (2014) 0.82

Helicobacter pylori and gastroesophageal reflux disease. Curr Opin Gastroenterol (2014) 0.82

Whole-genome sequencing of clarithromycin resistant Helicobacter pylori characterizes unidentified variants of multidrug resistant efflux pump genes. Gut Pathog (2014) 0.82

Evolution of amoxicillin resistance of Helicobacter pylori in vitro: characterization of resistance mechanisms. Microb Drug Resist (2014) 0.81

Helicobacter pylori genomic microevolution during naturally occurring transmission between adults. PLoS One (2013) 0.81

Amino acid polymorphisms flanking the EPIYA-A motif of Helicobacter pylori CagA C-terminal region is associated with gastric cancer in east China: experience from a single center. J Dig Dis (2013) 0.80

Pyrosequencing assay to rapidly detect clarithromycin resistance mutations in Canadian Helicobacter pylori isolates. Can J Gastroenterol (2009) 0.79

Resistotype of Helicobacter pylori isolates: the impact on eradication outcome. J Med Microbiol (2014) 0.78

Helicobacter pylori infection in Africa and Europe: enigma of host genetics. Gut (2003) 0.77

Reduced genome size of Helicobacter pylori originating from East Asia. World J Gastroenterol (2014) 0.76

A hydrogen boost for salmonella. Cell Host Microbe (2013) 0.76