PubRank

Roland Nau

Author PubWeight™ 69.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice. Brain 2006 1.63
2 PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation. Infect Immun 2005 1.54
3 Short-term rifampicin pretreatment reduces inflammation and neuronal cell death in a rabbit model of bacterial meningitis. Crit Care Med 2009 1.51
4 Neuronal injury mediated via stimulation of microglial toll-like receptor-9 (TLR9). FASEB J 2003 1.48
5 Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase. Neurobiol Dis 2002 1.28
6 Impairment of mitochondrial calcium handling in a mtSOD1 cell culture model of motoneuron disease. BMC Neurosci 2009 1.26
7 Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone. Antimicrob Agents Chemother 2003 1.25
8 Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis. Infect Immun 2002 1.23
9 Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin. Proc Natl Acad Sci U S A 2007 1.19
10 Toll-like receptor stimulation enhances phagocytosis and intracellular killing of nonencapsulated and encapsulated Streptococcus pneumoniae by murine microglia. Infect Immun 2009 1.18
11 Dose-dependent activation of microglial cells by Toll-like receptor agonists alone and in combination. J Neuroimmunol 2004 1.16
12 Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures. J Neurochem 2005 1.14
13 PavB is a surface-exposed adhesin of Streptococcus pneumoniae contributing to nasopharyngeal colonization and airways infections. Mol Microbiol 2010 1.14
14 Cerebrospinal fluid findings in adults with acute Lyme neuroborreliosis. J Neurol 2011 1.12
15 Mechanisms of injury in bacterial meningitis. Curr Opin Neurol 2010 1.11
16 Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia. Glia 2012 1.08
17 Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells. Infect Immun 2008 1.04
18 Varicella zoster virus cerebellitis in a 66-year-old patient without herpes zoster. Lancet 2006 1.01
19 Differential regulation of Toll-like receptor mRNAs in experimental murine central nervous system infections. Neurosci Lett 2003 0.99
20 Serum concentrations of activin and follistatin are elevated and run in parallel in patients with septicemia. Eur J Endocrinol 2003 0.99
21 Intrathecal antibody production against Epstein-Barr and other neurotropic viruses in pediatric and adult onset multiple sclerosis. J Neurol 2009 0.98
22 Matrix metalloproteinase-9 deficiency impairs host defense mechanisms against Streptococcus pneumoniae in a mouse model of bacterial meningitis. Neurosci Lett 2003 0.97
23 Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes. Infect Immun 2013 0.96
24 Ly-6G+CCR2- myeloid cells rather than Ly-6ChighCCR2+ monocytes are required for the control of bacterial infection in the central nervous system. J Immunol 2008 0.93
25 Rapid microtubule bundling and stabilization by the Streptococcus pneumoniae neurotoxin pneumolysin in a cholesterol-dependent, non-lytic and Src-kinase dependent manner inhibits intracellular trafficking. Mol Microbiol 2008 0.92
26 Increased activin levels in cerebrospinal fluid of rabbits with bacterial meningitis are associated with activation of microglia. J Neurochem 2003 0.92
27 Streptococcus pneumoniae Infection aggravates experimental autoimmune encephalomyelitis via Toll-like receptor 2. Infect Immun 2006 0.91
28 Toll-like receptor stimulation increases phagocytosis of Cryptococcus neoformans by microglial cells. J Neuroinflammation 2013 0.89
29 Increased expression of BDNF and proliferation of dentate granule cells after bacterial meningitis. J Neuropathol Exp Neurol 2005 0.88
30 Fibronectin is elevated in the cerebrospinal fluid of patients suffering from bacterial meningitis and enhances inflammation caused by bacterial products in primary mouse microglial cell cultures. J Neurochem 2007 0.87
31 Increased mortality and spatial memory deficits in TNF-alpha-deficient mice in ceftriaxone-treated experimental pneumococcal meningitis. Neurobiol Dis 2004 0.86
32 Immune response to capsular polysaccharide and surface proteins of Streptococcus pneumoniae in patients with invasive pneumococcal disease. J Infect Dis 2002 0.86
33 Increased neurogenesis after experimental Streptococcus pneumoniae meningitis. J Neurosci Res 2003 0.85
34 Stimulation of Toll-like receptor 9 by chronic intraventricular unmethylated cytosine-guanine DNA infusion causes neuroinflammation and impaired spatial memory. J Neuropathol Exp Neurol 2009 0.85
35 Pharmacodynamics of antibiotics with respect to bacterial killing of and release of lipoteichoic acid by Streptococcus pneumoniae. J Antimicrob Chemother 2005 0.85
36 Systemic infections in multiple sclerosis and experimental autoimmune encephalomyelitis. Arch Physiol Biochem 2007 0.84
37 Experimental pneumococcal meningitis: impaired clearance of bacteria from the blood due to increased apoptosis in the spleen in Bcl-2-deficient mice. Infect Immun 2004 0.84
38 Rifampin followed by ceftriaxone for experimental meningitis decreases lipoteichoic acid concentrations in cerebrospinal fluid and reduces neuronal damage in comparison to ceftriaxone alone. Antimicrob Agents Chemother 2003 0.84
39 Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone. J Neurochem 2004 0.84
40 Dexamethasone increases hippocampal neuronal apoptosis in a rabbit model of Escherichia coli meningitis. Pediatr Res 2006 0.84
41 Increased neurogenesis after hypoxic-ischemic encephalopathy in humans is age related. Acta Neuropathol 2009 0.84
42 Additive microglia-mediated neuronal injury caused by amyloid-β and bacterial TLR agonists in murine neuron-microglia co-cultures quantified by an automated image analysis using cognition network technology. J Alzheimers Dis 2012 0.83
43 Intrauterine exposure to dexamethasone impairs proliferation but not neuronal differentiation in the dentate gyrus of newborn common marmoset monkeys. Brain Pathol 2006 0.83
44 Frequency of dementia syndromes with a potentially treatable cause in geriatric in-patients: analysis of a 1-year interval. Eur Arch Psychiatry Clin Neurosci 2015 0.82
45 Recurrent systemic infections with Streptococcus pneumoniae do not aggravate the course of experimental neurodegenerative diseases. J Neurosci Res 2010 0.82
46 No long-term effect two years after intrauterine exposure to dexamethasone on dentate gyrus volume, neuronal proliferation and differentiation in common marmoset monkeys. Brain Pathol 2008 0.82
47 The viral TLR3 agonist poly(I:C) stimulates phagocytosis and intracellular killing of Escherichia coli by microglial cells. Neurosci Lett 2010 0.82
48 Enriched environment fails to increase meningitis-induced neurogenesis and spatial memory in a mouse model of pneumococcal meningitis. J Neurosci Res 2009 0.81
49 Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage. PLoS Pathog 2013 0.81
50 Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury. BMC Infect Dis 2007 0.81
51 Protein synthesis inhibiting clindamycin improves outcome in a mouse model of Staphylococcus aureus sepsis compared with the cell wall active ceftriaxone. Crit Care Med 2002 0.81
52 Activin A concentrations in human cerebrospinal fluid are age-dependent and elevated in meningitis. J Neurol Sci 2006 0.81
53 Contribution of capsular and clonal types and beta-lactam resistance to the severity of experimental pneumococcal meningitis. Microbes Infect 2007 0.81
54 Overton's rule helps to estimate the penetration of anti-infectives into patients' cerebrospinal fluid. Antimicrob Agents Chemother 2011 0.80
55 Pre-infection physical exercise decreases mortality and stimulates neurogenesis in bacterial meningitis. J Neuroinflammation 2012 0.80
56 Fibronectin stimulates Escherichia coli phagocytosis by microglial cells. Glia 2010 0.79
57 Antiinflammatory but no neuroprotective effects of melatonin under clinical treatment conditions in rabbit models of bacterial meningitis. J Neurosci Res 2006 0.79
58 Long-term intrathecal infusion of outer surface protein C from Borrelia burgdorferi causes axonal damage. J Neuropathol Exp Neurol 2011 0.79
59 The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in microglial cells. J Neuroimmunol 2012 0.79
60 Microglial cells and peritoneal macrophages release activin A upon stimulation with Toll-like receptor agonists. Neurosci Lett 2006 0.79
61 Multivalent choline dendrimers increase phagocytosis of Streptococcus pneumoniae R6 by microglial cells. Chemotherapy 2013 0.79
62 Role of activin in bacterial infections: a potential target for immunointervention? Immunotherapy 2010 0.78
63 Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 and Streptococcus pneumoniae R6 by microglial cells. J Neuroimmunol 2012 0.78
64 Modulation of hippocampal neuroplasticity by Fas/CD95 regulatory protein 2 (Faim2) in the course of bacterial meningitis. J Neuropathol Exp Neurol 2014 0.78
65 Absence of Streptococcus pneumoniae in pharyngeal swabs of geriatric inpatients. Infect Dis (Lond) 2015 0.78
66 Vitamin d deficiency reduces the immune response, phagocytosis rate, and intracellular killing rate of microglial cells. Infect Immun 2014 0.77
67 Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection. J Neuroinflammation 2014 0.77
68 No neuroprotective effect of erythropoietin under clinical treatment conditions in a rabbit model of Escherichia coli meningitis. Pediatr Res 2007 0.77
69 Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections. J Neuroinflammation 2014 0.77
70 Differences in clinical manifestation of Streptococcus pneumoniae infection are not correlated with in vitro production and release of the virulence factors pneumolysin and lipoteichoic and teichoic acids. J Clin Microbiol 2004 0.77
71 Comparison of the probability of target attainment between ceftriaxone and cefepime in the cerebrospinal fluid and serum against Streptococcus pneumoniae. Diagn Microbiol Infect Dis 2007 0.76
72 Limited protection of TAT-Bcl-X(L) against pneumolysin-induced neuronal cell death. Neurosci Lett 2005 0.76
73 Melatonin is neuroprotective in experimental Streptococcus pneumoniae meningitis. J Infect Dis 2005 0.76
74 Follistatin does not influence the course of Escherichia coli K1 sepsis in a mouse model. Shock 2012 0.76
75 Unilateral phrenic nerve lesion in Lyme neuroborreliosis. BMC Pulm Med 2013 0.75
76 Minocycline delays but does not attenuate the course of experimental autoimmune encephalomyelitis in Streptococcus pneumoniae-infected mice. J Antimicrob Chemother 2006 0.75
77 Moxifloxacin in experimental Streptococcus pneumoniae cerebritis and meningitis. Neurocrit Care 2005 0.75
78 Bacterial contamination and the transport vial material affect cerebrospinal fluid concentrations of β-Amyloid and Tau protein as determined by enzyme immunoassay. Dement Geriatr Cogn Disord 2011 0.75
79 Influence of subinhibitory concentrations of protein-synthesis-inhibiting antibiotics on production and release of the pneumococcal virulence factor pneumolysin in vitro. Chemotherapy 2007 0.75
80 Fungal encephalitis in human autopsy cases is associated with extensive neuronal damage but only minimal repair. Neuropathol Appl Neurobiol 2014 0.75
81 Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism. Glia 2015 0.75
82 The use of S100B and Tau protein concentrations in the cerebrospinal fluid for the differential diagnosis of bacterial meningitis: a retrospective analysis. Eur Neurol 2011 0.75
83 Intrathecal treatment with the anti-phosphorylcholine monoclonal antibody TEPC-15 decreases neuronal damage in experimental pneumococcal meningitis. Chemotherapy 2012 0.75