2-methoxyestradiol induces vasodilation by stimulating NO release via PPARγ/PI3K/Akt pathway.

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🔗 View Article (PMC 4351983)

Published in PLoS One on March 06, 2015

Authors

Weiyu Chen1, Yuhong Cui2, Shuhui Zheng3, Jinghe Huang4, Ping Li2, Tommaso Simoncini5, Yongfu Zhang6, Xiaodong Fu2

Author Affiliations

1: School of Basic Sciences, Guangzhou Medical University, Guangzhou, 510182, Guangdong Province, China; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, Guangdong Province, China.
2: School of Basic Sciences, Guangzhou Medical University, Guangzhou, 510182, Guangdong Province, China.
3: Research Center of Translational Medicine, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, Guangdong Province, China.
4: Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, Guangdong Province, China.
5: Molecular and Cellular Gynecological Endocrinology Laboratory (MCGEL), Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, 56100, Italy.
6: Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou, 510180, Guangdong Province, China.

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