Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset.

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Published in PLoS Pathog on March 24, 2015

Authors

Krista E van Meijgaarden1, Mariëlle C Haks1, Nadia Caccamo2, Francesco Dieli2, Tom H M Ottenhoff1, Simone A Joosten1

Author Affiliations

1: Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
2: Central Laboratory for Advanced Diagnostic and Biomedical Research (CLADIBIOR), Dipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Università di Palermo, Palermo, Italy.

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