Reflections on immune checkpoint inhibition in non-small cell lung cancer.

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🔗 View Article (PMC 4367678)

Published in Transl Lung Cancer Res on December 01, 2014

Authors

Konstantinos Leventakos1, Aaron S Mansfield1

Author Affiliations

1: Division of Medical Oncology, Mayo Clinic, Rochester, MN, USA.

Associated clinical trials:

Safety Study of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumors | NCT01968109

Study of Two Doses of MK-3475 (Pembrolizumab) Versus Docetaxel in Previously-Treated Participants With Non-Small Cell Lung Cancer (MK-3475-010/KEYNOTE-010) | NCT01905657

An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026) | NCT02041533

Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab or Pembrolizumab Therapy | NCT01789827