N (1)-Fluoroalkyltryptophan Analogues: Synthesis and in vitro Study as Potential Substrates for Indoleamine 2,3-Dioxygenase.

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Published in ACS Med Chem Lett on January 25, 2015

Authors

Jean Henrottin1, Astrid Zervosen2, Christian Lemaire2, Frédéric Sapunaric2, Sophie Laurent2, Benoit Van den Eynde3, Serge Goldman4, Alain Plenevaux2, André Luxen2

Author Affiliations

1: Cyclotron Research Center, Department of Chemistry, and Macromolécules Biologiques, Center for Protein Engineering, Université de Liège, Sart-Tilman , B-4000 Liège, Belgium ; Cyclotron Research Center, Department of Chemistry, and Macromolécules Biologiques, Center for Protein Engineering, Université de Liège, Sart-Tilman , B-4000 Liège, Belgium.
2: Cyclotron Research Center, Department of Chemistry, and Macromolécules Biologiques, Center for Protein Engineering, Université de Liège, Sart-Tilman , B-4000 Liège, Belgium.
3: Ludwig Institute for Cancer Research, Brussels Branch and de Duve Institute, Université Catholique de Louvain , B-1200 Brussels, Belgium.
4: PET/Biomedical Cyclotron Unit and Department of Nuclear Medicine, Erasme Hospital, Université Libre de Bruxelles , B-1070 Brussels, Belgium ; Center for Microscopy and Molecular Imaging , Rue Adrienne Bolland 8, B-6041 Gosselies, Belgium.

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