Janet D Siliciano

Author PubWeight™ 56.76‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell 2013 6.47
2 Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells. J Virol 2006 5.41
3 Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors. J Virol 2006 4.27
4 Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. PLoS Pathog 2013 4.05
5 Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol 2004 3.17
6 Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo. J Virol 2003 2.78
7 Experimental approaches to the study of HIV-1 latency. Nat Rev Microbiol 2007 2.71
8 Kinetics of human immunodeficiency virus type 1 decay following entry into resting CD4+ T cells. J Virol 2005 2.55
9 Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. J Virol 2011 2.18
10 Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough. Cell Host Microbe 2008 2.08
11 Rapid quantification of the latent reservoir for HIV-1 using a viral outgrowth assay. PLoS Pathog 2013 2.02
12 Identification of nevirapine-resistant HIV-1 in the latent reservoir after single-dose nevirapine to prevent mother-to-child transmission of HIV-1. J Infect Dis 2009 1.93
13 Analysis of human immunodeficiency virus type 1 viremia and provirus in resting CD4+ T cells reveals a novel source of residual viremia in patients on antiretroviral therapy. J Virol 2009 1.89
14 The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation. J Biol Chem 2008 1.83
15 Limits on replenishment of the resting CD4+ T cell reservoir for HIV in patients on HAART. PLoS Pathog 2007 1.81
16 Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations. J Clin Invest 2015 1.76
17 Role of APOBEC3G/F-mediated hypermutation in the control of human immunodeficiency virus type 1 in elite suppressors. J Virol 2007 1.47
18 A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy. Clin Infect Dis 2013 1.46
19 No evidence for decay of the latent reservoir in HIV-1-infected patients receiving intensive enfuvirtide-containing antiretroviral therapy. J Infect Dis 2010 1.45
20 Influence of host gene transcription level and orientation on HIV-1 latency in a primary-cell model. J Virol 2011 1.34
21 HIV-1 DNA is detected in bone marrow populations containing CD4+ T cells but is not found in purified CD34+ hematopoietic progenitor cells in most patients on antiretroviral therapy. J Infect Dis 2012 1.29
22 Consistent inhibition of HIV-1 replication in CD4+ T cells by acyclovir without detection of human herpesviruses. J Virol 2011 0.88
23 Recent developments in the effort to cure HIV infection: going beyond N = 1. J Clin Invest 2016 0.85
24 Sensitivity of V75I HIV-1 reverse transcriptase mutant selected in vitro by acyclovir to anti-HIV drugs. AIDS 2010 0.85
25 Residual plasma viraemia and infectious HIV-1 recovery from resting memory CD4 cells in patients on antiretroviral therapy: results from ACTG A5173. Antivir Ther 2013 0.83
26 An anti-CD45RO immunotoxin kills latently infected human immunodeficiency virus (HIV) CD4 T cells in the blood of HIV-positive persons. J Infect Dis 2002 0.81
27 The Effect of early treatment on the latent reservoir of HIV-1. J Infect Dis 2005 0.76