Fast eQTL Analysis for Twin Studies.

PubWeight™: 0.76‹?›

🔗 View Article (PMID 25865703)

Published in Genet Epidemiol on April 10, 2015

Authors

Zhaoyu Yin1, Kai Xia2, Wonil Chung3, Patrick F Sullivan4, Fei Zou1

Author Affiliations

1: Department of Biostatistics, University of North Carolina, Chapel Hill, North, Carolina, United States of America.
2: Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina, United States of America.
3: School of Public Health, Harvard, Boston, Massachusetts, United States of America.
4: Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, United States of America.

Articles cited by this

Precision mapping of quantitative trait loci. Genetics (1994) 32.57

Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet (2010) 10.75

OpenMx: An Open Source Extended Structural Equation Modeling Framework. Psychometrika (2011) 8.25

Genome-wide association studies: potential next steps on a genetic journey. Hum Mol Genet (2008) 7.54

Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies. PLoS Genet (2008) 6.66

Heritability of adult body height: a comparative study of twin cohorts in eight countries. Twin Res (2003) 6.43

Revealing the architecture of gene regulation: the promise of eQTL studies. Trends Genet (2008) 5.78

Classical twin studies and beyond. Nat Rev Genet (2002) 4.81

Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies. Bioinformatics (2010) 4.56

Matrix eQTL: ultra fast eQTL analysis via large matrix operations. Bioinformatics (2012) 4.28

Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81

Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes. PLoS Genet (2010) 3.75

Accurate discovery of expression quantitative trait loci under confounding from spurious and genuine regulatory hotspots. Genetics (2008) 3.66

A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies. PLoS Comput Biol (2010) 3.23

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet (2010) 2.43

Regression models for twin studies: a critical review. Int J Epidemiol (2005) 2.24

Heritability and genomics of gene expression in peripheral blood. Nat Genet (2014) 2.00

Meta-analysis of genome-wide association studies with overlapping subjects. Am J Hum Genet (2009) 1.83

High-resolution mapping of gene expression using association in an outbred mouse stock. PLoS Genet (2008) 1.72

The association between fat and lean mass and bone mineral density: the Healthy Twin Study. Bone (2012) 1.61

A review of statistical methods for expression quantitative trait loci mapping. Mamm Genome (2006) 1.60

Detection and interpretation of expression quantitative trait loci (eQTL). Methods (2009) 1.48

Biometrical modeling of twin and family data using standard mixed model software. Biometrics (2007) 1.46

Expression quantitative trait loci mapping with multivariate sparse partial least squares regression. Genetics (2009) 1.37

Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain. Neurobiol Dis (2012) 1.35

An efficient resampling method for assessing genome-wide statistical significance in mapping quantitative trait Loci. Genetics (2004) 1.32

Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study. Biol Psychiatry (2008) 1.27

eQTL Viewer: visualizing how sequence variation affects genome-wide transcription. BMC Bioinformatics (2007) 1.25

Heritability of performance deficit accumulation during acute sleep deprivation in twins. Sleep (2012) 1.22

Mapping genetic influences on ventricular structure in twins. Neuroimage (2008) 1.22

Fitting genetic models with LISREL: hypothesis testing. Behav Genet (1989) 1.17

Analysis of twin data using SAS. Biometrics (2008) 1.13

A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes. Diabetes (2013) 1.04

Bayesian detection of expression quantitative trait loci hot spots. Genetics (2011) 1.00

Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma. Hum Genet (2011) 0.99

Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2. Mol Psychiatry (2013) 0.99

Statistical inference in mixed models and analysis of twin and family data. Biometrics (2011) 0.97

Computational tools for discovery and interpretation of expression quantitative trait loci. Pharmacogenomics (2012) 0.80