Anti-Yo antibody uptake and interaction with its intracellular target antigen causes Purkinje cell death in rat cerebellar slice cultures: a possible mechanism for paraneoplastic cerebellar degeneration in humans with gynecological or breast cancers.

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Published in PLoS One on April 17, 2015

Authors

John E Greenlee1, Susan A Clawson2, Kenneth E Hill2, Blair Wood2, Stacey L Clardy1, Ikuo Tsunoda3, Noel G Carlson4

Author Affiliations

1: Neurology Service, George E. Wahlen Veterans Affairs Health Care System, Salt Lake City, Utah, United States of America; Department of Neurology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.
2: Department of Neurology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.
3: Department of Microbiology and Immunology Center for Molecular and Tumor Virology (CMTV), Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States of America.
4: Department of Neurology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America; Geriatric Research, Education, and Care Center (GRECC), George E. Wahlen Veterans Affairs Health Care System, Salt Lake City, Utah, United States of America; Research Service, George E. Wahlen Veterans Affairs Health Care System, Salt Lake City, Utah, United States of America; Department of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.

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