Published in Crit Care on February 27, 2015
The Gravity-VAP (Ventilator-Associated Pneumonia) Trial (Gravity-VAP) | NCT01138540
Bacterial biofilms: a common cause of persistent infections. Science (1999) 40.82
Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med (2005) 23.85
Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial. Lancet (1999) 6.38
Antibiotic resistance of bacterial biofilms. Int J Antimicrob Agents (2010) 5.18
The EPS matrix: the "house of biofilm cells". J Bacteriol (2007) 3.38
Positive-end expiratory pressure reduces incidence of ventilator-associated pneumonia in nonhypoxemic patients. Crit Care Med (2008) 2.87
Nosocomial bronchopneumonia in the critically ill. Histologic and bacteriologic aspects. Am Rev Respir Dis (1992) 2.55
Endotracheal tube intraluminal volume loss among mechanically ventilated patients. Crit Care Med (2004) 2.20
Recruitment and derecruitment during acute respiratory failure: an experimental study. Am J Respir Crit Care Med (2001) 2.12
Bacterial colonization of the respiratory tract following tracheal intubation-effect of gravity: an experimental study. Crit Care Med (2003) 2.11
Implications of endotracheal tube biofilm for ventilator-associated pneumonia. Intensive Care Med (1999) 1.86
Microorganism identification by mass spectrometry and protein database searches. Anal Chem (1999) 1.84
Silver-coated endotracheal tubes associated with reduced bacterial burden in the lungs of mechanically ventilated dogs. Chest (2002) 1.63
Pulmonary aspiration of gastric contents in patients receiving mechanical ventilation: the effect of body position. Ann Intern Med (1992) 1.60
A clinical assessment of the Mucus Shaver: a device to keep the endotracheal tube free from secretions. Crit Care Med (2012) 1.57
Effects of duty cycle and positive end-expiratory pressure on mucus clearance during mechanical ventilation*. Crit Care Med (2012) 1.52
Tracheal tube biofilm as a source of bacterial colonization of the lung. J Clin Microbiol (1989) 1.46
Effects of tracheal orientation on development of ventilator-associated pneumonia: an experimental study. Intensive Care Med (2012) 1.45
A European care bundle for prevention of ventilator-associated pneumonia. Intensive Care Med (2010) 1.40
The immune system vs. Pseudomonas aeruginosa biofilms. FEMS Immunol Med Microbiol (2010) 1.38
Nosocomial pulmonary infection: possible etiologic significance of bacterial adhesion to endotracheal tubes. Crit Care Med (1986) 1.30
Nosocomial pneumonia in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med (1998) 1.22
Multicenter prospective study of ventilator-associated pneumonia during acute respiratory distress syndrome. Incidence, prognosis, and risk factors. ARDS Study Group. Am J Respir Crit Care Med (2000) 1.17
Implications of endotracheal tube biofilm in ventilator-associated pneumonia response: a state of concept. Crit Care (2012) 1.14
Automatic regulation of the cuff pressure in endotracheally-intubated patients. Eur Respir J (2002) 1.09
Following tracheal intubation, mucus flow is reversed in the semirecumbent position: possible role in the pathogenesis of ventilator-associated pneumonia. Crit Care Med (2008) 1.07
Endotracheal tubes coated with antiseptics decrease bacterial colonization of the ventilator circuits, lungs, and endotracheal tube. Anesthesiology (2004) 0.99
Eradication of endotracheal tube biofilm by nebulised gentamicin. Intensive Care Med (2002) 0.96
Structural features of tracheal tube biofilm formed during prolonged mechanical ventilation. Chest (1995) 0.93
Selective decontamination of the digestive tract (SDD) does not prevent the formation of microbial biofilms on endotracheal tubes. J Antimicrob Chemother (1993) 0.90
A novel porcine model of ventilator-associated pneumonia caused by oropharyngeal challenge with Pseudomonas aeruginosa. Anesthesiology (2014) 0.90
Evidence for dynamic phenomena in residual tracheal tube biofilm. Br J Anaesth (1993) 0.85
Experimental severe Pseudomonas aeruginosa pneumonia and antibiotic therapy in piglets receiving mechanical ventilation. Chest (2007) 0.84
Advanced endotracheal tube biofilm stage, not duration of intubation, is related to pneumonia. J Trauma Acute Care Surg (2012) 0.82
Direct analysis of bacterial viability in endotracheal tube biofilm from a pig model of methicillin-resistant Staphylococcus aureus pneumonia following antimicrobial therapy. FEMS Immunol Med Microbiol (2012) 0.81
Dissemination of respiratory secretions during tracheal tube suctioning in an intensive care unit. Ann Acad Med Singapore (1999) 0.81
Linezolid limits burden of methicillin-resistant Staphylococcus aureus in biofilm of tracheal tubes. Crit Care Med (2012) 0.80
Gravity predominates over ventilatory pattern in the prevention of ventilator-associated pneumonia. Crit Care Med (2014) 0.78
Effect of mechanical cleaning of endotracheal tubes with sterile urethral catheters to reduce biofilm formation in ventilator patients. Pediatr Crit Care Med (2013) 0.77
Removal of endotracheal tube obstruction with a secretion clearance device. Respir Care (2013) 0.77