Published in Arthritis Rheumatol on May 01, 2015
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IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest (1999) 7.66
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The risk of infections with biologic therapies for rheumatoid arthritis. Semin Arthritis Rheum (2008) 2.42
Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies. J Clin Invest (2007) 2.37
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Reciprocal activation of CD4+ T cells and synovial fibroblasts by stromal cell-derived factor 1 promotes RANKL expression and osteoclastogenesis in rheumatoid arthritis. Arthritis Rheumatol (2014) 1.53
An HLA-DRB1-coded signal transduction ligand facilitates inflammatory arthritis: a new mechanism of autoimmunity. J Immunol (2012) 1.48
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Thrombospondin mediates focal adhesion disassembly through interactions with cell surface calreticulin. J Biol Chem (2000) 1.46
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The association between periodontal disease and joint destruction in rheumatoid arthritis extends the link between the HLA-DR shared epitope and severity of bone destruction. Ann Rheum Dis (2005) 1.38
Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells. J Immunol (2000) 1.38
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Independent association of rheumatoid factor and the HLA-DRB1 shared epitope with radiographic outcome in rheumatoid arthritis. Arthritis Rheum (2001) 1.17
Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus. J Rheumatol (2007) 1.12
The rheumatoid arthritis shared epitope triggers innate immune signaling via cell surface calreticulin. J Immunol (2007) 1.09
Association of circulating adiponectin levels with progression of radiographic joint destruction in rheumatoid arthritis. Ann Rheum Dis (2011) 1.08
"Homozygosity" for the HLA-DR shared epitope contributes the highest risk for rheumatoid arthritis concordance in identical twins. Arthritis Rheum (1994) 1.07
A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis. Arthritis Res Ther (2011) 1.05
Adiponectin induces dendritic cell activation via PLCγ/JNK/NF-κB pathways, leading to Th1 and Th17 polarization. J Immunol (2012) 1.02
Activation of nitric oxide signaling by the rheumatoid arthritis shared epitope. Arthritis Rheum (2006) 1.01
Immune dysregulation by the rheumatoid arthritis shared epitope. J Immunol (2010) 1.00
The rheumatoid arthritis shared epitope increases cellular susceptibility to oxidative stress by antagonizing an adenosine-mediated anti-oxidative pathway. Arthritis Res Ther (2007) 0.99
Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling. Arthritis Rheum (2013) 0.96
Tumor necrosis factor-inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor-driven model of rheumatoid arthritis. Arthritis Rheum (2013) 0.96
MHC molecules in health and disease: At the cusp of a paradigm shift. Self Nonself (2011) 0.94
Deficiency of thrombospondin-1 reduces Th17 differentiation and attenuates experimental autoimmune encephalomyelitis. J Autoimmun (2009) 0.93
Identification of the rheumatoid arthritis shared epitope binding site on calreticulin. PLoS One (2010) 0.92
Important role of interleukin-3 in the early phase of collagen-induced arthritis. Arthritis Rheum (2009) 0.92
Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice. J Immunol (2004) 0.91
A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis. Arthritis Res Ther (2010) 0.91
Rheumatoid arthritis: understanding joint damage and physical disability in RA. Nat Rev Rheumatol (2011) 0.88
The axis of thrombospondin-1, transforming growth factor beta and connective tissue growth factor: an emerging therapeutic target in rheumatoid arthritis. Curr Vasc Pharmacol (2010) 0.88
Early activation of invariant natural killer T cells in a rheumatoid arthritis model and application to disease treatment. Immunology (2010) 0.86
The quest for better understanding of HLA-disease association: scenes from a road less travelled by. Discov Med (2013) 0.85
Adiponectin in metabolic bone disease. Curr Med Chem (2012) 0.85
Developing potent backbone cyclic peptides bearing the shared epitope sequence as rheumatoid arthritis drug-leads. Bioorg Med Chem Lett (2011) 0.84
Disease mechanisms in rheumatoid arthritis: gene dosage effect of HLA-DR haplotypes. J Lab Clin Med (1994) 0.83
Novel method for the synthesis of urea backbone cyclic peptides using new Alloc-protected glycine building units. J Pept Sci (2010) 0.81
A small shared epitope-mimetic compound potently accelerates osteoclast-mediated bone damage in autoimmune arthritis. J Immunol (2013) 0.81
Osteoclasts in RA: diverse origins and functions. Joint Bone Spine (2013) 0.81
Thrombospondin promotes resorption by osteoclasts in vitro. Biochem Biophys Res Commun (1995) 0.81
Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor β-chain. Arthritis Res Ther (2010) 0.79