Published in Glycobiology on April 21, 2015
Demonstration of peptide:N-glycosidase F activity in endo-beta-N-acetylglucosaminidase F preparations. J Biol Chem (1984) 3.26
Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway. Genet Med (2014) 2.57
When the message goes awry: disease-producing mutations that influence mRNA content and performance. Cell (2001) 2.55
A role for N-glycanase in the cytosolic turnover of glycoproteins. EMBO J (2003) 2.18
PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase. J Cell Biol (2000) 1.98
A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised. EMBO J (2004) 1.53
Sense from nonsense: therapies for premature stop codon diseases. Trends Mol Med (2012) 1.43
Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover. Chem Biol (2004) 1.42
A cell-based high-content screening assay reveals activators and inhibitors of cancer cell invasion. Sci Signal (2011) 1.20
Yeast N-glycanase distinguishes between native and non-native glycoproteins. EMBO Rep (2004) 1.18
Demonstration of a new amidase acting on glycopeptides. Biochem Biophys Res Commun (1977) 1.17
DDOST mutations identified by whole-exome sequencing are implicated in congenital disorders of glycosylation. Am J Hum Genet (2012) 1.09
The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem Biophys Res Commun (2001) 1.08
The PUB domain functions as a p97 binding module in human peptide N-glycanase. J Biol Chem (2006) 1.08
A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins. Proc Natl Acad Sci U S A (2004) 1.04
Processing of a class I-restricted epitope from tyrosinase requires peptide N-glycanase and the cooperative action of endoplasmic reticulum aminopeptidase 1 and cytosolic proteases. J Immunol (2006) 1.03
Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module. Proc Natl Acad Sci U S A (2006) 1.01
Cytoplasmic peptide:N-glycanase and catabolic pathway for free N-glycans in the cytosol. Semin Cell Dev Biol (2007) 0.98
A plant peptide: N-glycanase orthologue facilitates glycoprotein ER-associated degradation in yeast. Biochim Biophys Acta (2012) 0.97
N-linked glycosylation does not impair proteasomal degradation but affects class I major histocompatibility complex presentation. J Biol Chem (2007) 0.93
NGLY1 mutation causes neuromotor impairment, intellectual disability, and neuropathy. Eur J Med Genet (2014) 0.91
Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation. Proc Natl Acad Sci U S A (2013) 0.90
Evidence for an essential deglycosylation-independent activity of PNGase in Drosophila melanogaster. PLoS One (2010) 0.86
Molecular identification and characterization of peptide: N-glycanase from Schizosaccharomyces pombe. Biochem Biophys Res Commun (2008) 0.85