Checkpoint modulation--A new way to direct the immune system against renal cell carcinoma.

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Published in Hum Vaccin Immunother on January 01, 2015

Authors

Jens Bedke1, Stephan Kruck, Georgios Gakis, Arnulf Stenzl, Peter J Goebell

Author Affiliations

1: a Department of Urology; Eberhard Karls University ; Tübingen , Germany.

Associated clinical trials:

A Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent Malignancies (MDX1106-03) | NCT00730639

Multiple Ascending Dose (MDX1105-01) (Anti-PDL1) | NCT00729664

Study of Nivolumab (BMS-936558) vs. Everolimus in Pre-Treated Advanced or Metastatic Clear-cell Renal Cell Carcinoma (CheckMate 025) | NCT01668784

Phase 3 Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (RCC) (ADAPT) | NCT01582672

IMA901 in Patients Receiving Sunitinib for Advanced/Metastatic Renal Cell Carcinoma | NCT01265901

Nivolumab Combined With Ipilimumab Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (CheckMate 214) | NCT02231749

IMP321 Phase 1 Trial in Metastatic Renal Cell Carcinoma (MRCC) | NCT00351949

Monoclonal Antibody Therapy in Treating Patients With Metastatic Renal Cell Cancer | NCT00057889

Dose-Finding Study Of CP-675,206 And SU011248 In Patients With Metastatic Renal Cell Carcinoma | NCT00372853

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