Functional Beta2-Integrins Restrict Skin Inflammation In Vivo.

Leukocyte arrest: Biomechanics and molecular mechanisms of β2 integrin activation. Biorheology (2015) 0.87

Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation. PLoS One (2015) 0.76

Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med (2008) 4.55

Deciphering the transcriptional network of the dendritic cell lineage. Nat Immunol (2012) 4.17

Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells. Nat Med (2009) 2.85

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation. Nat Med (2009) 2.51

Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens. Immunity (2011) 2.39

A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans. Nat Med (2009) 2.31

Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin. Immunity (2013) 2.20

Defective neutrophil recruitment in leukocyte adhesion deficiency type I disease causes local IL-17-driven inflammatory bone loss. Sci Transl Med (2014) 1.94

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood (2012) 1.64

Absence of CCR4 exacerbates skin inflammation in an oxazolone-induced contact hypersensitivity model. J Invest Dermatol (2010) 1.51

The molecular basis of leukocyte recruitment and its deficiencies. Mol Immunol (2012) 1.30

Active MAC-1 (CD11b/CD18) on DCs inhibits full T-cell activation. Blood (2006) 1.23

Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells. J Clin Invest (2002) 1.18

Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils. Nat Immunol (2008) 1.16

Reversion mutations in patients with leukocyte adhesion deficiency type-1 (LAD-1). Blood (2007) 1.09

Integrin CD11b negatively regulates TLR9-triggered dendritic cell cross-priming by upregulating microRNA-146a. J Immunol (2012) 1.04

LFA-1 activity state on dendritic cells regulates contact duration with T cells and promotes T-cell priming. Blood (2010) 1.02

Genetic etiologies of leukocyte adhesion defects. Curr Opin Immunol (2009) 1.01

The β2 integrin-kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo. Blood (2013) 0.95

The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow. J Biol Chem (2013) 0.88

Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype. Nat Commun (2014) 0.87

The integrin coactivator Kindlin-3 is not required for lymphocyte diapedesis. Blood (2013) 0.86