Published in Curr Osteoporos Rep on August 01, 2015
The molecular mechanisms of hemodialysis vascular access failure. Kidney Int (2016) 0.84
Label-Free Quantitative Proteomics Reveals Differences in Molecular Mechanism of Atherosclerosis Related and Non-Related to Chronic Kidney Disease. Int J Mol Sci (2016) 0.80
Cystathionine γ-Lyase-Hydrogen Sulfide Induces Runt-Related Transcription Factor 2 Sulfhydration, Thereby Increasing Osteoblast Activity to Promote Bone Fracture Healing. Antioxid Redox Signal (2017) 0.76
Aortic calcification burden predicts deterioration of renal function after radical nephrectomy. BMC Urol (2017) 0.75
Clinical relevance of aortic calcification in urolithiasis patients. BMC Urol (2017) 0.75
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell (1997) 18.91
Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med (2009) 13.57
Progress and challenges in translating the biology of atherosclerosis. Nature (2011) 9.41
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev (1998) 7.81
Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. Kidney Int (2007) 6.34
Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant (2003) 6.15
Definition, evaluation, and classification of renal osteodystrophy: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int (2006) 5.69
Relation between serum phosphate level and cardiovascular event rate in people with coronary disease. Circulation (2005) 5.29
Phosphate regulation of vascular smooth muscle cell calcification. Circ Res (2000) 5.18
Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res (2006) 3.97
The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification. J Clin Invest (2003) 3.71
Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study. Lancet (2003) 3.70
Aortic calcification and the risk of osteoporosis and fractures. J Clin Endocrinol Metab (2004) 3.59
Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol (2004) 3.22
The ADVANCE study: a randomized study to evaluate the effects of cinacalcet plus low-dose vitamin D on vascular calcification in patients on hemodialysis. Nephrol Dial Transplant (2010) 3.10
Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men. J Clin Endocrinol Metab (2006) 3.08
Medial localization of mineralization-regulating proteins in association with Mönckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification. Circulation (1999) 2.95
Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free Radic Biol Med (2001) 2.79
Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro. Kidney Int (2010) 2.61
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. J Biol Chem (2008) 2.55
Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice. Circulation (2008) 2.44
Inorganic pyrophosphate generation and disposition in pathophysiology. Am J Physiol Cell Physiol (2001) 2.36
Annual progression of coronary calcification in trials of preventive therapies: a systematic review. Arch Intern Med (2009) 2.30
Structural basis of calcification inhibition by alpha 2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles. J Biol Chem (2003) 2.26
Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro. Kidney Int (2004) 2.25
Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells. Cardiovasc Res (2008) 2.23
RANKL increases vascular smooth muscle cell calcification through a RANK-BMP4-dependent pathway. Circ Res (2009) 2.17
Vascular calcification in chronic kidney disease. Am J Kidney Dis (2004) 1.81
Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification. J Am Soc Nephrol (2005) 1.70
Reduced plasma pyrophosphate levels in hemodialysis patients. J Am Soc Nephrol (2005) 1.68
Longitudinal relationships among coronary artery calcification, serum phosphorus, and kidney function. Clin J Am Soc Nephrol (2009) 1.62
PTH differentially regulates expression of RANKL and OPG. J Bone Miner Res (2003) 1.61
Vascular calcification is dependent on plasma levels of pyrophosphate. Kidney Int (2014) 1.57
Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels. Kidney Int (2003) 1.52
Revised microcalcification hypothesis for fibrous cap rupture in human coronary arteries. Proc Natl Acad Sci U S A (2013) 1.51
Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification. Circ Res (2012) 1.45
Angiotensin II accelerates osteoporosis by activating osteoclasts. FASEB J (2008) 1.42
Bisphosphonates alendronate and ibandronate inhibit artery calcification at doses comparable to those that inhibit bone resorption. Arterioscler Thromb Vasc Biol (2001) 1.38
On the prevention of secondary hyperparathyroidism in experimental chronic renal disease using "proportional reduction" of dietary phosphorus intake. Kidney Int (1972) 1.34
Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arterioscler Thromb Vasc Biol (2011) 1.34
Chemical and hormonal determinants of vascular calcification in vitro. Kidney Int (2006) 1.33
Biology of the TRANCE axis. Cytokine Growth Factor Rev (2003) 1.29
Has our understanding of calcification in human coronary atherosclerosis progressed? Arterioscler Thromb Vasc Biol (2014) 1.27
Renal osteodystrophy, phosphate homeostasis, and vascular calcification. Semin Dial (2007) 1.24
Inhibition of receptor activator of NF-kappaB ligand by denosumab attenuates vascular calcium deposition in mice. Am J Pathol (2009) 1.23
Vascular calcification and renal osteodystrophy relationship in chronic kidney disease. Eur J Clin Invest (2006) 1.22
Pathophysiology and recent advances in the management of renal osteodystrophy. J Bone Miner Res (2002) 1.21
Evidence for abnormal calcium homeostasis in patients with adynamic bone disease. Kidney Int (1994) 1.19
Conjoint effects of serum calcium and phosphate on risk of total, cardiovascular, and noncardiovascular mortality in the community. Arterioscler Thromb Vasc Biol (2009) 1.18
The mechanisms of uremic serum-induced expression of bone matrix proteins in bovine vascular smooth muscle cells. Kidney Int (2006) 1.18
Estrogen inhibits vascular calcification via vascular RANKL system: common mechanism of osteoporosis and vascular calcification. Circ Res (2010) 1.17
Sevelamer prevents uremia-enhanced atherosclerosis progression in apolipoprotein E-deficient mice. Circulation (2005) 1.14
Vascular calcifications, vertebral fractures and mortality in haemodialysis patients. Nephrol Dial Transplant (2008) 1.14
Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney disease. Am J Pathol (2011) 1.14
Bisphosphonate Use and Prevalence of Valvular and Vascular Calcification in Women MESA (The Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol (2010) 1.12
Role of osteoprotegerin in arterial calcification: development of new animal model. Arterioscler Thromb Vasc Biol (2007) 1.09
Sodium-dependent phosphate cotransporters and vascular calcification. Curr Opin Nephrol Hypertens (2007) 1.07
High phosphorus diet induces vascular calcification, a related decrease in bone mass and changes in the aortic gene expression. Bone (2009) 1.04
The calcimimetic R-568 retards uremia-enhanced vascular calcification and atherosclerosis in apolipoprotein E deficient (apoE-/-) mice. Atherosclerosis (2008) 0.99
Decrease in thoracic vertebral bone attenuation with calcium-based phosphate binders in hemodialysis. J Bone Miner Res (2004) 0.98
RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: dependence on IL-6 and TNF-α. J Vasc Res (2012) 0.96
The antioxidant tempol ameliorates arterial medial calcification in uremic rats: important role of oxidative stress in the pathogenesis of vascular calcification in chronic kidney disease. J Bone Miner Res (2012) 0.94
Cross-talk of receptor activator of nuclear factor-κB ligand signaling with renin-angiotensin system in vascular calcification. Arterioscler Thromb Vasc Biol (2013) 0.94
Effects of calcium on cardiovascular events in patients with kidney disease and in a healthy population. Clin J Am Soc Nephrol (2010) 0.94
Calcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: mechanisms of action. Cardiovasc Res (2013) 0.93
Oxidized low density lipoprotein inhibits phosphate signaling and phosphate-induced mineralization in osteoblasts. Involvement of oxidative stress. Biochim Biophys Acta (2010) 0.91
Effect of alendronate on vascular calcification in CKD stages 3 and 4: a pilot randomized controlled trial. Am J Kidney Dis (2010) 0.91
The calcimimetic AMG 641 abrogates parathyroid hyperplasia, bone and vascular calcification abnormalities in uremic rats. Eur J Pharmacol (2009) 0.90
Nuclear factor of activated T cells mediates oxidised LDL-induced calcification of vascular smooth muscle cells. Diabetologia (2011) 0.90
Expression of matrix Gla protein (MGP) in an in vitro model of vascular calcification. FEBS Lett (1998) 0.90
Inhibition of FOXO1/3 promotes vascular calcification. Arterioscler Thromb Vasc Biol (2014) 0.90
Function and effect of bone morphogenetic protein-7 in kidney bone and the bone-vascular links in chronic kidney disease. Eur J Clin Invest (2006) 0.89
Lanthanum carbonate delays progression of coronary artery calcification compared with calcium-based phosphate binders in patients on hemodialysis: a pilot study. J Cardiovasc Pharmacol Ther (2013) 0.89
Inhibition of the progression of aortic calcification by etidronate treatment in hemodialysis patients: long-term effects. Ther Apher Dial (2006) 0.88
Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice. J Bone Miner Res (2014) 0.87
Serum osteoprotegerin, RANKL and fibroblast growth factor-23 in children with chronic kidney disease. Pediatr Nephrol (2011) 0.87
Mechanisms of vascular calcification in uremia. Semin Nephrol (2004) 0.87
RANKL inhibition with denosumab does not influence 3-year progression of aortic calcification or incidence of adverse cardiovascular events in postmenopausal women with osteoporosis and high cardiovascular risk. J Bone Miner Res (2014) 0.85
Effective doses of ibandronate do not influence the 3-year progression of aortic calcification in elderly osteoporotic women. Osteoporos Int (2004) 0.85
Impact of inflammation and oxidative stress on vascular calcifications in chronic kidney disease. Pediatr Nephrol (2004) 0.85
Long-term sevelamer treatment lowers serum fibroblast growth factor 23 accompanied with increasing serum Klotho levels in chronic haemodialysis patients. Nephrology (Carlton) (2014) 0.84
Evaluation of RANKL/OPG Serum Concentration Ratio as a New Biomarker for Coronary Artery Calcification: A Pilot Study. Thrombosis (2012) 0.84
Blockage of the renin-angiotensin system attenuates mortality but not vascular calcification in uremic rats: sevelamer carbonate prevents vascular calcification. Am J Nephrol (2009) 0.84
Cross-sectional association of serum phosphate with carotid intima-medial thickness in hemodialysis patients. Am J Kidney Dis (2005) 0.83
Bisphosphonate therapy, death, and cardiovascular events among female patients with CKD: a retrospective cohort study. Am J Kidney Dis (2012) 0.82
Lanthanum carbonate, like sevelamer-HCl, retards the progression of vascular calcification and atherosclerosis in uremic apolipoprotein E-deficient mice. Nephrol Dial Transplant (2011) 0.81
Human uraemic serum displays calcific potential in vitro that increases with advancing chronic kidney disease. Clin Sci (Lond) (2013) 0.81
Effect of phosphate on parathyroid hormone secretion in vivo. J Bone Miner Res (1999) 0.81
Lanthanum prevents high phosphate-induced vascular calcification by preserving vascular smooth muscle lineage markers. Calcif Tissue Int (2013) 0.79
Long-term effect of cinacalcet hydrochloride on abdominal aortic calcification in patients on hemodialysis with secondary hyperparathyroidism. Int J Nephrol Renovasc Dis (2013) 0.79
The combination of lanthanum chloride and the calcimimetic calindol delays the progression of vascular smooth muscle cells calcification. Biochem Biophys Res Commun (2012) 0.79
Biochemical markers of vascular calcification in elderly hemodialysis patients. Mol Cell Biochem (2012) 0.79
Osteoprotegerin and kidney disease. J Nephrol (2014) 0.78
Protection against osteoporosis by statins is linked to a reduction of oxidative stress and restoration of nitric oxide formation in aged and ovariectomized rats. Eur J Pharmacol (2011) 0.78
High phosphate feeding promotes mineral and bone abnormalities in mice with chronic kidney disease. Nephrol Dial Transplant (2012) 0.77
Effects of alendronate on the Notch1‑RBP‑Jκ signaling pathway in the osteogenic differentiation and mineralization of vascular smooth muscle cells. Mol Med Rep (2013) 0.77
Involvement of parathyroid hormone-related protein in vascular calcification of chronic haemodialysis patients. Nephrology (Carlton) (2012) 0.76
Association between global biomarkers of oxidative stress and hip fracture in postmenopausal women: a prospective study. J Bone Miner Res (2014) 0.76
Clinical efficacy of sevelamer hydrochloride in patients with end-stage renal disease: a retrospective study. Singapore Med J (2013) 0.76
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. J Biol Chem (2008) 2.55
Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification. Circ Res (2012) 1.45
Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arterioscler Thromb Vasc Biol (2011) 1.34
Mechanisms and consequences of salt sensitivity and dietary salt intake. Curr Opin Nephrol Hypertens (2011) 1.09
A conserved domain of previously unknown function in Gap1 mediates protein-protein interaction and is required for biogenesis of a serine-rich streptococcal adhesin. Mol Microbiol (2008) 1.03
The effect of plasminogen activator inhibitor type 1 on apoptosis. Thromb Haemost (2008) 0.99
Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-extracellular signal-regulated kinase (ERK). J Biol Chem (2011) 0.96
Activation of AKT by O-linked N-acetylglucosamine induces vascular calcification in diabetes mellitus. Circ Res (2014) 0.95
Serum response factor regulates bone formation via IGF-1 and Runx2 signals. J Bone Miner Res (2012) 0.95
PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy. Clin Cancer Res (2013) 0.93
Conformation and free energy analyses of the complex of calcium-bound calmodulin and the Fas death domain. Biophys J (2008) 0.93
Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling. Biochem J (2008) 0.91
Molecular mechanisms of tamoxifen therapy for cholangiocarcinoma: role of calmodulin. Clin Cancer Res (2009) 0.90
Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma. Int J Oncol (2006) 0.88
RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis. J Biol Chem (2010) 0.87
Vascular smooth muscle cell Smad4 gene is important for mouse vascular development. Arterioscler Thromb Vasc Biol (2012) 0.85
Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma. Int J Oncol (2007) 0.85
Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis. Lab Invest (2011) 0.82
Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4. Lab Invest (2009) 0.81
Reduced CaM/FLIP binding by a single point mutation in c-FLIP(L) modulates Fas-mediated apoptosis and decreases tumorigenesis. Lab Invest (2011) 0.81
Structural and biophysical characterization of the interactions between the death domain of Fas receptor and calmodulin. J Biol Chem (2013) 0.80
Trifluoperazine regulation of calmodulin binding to Fas: a computational study. Proteins (2011) 0.78