Misdiagnosis of Myocardial Infarction Related to Limitations of the Current Regulatory Approach to Define Clinical Decision Values for Cardiac Troponin.

PubWeight™: 1.20‹?› | Rank: Top 10%

🔗 View Article (PMC 4456170)

Published in Circulation on May 06, 2015

Authors

Karin Wildi1, Maria Rubini Gimenez1, Raphael Twerenbold1, Tobias Reichlin1, Cedric Jaeger1, Amely Heinzelmann1, Christiane Arnold1, Berit Nelles1, Sophie Druey1, Philip Haaf1, Petra Hillinger1, Nicolas Schaerli1, Philipp Kreutzinger1, Yunus Tanglay1, Thomas Herrmann1, Zoraida Moreno Weidmann1, Lian Krivoshei1, Michael Freese1, Claudia Stelzig1, Christian Puelacher1, Katharina Rentsch1, Stefan Osswald1, Christian Mueller2

Author Affiliations

1: From Department of Cardiology and Cardiovascular Research Institute Basel (K.W., M.R.G., R.T., T.R., C.J., A.H., S.D., P.H., P.H., N.S., P.K., Y.T., T.H., Z.M.W., L.K., M.F., C.S., C.P., S.O., C.M.) and Laboratory Medicine (K.R.), University Hospital Basel, Switzerland; Servicio de Urgencias y Pneumologia, CIBERES ISC III, Hospital del Mar-Institut Municipal d'Investigació Mèdica, Barcelona, Spain (M.R.G.); and Department of Internal Medicine, Kantonsspital Olten, Switzerland (C.A.).
2: From Department of Cardiology and Cardiovascular Research Institute Basel (K.W., M.R.G., R.T., T.R., C.J., A.H., S.D., P.H., P.H., N.S., P.K., Y.T., T.H., Z.M.W., L.K., M.F., C.S., C.P., S.O., C.M.) and Laboratory Medicine (K.R.), University Hospital Basel, Switzerland; Servicio de Urgencias y Pneumologia, CIBERES ISC III, Hospital del Mar-Institut Municipal d'Investigació Mèdica, Barcelona, Spain (M.R.G.); and Department of Internal Medicine, Kantonsspital Olten, Switzerland (C.A.). Christian.Mueller@usb.ch.

Associated clinical trials:

Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study (APACE) | NCT00470587

Articles cited by this

Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med (2006) 32.81

ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J (2011) 13.10

Universal definition of myocardial infarction. Circulation (2007) 11.69

Third universal definition of myocardial infarction. Circulation (2012) 8.47

Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. N Engl J Med (2009) 8.05

Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med (2009) 6.62

National Hospital Ambulatory Medical Care Survey: 2005 emergency department summary. Adv Data (2007) 4.51

One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T. Arch Intern Med (2012) 4.24

Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction. Circulation (2011) 3.72

Analytical validation of a high-sensitivity cardiac troponin T assay. Clin Chem (2009) 3.24

Analytical characteristics of high-sensitivity cardiac troponin assays. Clin Chem (2011) 2.51

Validation of high-sensitivity troponin I in a 2-hour diagnostic strategy to assess 30-day outcomes in emergency department patients with possible acute coronary syndrome. J Am Coll Cardiol (2013) 2.28

Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population. Clin Chem (2012) 2.19

Introduction of high-sensitivity troponin assays: impact on myocardial infarction incidence and prognosis. Am J Med (2012) 2.14

European Society of Cardiology and American College of Cardiology guidelines for redefinition of myocardial infarction: how to use existing assays clinically and for clinical trials. Am Heart J (2002) 2.11

Short- and long-term biological variation in cardiac troponin I measured with a high-sensitivity assay: implications for clinical practice. Clin Chem (2008) 2.11

How to use high-sensitivity cardiac troponins in acute cardiac care. Eur Heart J (2012) 2.00

Analytic and clinical utility of a next-generation, highly sensitive cardiac troponin I assay for early detection of myocardial injury. Clin Chem (2009) 1.82

2012 ACCF/AHA focused update incorporated into the ACCF/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation (2013) 1.81

Prevalence and factors associated with false-positive ST-segment elevation myocardial infarction diagnoses at primary percutaneous coronary intervention–capable centers: a report from the Activate-SF registry. Arch Intern Med (2012) 1.79

National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: Analytical issues for biochemical markers of acute coronary syndromes. Circulation (2007) 1.62

Biological and analytical variability of a novel high-sensitivity cardiac troponin T assay. Clin Chem (2010) 1.52

Multicenter analytical evaluation of a high-sensitivity troponin T assay. Clin Chim Acta (2011) 1.49

Direct comparison of high-sensitivity-cardiac troponin I vs. T for the early diagnosis of acute myocardial infarction. Eur Heart J (2014) 1.35

Early diagnosis of acute myocardial infarction in the elderly using more sensitive cardiac troponin assays. Eur Heart J (2011) 1.31

Influence of population selection on the 99th percentile reference value for cardiac troponin assays. Clin Chem (2011) 1.28

Role of monitoring changes in sensitive cardiac troponin I assay results for early diagnosis of myocardial infarction and prediction of risk of adverse events. Clin Chem (2009) 1.25

An epidemiologic study of closed emergency department malpractice claims in a national database of physician malpractice insurers. Acad Emerg Med (2010) 1.23

Evaluation of high-sensitivity assays for cardiac troponin. Clin Chem (2008) 1.22

Defining high-sensitivity cardiac troponin concentrations in the community. Clin Chem (2013) 0.95

Effect of population selection on 99th percentile values for a high sensitivity cardiac troponin I and T assays. Clin Biochem (2013) 0.90

Defining a reference population to determine the 99th percentile of a contemporary sensitive cardiac troponin I assay. Int J Cardiol (2012) 0.90

Characterisation of a highly sensitive troponin I assay and its application to a cardio-healthy population. Clin Chem Lab Med (2012) 0.85