Expression of GITR Enhances Multiple Myeloma Cell Sensitivity to Bortezomib.

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med (2005) 15.30

Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells. Blood (2009) 3.12

Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides. Blood (2012) 2.98

Molecular alterations in primary prostate cancer after androgen ablation therapy. Clin Cancer Res (2005) 1.88

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3. Proc Natl Acad Sci U S A (1995) 1.82

Constitutional 1p36 deletion in a child with neuroblastoma. Am J Hum Genet (1993) 1.75

Dual inhibition of canonical and noncanonical NF-κB pathways demonstrates significant antitumor activities in multiple myeloma. Clin Cancer Res (2012) 1.73

Bortezomib-resistant nuclear factor-kappaB activity in multiple myeloma cells. Mol Cancer Res (2008) 1.52

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs. Cell Death Differ (2010) 1.20

Blocking autophagy prevents bortezomib-induced NF-κB activation by reducing I-κBα degradation in lymphoma cells. PLoS One (2012) 1.16

Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers. Genes Chromosomes Cancer (2000) 1.15

A co-evolution perspective of the TNFSF and TNFRSF families in the immune system. Trends Immunol (2003) 1.12

Defining the role of TORC1/2 in multiple myeloma. Blood (2011) 1.10

A distinctive subtype of t(14;18)-negative nodal follicular non-Hodgkin lymphoma characterized by a predominantly diffuse growth pattern and deletions in the chromosomal region 1p36. Blood (2008) 1.08

CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling. Blood (2002) 1.03

Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells. PLoS One (2013) 0.99

Frameshift mutations of RIZ, but no point mutations in RIZ1 exons in malignant melanomas with deletions in 1p36. Oncogene (2002) 0.94

Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation. Cell Death Dis (2013) 0.92

Bortezomib: understanding the mechanism of action. Mol Cancer Ther (2011) 0.92

Regulation of NF-kB in multiple myeloma: therapeutic implications. Clin Adv Hematol Oncol (2004) 0.89

T cell costimulation by TNFR superfamily (TNFRSF)4 and TNFRSF25 in the context of vaccination. J Immunol (2012) 0.84

Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma. PLoS One (2013) 0.82

Bortezomib inhibits C2C12 growth by inducing cell cycle arrest and apoptosis. Biochem Biophys Res Commun (2014) 0.80

Sevoflurane prevents stroke-induced depressive and anxiety behaviors by promoting cannabinoid receptor subtype I-dependent interaction between β-arrestin 2 and extracellular signal-regulated kinases 1/2 in the rat hippocampus. J Neurochem (2016) 0.78