Published in Philos Trans R Soc Lond B Biol Sci on July 05, 2015
The Multifaceted Role of SNARE Proteins in Membrane Fusion. Front Physiol (2017) 0.77
Release of chemical transmitters from cell bodies and dendrites of nerve cells. Philos Trans R Soc Lond B Biol Sci (2015) 0.76
Three-dimensional imaging of Drosophila motor synapses reveals ultrastructural organizational patterns. J Neurogenet (2016) 0.76
SNAREpins: minimal machinery for membrane fusion. Cell (1998) 16.97
Molecular anatomy of a trafficking organelle. Cell (2006) 11.47
Membrane fusion: grappling with SNARE and SM proteins. Science (2009) 8.98
Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release. J Cell Biol (1979) 8.78
Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse. Cell (1994) 7.43
Synapses in the central nervous system. J Biophys Biochem Cytol (1956) 6.63
Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science (1992) 5.00
Mechanics of membrane fusion. Nat Struct Mol Biol (2008) 4.79
Optical analysis of synaptic vesicle recycling at the frog neuromuscular junction. Science (1992) 4.56
Multiple roles of calcium ions in the regulation of neurotransmitter release. Neuron (2008) 4.23
Synaptic vesicle fusion. Nat Struct Mol Biol (2008) 4.22
Functional changes in frog neuromuscular junctions studied with freeze-fracture. J Neurocytol (1974) 4.04
Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis. Science (2004) 3.81
VAMP-1: a synaptic vesicle-associated integral membrane protein. Proc Natl Acad Sci U S A (1988) 3.76
Molecular machines governing exocytosis of synaptic vesicles. Nature (2012) 3.66
Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release. Neuron (1993) 3.07
Neurotransmitter release: the last millisecond in the life of a synaptic vesicle. Neuron (2013) 2.94
[Synaptic vesicles and pouches at the level of "active zones" of the neuromuscular junction]. C R Acad Sci Hebd Seances Acad Sci D (1970) 2.72
The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo. Nature (2002) 2.60
Endocytosis of synaptic vesicle membrane at the frog neuromuscular junction. J Cell Biol (1984) 2.50
The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1. J Cell Biol (1989) 2.47
Structural changes after transmitter release at the frog neuromuscular junction. J Cell Biol (1981) 2.37
The architecture of active zone material at the frog's neuromuscular junction. Nature (2001) 2.26
Are the presynaptic membrane particles the calcium channels? Proc Natl Acad Sci U S A (1981) 2.22
A synaptic vesicle membrane protein is conserved from mammals to Drosophila. Neuron (1989) 2.21
A synaptic vesicle protein with a novel cytoplasmic domain and four transmembrane regions. Science (1987) 2.21
Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex. Nat Struct Mol Biol (2011) 1.95
Estimates of quantal content during 'chemical potentiation' of transmitter release. Proc R Soc Lond B Biol Sci (1979) 1.92
Open syntaxin docks synaptic vesicles. PLoS Biol (2007) 1.90
The organization of cytoplasm at the presynaptic active zone of a central nervous system synapse. Neuron (1988) 1.87
Differential expression of synaptic vesicle protein 2 (SV2) isoforms. J Neurosci (1994) 1.84
The architecture of the active zone in the presynaptic nerve terminal. Physiology (Bethesda) (2004) 1.84
Intramembrane organization of specialized contacts in the outer plexiform layer of the retina. A freeze-fracture study in monkeys and rabbits. J Cell Biol (1975) 1.84
Three-dimensional architecture of presynaptic terminal cytomatrix. J Neurosci (2007) 1.82
On understanding the organisation of the retinal receptor synapses. Brain Res (1971) 1.58
The fusion pores of Ca2+ -triggered exocytosis. Nat Struct Mol Biol (2008) 1.57
Analysis of synaptic ultrastructure without fixative using high-pressure freezing and tomography. Eur J Neurosci (2006) 1.54
Electron microscopy of presynaptic organelles of the spinal cord. J Anat (1963) 1.50
Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography. J Cell Biol (2010) 1.48
Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans. J Biol Chem (1991) 1.47
Unraveling the mechanism of the vesicle transport ATPase NSF, the N-ethylmaleimide-sensitive factor. J Biol Chem (2001) 1.24
Mechanical unzipping and rezipping of a single SNARE complex reveals hysteresis as a force-generating mechanism. Nat Commun (2013) 1.15
Cryomethods for thin section electron microscopy. Methods Enzymol (2002) 1.14
The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Neuron (2014) 1.11
The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactions. J Neurosci (2011) 1.11
Mechanistic basis for low threshold mechanosensitivity in voltage-dependent K+ channels. Proc Natl Acad Sci U S A (2012) 1.09
Priming in exocytosis: attaining fusion-competence after vesicle docking. Biochimie (2000) 1.08
Macromolecular connections of active zone material to docked synaptic vesicles and presynaptic membrane at neuromuscular junctions of mouse. J Comp Neurol (2009) 1.07
Consequences of molecular-level Ca2+ channel and synaptic vesicle colocalization for the Ca2+ microdomain and neurotransmitter exocytosis: a monte carlo study. Biophys J (2004) 1.06
Quantitative localization of Cav2.1 (P/Q-type) voltage-dependent calcium channels in Purkinje cells: somatodendritic gradient and distinct somatic coclustering with calcium-activated potassium channels. J Neurosci (2013) 1.05
Cryo-electron tomography reveals a critical role of RIM1α in synaptic vesicle tethering. J Cell Biol (2013) 1.05
Ca2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivo. J Neurosci (2008) 1.01
Contribution of active zone subpopulation of vesicles to evoked and spontaneous release. J Neurophysiol (1999) 1.00
Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission. J Neurosci (2012) 0.99
Ultrastructural organization of lamprey reticulospinal synapses in three dimensions. J Comp Neurol (2002) 0.99
Automatic acquisition of fiducial markers and alignment of images in tilt series for electron tomography. J Electron Microsc (Tokyo) (1999) 0.99
Conical electron tomography of a chemical synapse: polyhedral cages dock vesicles to the active zone. J Neurosci (2008) 0.98
Regulation of synaptic vesicle docking by different classes of macromolecules in active zone material. PLoS One (2012) 0.96
Comment on "Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis". Science (2004) 0.96
Two pools of vesicles associated with the presynaptic cytosolic projection in Drosophila neuromuscular junctions. J Struct Biol (2010) 0.94
Methods for generating high-resolution structural models from electron microscope tomography data. Structure (2004) 0.94
Evolutionary progression at synaptic connections made by identified homologous neurones. Proc Natl Acad Sci U S A (1986) 0.93
Ultrastructural organization of presynaptic terminals. Curr Opin Neurobiol (2011) 0.92
Structural changes during transmitter release at synapses in the frog sympathetic ganglion. J Neurosci (1983) 0.90
Alignment of synaptic vesicle macromolecules with the macromolecules in active zone material that direct vesicle docking. PLoS One (2013) 0.89
A new kinetic framework for synaptic vesicle trafficking tested in synapsin knock-outs. J Neurosci (2011) 0.89
Role of PI(4,5)P(2) in vesicle exocytosis and membrane fusion. Subcell Biochem (2012) 0.87
Synaptic vesicle capture by CaV2.2 calcium channels. Front Cell Neurosci (2013) 0.86