Coronary microvascular dysfunction: sex-specific risk, diagnosis, and therapy.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 26011377)

Published in Nat Rev Cardiol on May 26, 2015

Authors

Jenna Dean1, Sherwin Dela Cruz1, Puja K Mehta1, C Noel Bairey Merz1

Author Affiliations

1: Barbra Streisand Women's Heart Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, A3600, Los Angeles, CA 90048, USA.

Articles cited by this

(truncated to the top 100)

2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation (2013) 16.52

2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J (2013) 9.54

Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med (2000) 9.05

ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction): developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. Circulation (2007) 6.78

Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women. N Engl J Med (2006) 6.14

Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation (2000) 6.13

Endothelial dysfunction: a marker of atherosclerotic risk. Arterioscler Thromb Vasc Biol (2003) 6.04

Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation (2000) 5.53

Abnormal subendocardial perfusion in cardiac syndrome X detected by cardiovascular magnetic resonance imaging. N Engl J Med (2002) 5.42

Cigarette smoking as a risk factor for coronary heart disease in women compared with men: a systematic review and meta-analysis of prospective cohort studies. Lancet (2011) 5.33

Effectiveness-based guidelines for the prevention of cardiovascular disease in women--2011 update: a guideline from the american heart association. Circulation (2011) 5.26

Coronary microvascular dysfunction. N Engl J Med (2007) 5.22

Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. JAMA (2004) 4.80

TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation (1996) 4.41

Risk factors for myocardial infarction in women and men: insights from the INTERHEART study. Eur Heart J (2008) 3.64

The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up. Arch Intern Med (2004) 3.34

Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease. N Engl J Med (1995) 3.32

Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular coronary disease. J Am Coll Cardiol (2006) 3.25

Angina with "normal" coronary arteries: a changing philosophy. JAMA (2005) 2.98

2007 chronic angina focused update of the ACC/AHA 2002 guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 guidelines for the management of patients with chronic stable angina. J Am Coll Cardiol (2007) 2.95

Coronary microvascular reactivity to adenosine predicts adverse outcome in women evaluated for suspected ischemia results from the National Heart, Lung and Blood Institute WISE (Women's Ischemia Syndrome Evaluation) study. J Am Coll Cardiol (2010) 2.68

Persistent chest pain predicts cardiovascular events in women without obstructive coronary artery disease: results from the NIH-NHLBI-sponsored Women's Ischaemia Syndrome Evaluation (WISE) study. Eur Heart J (2006) 2.67

Effects of sex on coronary microvascular dysfunction and cardiac outcomes. Circulation (2014) 2.59

Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies. J Am Coll Cardiol (2006) 2.57

Impact of ethnicity and gender differences on angiographic coronary artery disease prevalence and in-hospital mortality in the American College of Cardiology-National Cardiovascular Data Registry. Circulation (2008) 2.53

Women and ischemic heart disease: evolving knowledge. J Am Coll Cardiol (2009) 2.49

Adverse cardiovascular outcomes in women with nonobstructive coronary artery disease: a report from the Women's Ischemia Syndrome Evaluation Study and the St James Women Take Heart Project. Arch Intern Med (2009) 2.48

Stable angina pectoris with no obstructive coronary artery disease is associated with increased risks of major adverse cardiovascular events. Eur Heart J (2011) 2.36

Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine. Heart (2006) 2.33

Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina. J Am Coll Cardiol (2004) 2.31

Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE). Circulation (2004) 2.30

Coronary microvascular dysfunction is highly prevalent in women with chest pain in the absence of coronary artery disease: results from the NHLBI WISE study. Am Heart J (2001) 2.22

Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients. JACC Cardiovasc Imaging (2012) 2.17

Incidence and prognostic implications of stable angina pectoris among women and men. JAMA (2006) 2.16

Mechanisms of angina pectoris in syndrome X. J Am Coll Cardiol (1991) 2.16

Enhanced external counterpulsation is an effective treatment for Syndrome X. Int J Cardiol (2008) 2.15

Prognosis in women with myocardial ischemia in the absence of obstructive coronary disease: results from the National Institutes of Health-National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE). Circulation (2004) 2.12

The economic burden of angina in women with suspected ischemic heart disease: results from the National Institutes of Health--National Heart, Lung, and Blood Institute--sponsored Women's Ischemia Syndrome Evaluation. Circulation (2006) 2.03

Primary coronary microvascular dysfunction: clinical presentation, pathophysiology, and management. Circulation (2010) 2.03

Comparison of 15-year survival for men and women after initial medical or surgical treatment for coronary artery disease: a CASS registry study. Coronary Artery Surgery Study. J Am Coll Cardiol (1995) 1.86

Effects of ranolazine on exercise tolerance and HbA1c in patients with chronic angina and diabetes. Eur Heart J (2005) 1.79

Myocardial ischemia in the absence of obstructive coronary artery disease in systemic lupus erythematosus. JACC Cardiovasc Imaging (2011) 1.75

Global coronary flow reserve is associated with adverse cardiovascular events independently of luminal angiographic severity and modifies the effect of early revascularization. Circulation (2014) 1.68

Relation of baseline high-sensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER). Am J Cardiol (2010) 1.67

2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation (2014) 1.64

Role of chronic hyperglycemia in the pathogenesis of coronary microvascular dysfunction in diabetes. J Am Coll Cardiol (2003) 1.61

Coronary vascular dysfunction and prognosis in patients with chronic kidney disease. JACC Cardiovasc Imaging (2012) 1.61

Ivabradine improves coronary flow reserve in patients with stable coronary artery disease. Atherosclerosis (2010) 1.53

Relationships between coronary flow vasodilator capacity and small artery remodelling in hypertensive patients. J Hypertens (2003) 1.49

Coronary microvascular spasm triggers transient ischemic left ventricular diastolic abnormalities in patients with chest pain and angiographically normal coronary arteries. Atherosclerosis (2014) 1.48

Improved exercise capacity with acute aminophylline administration in patients with syndrome X. J Am Coll Cardiol (1989) 1.46

Some thoughts on the vasculopathy of women with ischemic heart disease. J Am Coll Cardiol (2006) 1.45

Esterified estrogens combined with methyltestosterone improve emotional well-being in postmenopausal women with chest pain and normal coronary angiograms. Menopause (2001) 1.45

Anatomic versus physiologic assessment of coronary artery disease. Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making. J Am Coll Cardiol (2013) 1.44

Meta-analysis of trials comparing beta-blockers, calcium antagonists, and nitrates for stable angina. JAMA (1999) 1.43

Does the beta-blocker nebivolol increase coronary flow reserve? Cardiovasc Drugs Ther (2007) 1.43

Efficacy and safety of fasudil in patients with stable angina: a double-blind, placebo-controlled, phase 2 trial. J Am Coll Cardiol (2005) 1.42

Angina with "normal" coronary arteries: sex differences in outcomes. Am Heart J (2007) 1.41

Are we using cardiovascular medications and coronary angiography appropriately in men and women with chest pain? Eur Heart J (2011) 1.36

Transthoracic Doppler echocardiography - noninvasive diagnostic window for coronary flow reserve assessment. Cardiovasc Ultrasound (2003) 1.34

Chest pain in women: clinical, investigative, and prognostic features. BMJ (1994) 1.32

Safety of coronary reactivity testing in women with no obstructive coronary artery disease: results from the NHLBI-sponsored WISE (Women's Ischemia Syndrome Evaluation) study. JACC Cardiovasc Interv (2012) 1.30

Coronary microvascular dysfunction: an update. Eur Heart J (2013) 1.28

Validation of a new noninvasive method (contrast-enhanced transthoracic second harmonic echo Doppler) for the evaluation of coronary flow reserve: comparison with intracoronary Doppler flow wire. J Am Coll Cardiol (1999) 1.28

C-reactive protein, clinical presentation, and ischemic activity in patients with chest pain and normal coronary angiograms. J Am Coll Cardiol (2003) 1.24

Long-term angiotensin-converting enzyme inhibition reduces plasma asymmetric dimethylarginine and improves endothelial nitric oxide bioavailability and coronary microvascular function in patients with syndrome X. Am J Cardiol (2002) 1.24

Ranolazine improves angina in women with evidence of myocardial ischemia but no obstructive coronary artery disease. JACC Cardiovasc Imaging (2011) 1.23

Estimation of coronary flow reserve using the Thrombolysis In Myocardial Infarction (TIMI) frame count method. Am J Cardiol (1999) 1.22

Prognostic value of global MR myocardial perfusion imaging in women with suspected myocardial ischemia and no obstructive coronary disease: results from the NHLBI-sponsored WISE (Women's Ischemia Syndrome Evaluation) study. JACC Cardiovasc Imaging (2010) 1.21

Nonobstructive coronary artery disease and risk of myocardial infarction. JAMA (2014) 1.17

Diabetic microvascular complications--can the presence of one predict the development of another? J Diabetes Complications (2006) 1.17

Atenolol versus amlodipine versus isosorbide-5-mononitrate on anginal symptoms in syndrome X. Am J Cardiol (1999) 1.15

An intravascular ultrasound analysis in women experiencing chest pain in the absence of obstructive coronary artery disease: a substudy from the National Heart, Lung and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE). J Interv Cardiol (2010) 1.14

Effect of chronic ANG I-converting enzyme inhibition on aging processes. II. Large arteries. Am J Physiol (1994) 1.12

Effects of statins on coronary and peripheral endothelial function in humans: a systematic review and meta-analysis of randomized controlled trials. Eur J Cardiovasc Prev Rehabil (2011) 1.12

Cardiac syndrome X and microvascular coronary dysfunction. Trends Cardiovasc Med (2012) 1.12

In women with symptoms of cardiac ischemia, nonobstructive coronary arteries, and microvascular dysfunction, angiotensin-converting enzyme inhibition is associated with improved microvascular function: A double-blind randomized study from the National Heart, Lung and Blood Institute Women's Ischemia Syndrome Evaluation (WISE). Am Heart J (2011) 1.10

Microvascular coronary dysfunction in women: pathophysiology, diagnosis, and management. Curr Probl Cardiol (2011) 1.08

Coronary microvascular dysfunction in the clinical setting: from mystery to reality. Eur Heart J (2012) 1.07

Safety assessment of raloxifene over eight years in a clinical trial setting. Curr Med Res Opin (2005) 1.05

Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: a meta-analysis of randomised controlled trials. Atherosclerosis (2011) 1.04

Effects of ivabradine and ranolazine in patients with microvascular angina pectoris. Am J Cardiol (2013) 1.04

Assessment of flow velocity reserve by transthoracic Doppler echocardiography and venous adenosine infusion before and after left anterior descending coronary artery stenting. J Am Coll Cardiol (2001) 1.03

Sex differences in clinical outcomes in patients with stable angina and no obstructive coronary artery disease. Am Heart J (2013) 1.02

Comparison of coronary thermodilution and Doppler velocity for assessing coronary flow reserve. Circulation (2003) 1.01

Coronary microvascular reactivity is only partially predicted by atherosclerosis risk factors or coronary artery disease in women evaluated for suspected ischemia: results from the NHLBI Women's Ischemia Syndrome Evaluation (WISE). Clin Cardiol (2007) 0.99

Value of intracoronary ultrasound and Doppler in the differentiation of angiographically normal coronary arteries: a prospective study in patients with angina pectoris. Eur Heart J (1996) 0.99

Efficacy of calcium channel blocker therapy for angina pectoris resulting from small-vessel coronary artery disease and abnormal vasodilator reserve. Am J Cardiol (1985) 0.98

Adverse outcomes among women presenting with signs and symptoms of ischemia and no obstructive coronary artery disease: findings from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) angiographic core laboratory. Am Heart J (2013) 0.97

Coronary microvascular dysfunction: mechanisms and functional assessment. Nat Rev Cardiol (2014) 0.97

Inflammation and microvascular dysfunction in cardiac syndrome X patients without conventional risk factors for coronary artery disease. JACC Cardiovasc Imaging (2013) 0.97

Cognitive-behavioral therapy for noncardiac chest pain: a randomized trial. Am J Med (1999) 0.96

Comparison of verapamil versus propranolol therapy in syndrome X. Am J Cardiol (1989) 0.96

Cardiac magnetic resonance imaging myocardial perfusion reserve index assessment in women with microvascular coronary dysfunction and reference controls. Cardiovasc Diagn Ther (2013) 0.96

17-beta-Estradiol therapy lessens angina in postmenopausal women with syndrome X. J Am Coll Cardiol (1996) 0.95

Ischemic heart disease in women. J Am Coll Cardiol (2006) 0.94

Assessment of systemic inflammation and infective pathogen burden in patients with cardiac syndrome X. Am J Cardiol (2004) 0.94

Effect of transcutaneous electrical nerve stimulation on coronary blood flow. Circulation (1994) 0.94

Gender differences in myocardial blood flow dynamics: lipid profile and hemodynamic effects. J Am Coll Cardiol (1999) 0.93

Angina 1 year after percutaneous coronary intervention: a report from the NHLBI Dynamic Registry. Am Heart J (2002) 0.93