Published in Gene Ther on June 18, 2015
Ubiquitin signaling in immune responses. Cell Res (2016) 0.80
Phorbol ester-mediated re-expression of endogenous LAT adapter in J.CaM2 cells: a model for dissecting drivers and blockers of LAT transcription. Genes Immun (2016) 0.75
Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function. PLoS One (2017) 0.75
T cell receptor antagonist peptides induce positive selection. Cell (1994) 18.66
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med (2007) 11.82
Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells. J Exp Med (2003) 11.08
Adoptive immunotherapy for cancer: building on success. Nat Rev Immunol (2006) 7.76
Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol (2012) 7.39
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells. J Clin Invest (2005) 7.01
Memory CD8 T-cell differentiation during viral infection. J Virol (2004) 6.75
LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell (1998) 6.15
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells. Proc Natl Acad Sci U S A (2005) 5.21
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity (2009) 4.85
Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii. J Immunol (1992) 4.02
Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins. Annu Rev Immunol (2001) 3.95
IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy. Blood (2008) 3.52
Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology. Immunity (2013) 2.69
Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity. Proc Natl Acad Sci U S A (2009) 2.56
Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase. Immunity (2009) 2.51
A20: linking a complex regulator of ubiquitylation to immunity and human disease. Nat Rev Immunol (2012) 2.47
A look at autoimmunity and inflammation in the eye. J Clin Invest (2010) 2.30
Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity. Proc Natl Acad Sci U S A (2008) 2.07
In vivo discovery of immunotherapy targets in the tumour microenvironment. Nature (2014) 2.05
Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy. Blood (2010) 2.01
Naive, effector, and memory CD8 T cells in protection against pulmonary influenza virus infection: homing properties rather than initial frequencies are crucial. J Immunol (1999) 1.99
SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. J Exp Med (2006) 1.92
The LAT story: a tale of cooperativity, coordination, and choreography. Cold Spring Harb Perspect Biol (2010) 1.77
Single-dose mucosal immunization with a candidate universal influenza vaccine provides rapid protection from virulent H5N1, H3N2 and H1N1 viruses. PLoS One (2010) 1.64
Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70. J Biol Chem (1995) 1.60
Sorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy? J Immunother (2012) 1.47
c-Cbl-mediated regulation of LAT-nucleated signaling complexes. Mol Cell Biol (2007) 1.46
Functional properties of interphotoreceptor retinoid-binding protein. Photochem Photobiol (1991) 1.44
Vaccination focusing immunity on conserved antigens protects mice and ferrets against virulent H1N1 and H5N1 influenza A viruses. Vaccine (2009) 1.42
Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment. Mol Ther (2011) 1.36
Experimental autoimmune encephalomyelitis in the mouse. Curr Protoc Immunol (2010) 1.33
Experimental autoimmune uveoretinitis in the rat and mouse. Curr Protoc Immunol (2003) 1.32
Targeted Sos1 deletion reveals its critical role in early T-cell development. Proc Natl Acad Sci U S A (2011) 1.30
Cross-protective immunity to influenza A viruses. Expert Rev Vaccines (2010) 1.28
Ubiquitin makes its mark on immune regulation. Immunity (2010) 1.25
Functional dissection of the murine lck distal promoter. J Immunol (1995) 1.22
Enhanced effector responses in activated CD8+ T cells deficient in diacylglycerol kinases. Cancer Res (2013) 1.16
Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells. J Exp Med (2014) 1.16
EAE: imperfect but useful models of multiple sclerosis. Trends Mol Med (2011) 1.16
Deconstructing Ras signaling in the thymus. Mol Cell Biol (2012) 1.09
Negative regulation of TCR signaling and T-cell activation by selective protein degradation. Curr Opin Immunol (2003) 1.03
Abrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice. J Clin Invest (2010) 1.02
Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation. Proc Natl Acad Sci U S A (2011) 0.99
Genetic control of immune responses to influenza A matrix 2 protein (M2). Vaccine (2010) 0.88
Enhanced function of redirected human T cells expressing linker for activation of T cells that is resistant to ubiquitylation. Hum Gene Ther (2012) 0.82