Naturally occurring reoviruses for human cancer therapy.

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Published in BMB Rep on August 01, 2015

Authors

Manbok Kim1

Author Affiliations

1: Department of Medical Science, Dankook University College of Medicine, Cheonan 31116, Korea.

Associated clinical trials:

Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers | NCT01166542

Viral Therapy in Treating Young Patients With Relapsed or Refractory Solid Tumors | NCT01240538

Carboplatin and Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Metastatic Pancreatic Cancer | NCT01280058

Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer | NCT01274624

Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin for Non-Small Cell Lung Cancer With KRAS or EGFR Activation | NCT00861627

A Study of REOLYSIN® in Combination With Gemcitabine in Patients With Advanced Pancreatic Adenocarcinoma | NCT00998322

A Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Squamous Cell Carcinoma of the Lung | NCT00998192

Reolysin in Patients With Previously Treated Advanced or Metastatic, Non Small Cell Lung Cancer Receiving Standard Salvage Therapy | NCT01708993

Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma | NCT00984464

Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer | NCT01199263

Viral Therapy in Treating Patients With Relapsed or Refractory Multiple Myeloma | NCT01533194

Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas | NCT00528684

Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Metastatic Colorectal Cancer | NCT01622543

Viral Therapy in Treating Patients With Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer That Did Not Respond to Platinum Chemotherapy | NCT00602277

Reolysin Combined With Docetaxel and Prednisone or Docetaxel and Prednisone Alone in Metastatic Castration Resistant Prostate Cancer | NCT01619813

Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Head and Neck Carcinoma | NCT00753038

Viral Therapy in Treating Patients With Metastatic Melanoma | NCT00651157

A Study of Reolysin For Patients With Advanced/Metastatic Breast Cancer | NCT01656538

Wild-type Reovirus in Combination With Carfilzomib and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma | NCT02101944

Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung | NCT00503295

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