Loss of heterozygosity at D8S262: an early genetic event of hepatocarcinogenesis.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4469120)

Published in Diagn Pathol on June 16, 2015

Authors

Qiao Zhu1, Li Gong2, Xiaoyan Liu1, Jun Wang1, Pin Ren1, Wendong Zhang3, Li Yao1, Xiujuan Han1, Shaojun Zhu1, Miao Lan1, Yanhong Li4,5, Wei Zhang6

Author Affiliations

1: The Helmholtz Sino-German Laboratory for Cancer Research, Department of Pathology, Tangdu Hospital, the Fourth Military Medical University, Xi'an, 710038, People's Republic of China.
2: The Helmholtz Sino-German Laboratory for Cancer Research, Department of Pathology, Tangdu Hospital, the Fourth Military Medical University, Xi'an, 710038, People's Republic of China. glzwd16@fmmu.edu.cn.
3: Department of Rehabilitation Medicine, Tangdu Hospital, the Fourth Military Medical University, Xi'an, 710038, People's Republic of China.
4: The Helmholtz Sino-German Laboratory for Cancer Research, Department of Pathology, Tangdu Hospital, the Fourth Military Medical University, Xi'an, 710038, People's Republic of China. lyhzhw@fmmu.edu.cn.
5: Department of Gynaecology and Obstetrics, Tangdu Hospital, the Fourth Military Medical University, Xi'an, 710038, People's Republic of China. lyhzhw@fmmu.edu.cn.
6: The Helmholtz Sino-German Laboratory for Cancer Research, Department of Pathology, Tangdu Hospital, the Fourth Military Medical University, Xi'an, 710038, People's Republic of China. zhwlyh@fmmu.edu.cn.

Articles cited by this

Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet (2002) 7.67

Focus on hepatocellular carcinoma. Cancer Cell (2004) 3.49

The presence of multiple regions of homozygous deletion at the CSMD1 locus in oral squamous cell carcinoma question the role of CSMD1 in head and neck carcinogenesis. Genes Chromosomes Cancer (2003) 2.24

Genetic mechanisms of hepatocarcinogenesis. Oncogene (2002) 2.21

Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma. Hepatology (2010) 1.97

Survival analysis of genome-wide gene expression profiles of prostate cancers identifies new prognostic targets of disease relapse. Cancer Res (2003) 1.81

Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors. Hum Mol Genet (2004) 1.80

Loss of CSMD1 expression is associated with high tumour grade and poor survival in invasive ductal breast carcinoma. Breast Cancer Res Treat (2009) 1.73

Hepatocellular carcinoma (HCC): a global perspective. J Clin Gastroenterol (2010) 1.49

Are there any more ovarian tumor suppressor genes? A new perspective using ultra high-resolution copy number and loss of heterozygosity analysis. Genes Chromosomes Cancer (2009) 1.31

Update on precursor and early lesions of hepatocellular carcinomas. Arch Pathol Lab Med (2011) 1.26

Somatic mutations to CSMD1 in colorectal adenocarcinomas. Cancer Biol Ther (2008) 1.15

Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis. Hepatology (2007) 1.15

Allelic imbalances and homozygous deletion on 8p23.2 for stepwise progression of hepatocarcinogenesis. Hepatology (2009) 1.15

Characterization CSMD1 in a large set of primary lung, head and neck, breast and skin cancer tissues. Cancer Biol Ther (2009) 1.14

Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis. J Pathol (2003) 1.11

Genome-wide copy number alterations detection in fresh frozen and matched FFPE samples using SNP 6.0 arrays. Genes Chromosomes Cancer (2008) 1.08

Preneoplastic significance of hepatic iron-free foci in genetic hemochromatosis: a study of 185 patients. Hepatology (1993) 1.03

Loss of heterozygosity of chromosome 8p and 11p in the dysplastic nodule and hepatocellular carcinoma. J Gastroenterol Hepatol (2003) 0.98

Relevance of hepatic preneoplasia for human hepatocarcinogenesis. Toxicol Pathol (2003) 0.96

Molecular changes in hepatocellular dysplastic nodules on microdissected liver biopsies. Hepatology (2000) 0.92

Clonality of nodular lesions in liver cirrhosis and chromosomal abnormalities in monoclonal nodules of altered hepatocytes. Histopathology (2010) 0.85

Frequent loss of heterozygosity in two distinct regions, 8p23.1 and 8p22, in hepatocellular carcinoma. World J Gastroenterol (2007) 0.85

Dysplastic nodules with glypican-3 positive immunostaining: a risk for early hepatocellular carcinoma. PLoS One (2014) 0.82

Histochemical and immunohistochemical detection of putative preneoplastic liver foci in women after long-term use of oral contraceptives. Virchows Arch B Cell Pathol Incl Mol Pathol (1986) 0.82

Identification of minimal regions of deletion at 8p23.1-22 associated with metastasis of hepatocellular carcinoma. Liver Int (2007) 0.81

Focal hepatic glycogenosis. Int J Oncol (1997) 0.81

Preneoplastic lesions of human liver. Hepatogastroenterology (1987) 0.78

Resistance to iron accumulation and presence of hepatitis B surface antigen in preneoplastic and neoplastic lesions in human hemochromatotic livers. Hepatogastroenterology (1982) 0.78