Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study.

PubWeight™: 0.76‹?›

🔗 View Article (PMID 26121922)

Published in Neurotoxicology on June 26, 2015

Authors

Rachel Grashow1, David Sparrow2, Howard Hu3, Marc G Weisskopf4

Author Affiliations

1: Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Civil and Environmental Engineering, Northeastern University, Boston, MA, USA. Electronic address: r.grashow@neu.edu.
2: VA Boston Healthcare System, Boston University Schools of Public Health and Medicine, Boston, MA, USA; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
3: Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
4: Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Articles citing this

Effects of Ambient Air Pollution Exposure on Olfaction: A Review. Environ Health Perspect (2016) 0.75

Articles cited by this

Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function. Physiol Behav (1984) 6.50

Elevated serum pesticide levels and risk for Alzheimer disease. JAMA Neurol (2014) 4.30

The relationship of bone and blood lead to hypertension. The Normative Aging Study. JAMA (1996) 3.87

Bone lead as a biological marker in epidemiologic studies of chronic toxicity: conceptual paradigms. Environ Health Perspect (1998) 3.51

Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology (2000) 3.01

The Veterans Administration longitudinal study of healthy aging. Gerontologist (1966) 2.22

Environmental lead exposure and cognitive function in community-dwelling older adults. Neurology (2006) 2.07

Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease. Neurotoxicology (1999) 1.95

Cumulative exposure to lead in relation to cognitive function in older women. Environ Health Perspect (2008) 1.87

Cumulative lead exposure and prospective change in cognition among elderly men: the VA Normative Aging Study. Am J Epidemiol (2004) 1.86

Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferro-manganese emission. Neurotoxicology (2012) 1.81

New and evolving concepts in the neurotoxicology of lead. Toxicol Appl Pharmacol (2007) 1.74

Neurotoxic effects and biomarkers of lead exposure: a review. Rev Environ Health (2009) 1.74

Internal consistency reliability of the fractionated and whole University of Pennsylvania Smell Identification Test. Percept Psychophys (1989) 1.63

HFE genotype, particulate air pollution, and heart rate variability: a gene-environment interaction. Circulation (2006) 1.59

Olfactory thresholds are associated with degree of dementia in Alzheimer's disease. Neurobiol Aging (1990) 1.58

Improvements in the calibration of 109Cd K x-ray fluorescence systems for measuring bone lead in vivo. Phys Med Biol (1994) 1.54

Relations of bone and blood lead to cognitive function: the VA Normative Aging Study. Neurotoxicol Teratol (1998) 1.50

Cumulative lead exposure and cognitive performance among elderly men. Epidemiology (2007) 1.46

Molecular bases of cellular iron toxicity. Free Radic Biol Med (2002) 1.44

Lead exposure biomarkers and mini-mental status exam scores in older men. Epidemiology (2003) 1.44

Olfaction in neurodegenerative disorder. Adv Otorhinolaryngol (2006) 1.35

Redox-active metals, oxidative stress, and Alzheimer's disease pathology. Ann N Y Acad Sci (2004) 1.28

Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort. Neurology (2013) 1.26

The presence of apoE4, not the absence of apoE3, contributes to AD pathology. J Alzheimers Dis (2002) 1.26

Urban air pollution: influences on olfactory function and pathology in exposed children and young adults. Exp Toxicol Pathol (2009) 1.23

Decrements in neurobehavioral performance associated with mixed exposure to organic and inorganic lead. Am J Epidemiol (1993) 1.20

Elevated serum pesticide levels and risk of Parkinson disease. Arch Neurol (2009) 1.19

Olfactory function distinguishes vascular parkinsonism from Parkinson's disease. J Neurol Neurosurg Psychiatry (2004) 1.16

Association between hemochromatosis genotype and lead exposure among elderly men: the normative aging study. Environ Health Perspect (2004) 1.15

Nasal toxicity, carcinogenicity, and olfactory uptake of metals. Ann Clin Lab Sci (2001) 1.13

Whole-body lifetime occupational lead exposure and risk of Parkinson's disease. Environ Health Perspect (2006) 1.12

Pre-motor features of Parkinson's disease: the Honolulu-Asia Aging Study experience. Parkinsonism Relat Disord (2012) 1.10

Association of cumulative lead exposure with Parkinson's disease. Environ Health Perspect (2010) 1.08

Comparison of neurobehavioral function in workers exposed to a mixture of organic and inorganic lead and in workers exposed to solvents. Am J Ind Med (1995) 1.07

Cumulative lead dose and cognitive function in older adults. Epidemiology (2009) 1.07

Longitudinal changes in bone lead levels: the VA Normative Aging Study. J Occup Environ Med (2011) 1.06

Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models. Environ Health (2011) 1.06

Olfactory dysfunction in Parkinson's disease. Neurosignals (2007) 1.04

Impaired olfaction predicts cognitive decline in nondemented older adults. Neuroepidemiology (2002) 1.02

HFE gene variants affect iron in the brain. J Nutr (2011) 1.00

Acetylcholinesterase activity in the brain of rat pups and dams after exposure to lead via the maternal water supply. Neurotoxicology (1984) 1.00

Association between inflammatory marker, environmental lead exposure, and glutathione S-transferase gene. Biomed Res Int (2013) 0.99

Olfactory deficit detected by fMRI in early Alzheimer's disease. Brain Res (2010) 0.95

Effects of hemochromatosis and transferrin gene mutations on peripheral iron dyshomeostasis in mild cognitive impairment and Alzheimer's and Parkinson's diseases. Front Aging Neurosci (2013) 0.95

Olfactory function in chemical workers exposed to acrylate and methacrylate vapors. Am J Public Health (1989) 0.94

Absorption of manganese and iron in a mouse model of hemochromatosis. PLoS One (2013) 0.94

San Francisco/Oakland Bay Bridge Welder Study: olfactory function. Neurology (2007) 0.94

Modifying effects of the HFE polymorphisms on the association between lead burden and cognitive decline. Environ Health Perspect (2007) 0.91

Mild Parkinsonian signs are associated with lower olfactory test scores in the community-dwelling elderly. Mov Disord (2008) 0.90

Severe dysosmia is specifically associated with Alzheimer-like memory deficits in nondemented elderly retirees. Neuroepidemiology (2002) 0.90

Odor identification impairment in carriers of ApoE-varepsilon4 is independent of clinical dementia. Neurobiol Aging (2008) 0.90

Influence of age and age-related diseases on olfactory function. Ann N Y Acad Sci (1989) 0.89

Redox metals in Alzheimer's disease. Ann N Y Acad Sci (2004) 0.88

Interactions of metals and Apolipoprotein E in Alzheimer's disease. Front Aging Neurosci (2014) 0.88

Human transferrin (Tf): a single mutation at codon 570 determines Tf C1 or Tf C2 variant. Hum Genet (1997) 0.88

Evaluation of acute sensory--motor effects and test sensitivity using termiticide workers exposed to chlorpyrifos. Neurotoxicol Teratol (2001) 0.88

Bone lead levels are associated with measures of memory impairment in older adults. Neurotoxicology (2009) 0.88

Olfactory impairment after chronic occupational cadmium exposure. J Occup Med (1992) 0.87

An agreed statement on calculating lead concentration and uncertainty in XRF in vivo bone lead analysis. Appl Radiat Isot (2003) 0.87

Olfaction in persons with Alzheimer's disease. Neuropsychol Rev (1998) 0.86

The aging brain, metals and oxygen free radicals. Cell Mol Biol (Noisy-le-grand) (2000) 0.86

Solvent-associated decrements in olfactory function in paint manufacturing workers. Am J Ind Med (1990) 0.86

Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease. Neurobiol Aging (2014) 0.84

Olfactory discrimination predicts cognitive decline among community-dwelling older adults. Transl Psychiatry (2012) 0.84

Cumulative lead exposure in community-dwelling adults and fine motor function: comparing standard and novel tasks in the VA normative aging study. Neurotoxicology (2013) 0.83

Influences of olfactory impairment on depression, cognitive performance, and quality of life in Korean elderly. Eur Arch Otorhinolaryngol (2009) 0.82

Both odor identification and ApoE-ε4 contribute to normative cognitive aging. Psychol Aging (2011) 0.82

Modification of the association between lead exposure and amyotrophic lateral sclerosis by iron and oxidative stress related gene polymorphisms. Amyotroph Lateral Scler Frontotemporal Degener (2014) 0.81

Modifying roles of glutathione S-transferase polymorphisms on the association between cumulative lead exposure and cognitive function. Neurotoxicology (2013) 0.80

Smell impairment in workers occupationally exposed to cadmium. Acta Otolaryngol (2000) 0.80

Effects of lead exposure on nitric oxide-associated gene expression in the olfactory bulb of mice. Biol Trace Elem Res (2010) 0.78

Lead exposure and (n-3) fatty acid deficiency during rat neonatal development affect subsequent spatial task performance and olfactory discrimination. J Nutr (2005) 0.78

The regional distribution of lead in normal rat brain. Neurotoxicology (1982) 0.78

Olfactory dysfunction and dementia in Parkinson's disease. J Parkinsons Dis (2014) 0.77

Age and apolipoprotein E ε4 effects on neural correlates of odor memory. Behav Neurosci (2013) 0.77

Lead exposure and fear-potentiated startle in the VA Normative Aging Study: a pilot study of a novel physiological approach to investigating neurotoxicant effects. Neurotoxicol Teratol (2013) 0.76

[Study of the olfactory function of a group of workers with significant lead exposure]. G Ital Med Lav Ergon (2008) 0.76

Concurrent changes in regional cholinergic parameters and nest odor preference in the early postnatal rat after lead exposure. Neurotoxicology (1992) 0.75