Tramadol and Tramadol+Caffeine Synergism in the Rat Formalin Test Are Mediated by Central Opioid and Serotonergic Mechanisms.

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Published in Biomed Res Int on June 04, 2015

Authors

Norma Carrillo-Munguía1, Ma Eva González-Trujano2, Miguel Huerta3, Xochitl Trujillo3, M Irene Díaz-Reval1

Author Affiliations

1: Laboratorio "Farmacología del Dolor" del Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Avenida 25 de Julio 965, 28045 Colima, COL, Mexico.
2: Laboratorio de Neurofarmacología de Productos Naturales de la Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calzada México-Xochimilco 101, 14370 México City, DF, Mexico.
3: Unidad de Investigación Dr. Enrico Stefani del Centro Universitario de Investigaciones Biomédicas, Universidad de Colima, Avenida 25 de Julio 965, 28045 Colima, COL, Mexico.

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