Apoptosis pathway signature for prediction of treatment response and clinical outcome in childhood high risk B-Precursor acute lymphoblastic leukemia.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4497450)

Published in Am J Cancer Res on April 15, 2015

Authors

Ya-Hsuan Chang1, Yung-Li Yang2, Chung-Ming Chen1, Hsuan-Yu Chen3

Author Affiliations

1: Institute of Biomedical Engineering, National Taiwan University No1, Sec. 1, Jen-Ai Rd, Taipei 100, Taiwan.
2: Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University 1 Jen-Ai Road, Section 1, Taipei, Taiwan ; Department of Laboratory Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University 1 Jen-Ai Road, Section 1, Taipei, Taiwan.
3: Institute of Statistical Science, Academia Sinica 128 Academia Road, Section 2, Nankang, Taipei, Taiwan.

Articles cited by this

Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A (2001) 132.88

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics (2003) 82.89

Index for rating diagnostic tests. Cancer (1950) 27.09

Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature (2005) 19.56

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell (2002) 11.83

Treatment of acute lymphoblastic leukemia. N Engl J Med (2006) 11.30

Molecular networks as sensors and drivers of common human diseases. Nature (2009) 6.14

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. Lancet Oncol (2009) 5.22

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. N Engl J Med (2004) 4.16

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome. Blood (2010) 4.00

A general modular framework for gene set enrichment analysis. BMC Bioinformatics (2009) 3.92

Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG). Blood (2006) 3.91

Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Blood (2009) 2.86

Molecular genetics of acute lymphoblastic leukemia. J Clin Oncol (2005) 2.74

Long-term results of the children's cancer group studies for childhood acute lymphoblastic leukemia 1983-2002: a Children's Oncology Group Report. Leukemia (2009) 2.58

Risk factors for acute leukemia in children: a review. Environ Health Perspect (2007) 2.57

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected]. J Clin Oncol (2008) 2.51

A set of genes that regulate cell proliferation predicts treatment outcome in childhood acute lymphoblastic leukemia. Blood (2007) 2.19

Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group study. Blood (2006) 1.74

Gene set-based analysis of polymorphisms: finding pathways or biological processes associated to traits in genome-wide association studies. Nucleic Acids Res (2009) 1.69

Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies. Blood (2011) 1.67

Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status. Leukemia (2007) 1.52

Low mRNA expression of the apoptosis-related genes CASP3, CASP8, and FAS is associated with low induction treatment response in childhood acute lymphoblastic leukemia (ALL). Pediatr Blood Cancer (2010) 1.43

Molecular genetics of B-precursor acute lymphoblastic leukemia. J Clin Invest (2012) 1.38

Identification of gene expression profiles that segregate patients with childhood leukemia. Clin Cancer Res (2002) 1.16

Mutations in apoptosis genes: a pathogenetic factor for human disease. Mutat Res (2001) 0.97

mRNA expression profile of multidrug-resistant genes in acute lymphoblastic leukemia of children, a prognostic value for ABCA3 and ABCA2. Cancer Biol Ther (2013) 0.93

Expression and prognostic significance of the apoptotic genes BCL2L13, Livin, and CASP8AP2 in childhood acute lymphoblastic leukemia. Leuk Res (2010) 0.92

Gene expression overlap affects karyotype prediction in pediatric acute lymphoblastic leukemia. Leukemia (2007) 0.91

Targeting paediatric acute lymphoblastic leukaemia: novel therapies currently in development. Br J Haematol (2010) 0.86

Relapse of acute lymphoblastic leukemia in children in the context of microarray analyses. Arch Immunol Ther Exp (Warsz) (2011) 0.85

Potential of gene expression profiling in the management of childhood acute lymphoblastic leukemia. Paediatr Drugs (2007) 0.80

Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy. Int J Oncol (2007) 0.78