Unlocking the Sporicidal Potential of Ethanol: Induced Sporicidal Activity of Ethanol against Clostridium difficile and Bacillus Spores under Altered Physical and Chemical Conditions.

Chemical and Stress Resistances of Clostridium difficile Spores and Vegetative Cells. Front Microbiol (2016) 0.79

A Cumulative Spore Killing Approach: Synergistic Sporicidal Activity of Dilute Peracetic Acid and Ethanol at Low pH Against Clostridium difficile and Bacillus subtilis Spores. Open Forum Infect Dis (2015) 0.75

A Quaternary Ammonium Disinfectant Containing Germinants Reduces Clostridium difficile Spores on Surfaces by Inducing Susceptibility to Environmental Stressors. Open Forum Infect Dis (2016) 0.75

A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med (2005) 16.59

Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev (1999) 10.44

Guideline for Hand Hygiene in Health-Care Settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America. MMWR Recomm Rep (2002) 6.97

Denatured states of proteins. Annu Rev Biochem (1991) 4.86

Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents. Clin Infect Dis (2007) 4.77

Bile salts and glycine as cogerminants for Clostridium difficile spores. J Bacteriol (2008) 3.37

Efficacy of handrubbing with alcohol based solution versus standard handwashing with antiseptic soap: randomised clinical trial. BMJ (2002) 3.29

The denaturation of proteins. Part V: Denaturation by acid. Biochem J (1929) 2.99

SENSITIZATION OF BACTERIAL SPORES TO LYSOZYME AND TO HYDROGEN PEROXIDE WITH AGENTS WHICH RUPTURE DISULPHIDE BONDS. J Gen Microbiol (1963) 2.96

Epidemiologic background of hand hygiene and evaluation of the most important agents for scrubs and rubs. Clin Microbiol Rev (2004) 2.95

Control of an outbreak of infection with the hypervirulent Clostridium difficile BI strain in a university hospital using a comprehensive "bundle" approach. Clin Infect Dis (2007) 2.90

I will survive: DNA protection in bacterial spores. Trends Microbiol (2007) 2.40

Handwashing practices for the prevention of nosocomial infections. Ann Intern Med (1975) 2.36

No time for handwashing!? Handwashing versus alcoholic rub: can we afford 100% compliance? Infect Control Hosp Epidemiol (1997) 2.19

Clostridium difficile spore biology: sporulation, germination, and spore structural proteins. Trends Microbiol (2014) 1.73

Hand hygiene with soap and water is superior to alcohol rub and antiseptic wipes for removal of Clostridium difficile. Infect Control Hosp Epidemiol (2009) 1.70

Use of multilocus variable number of tandem repeats analysis genotyping to determine the role of asymptomatic carriers in Clostridium difficile transmission. Clin Infect Dis (2013) 1.58

Bacterial resistance to disinfectants: present knowledge and future problems. J Hosp Infect (1999) 1.49

Effective and reduced-cost modified selective medium for isolation of Clostridium difficile. J Clin Microbiol (2008) 1.48

The pathogenicity of Clostridium difficile. Clin Microbiol Infect (2001) 1.30

Natural skin surface pH is on average below 5, which is beneficial for its resident flora. Int J Cosmet Sci (2006) 1.28

Bacterial spore structures and their protective role in biocide resistance. J Appl Microbiol (2012) 1.18

Efficacy of selected hand hygiene agents used to remove Bacillus atrophaeus (a surrogate of Bacillus anthracis) from contaminated hands. JAMA (2003) 1.07

Moist-heat resistance, spore aging, and superdormancy in Clostridium difficile. Appl Environ Microbiol (2011) 1.01

Functional characterization of Clostridium difficile spore coat proteins. J Bacteriol (2013) 0.98

Use of alcohol hand sanitizer as an infection control strategy in an acute care facility. Am J Infect Control (2003) 0.97

The role of electrostatics in protein-protein interactions of a monoclonal antibody. Mol Pharm (2014) 0.92

Novel strategies for enhanced removal of persistent Bacillus anthracis surrogates and Clostridium difficile spores from skin. PLoS One (2013) 0.89

Effectiveness of hand hygiene for removal of Clostridium difficile spores from hands. Infect Control Hosp Epidemiol (2013) 0.84

The sporicidal activity and inactivation of chlorhexidine gluconate in aqueous and alcoholic solution. J Appl Bacteriol (1987) 0.81

A randomized trial of soap and water hand wash versus alcohol hand rub for removal of Clostridium difficile spores from hands of patients. Infect Control Hosp Epidemiol (2013) 0.79

[Studies on the denaturation of proteins. I. Auto-oxidation of proteins in alkaline medium]. Bull Soc Chim Biol (Paris) (1953) 0.79

Induced sporicidal activity of chlorhexidine against Clostridium difficile spores under altered physical and chemical conditions. PLoS One (2015) 0.78

Low-pH activation of Bacillus cereus spores. J Bacteriol (1970) 0.77

Metabolomics analysis identifies intestinal microbiota-derived biomarkers of colonization resistance in clindamycin-treated mice. PLoS One (2014) 0.95

Triggering germination represents a novel strategy to enhance killing of Clostridium difficile spores. PLoS One (2010) 0.93

Architecture and assembly of the Bacillus subtilis spore coat. PLoS One (2014) 0.81

Induced sporicidal activity of chlorhexidine against Clostridium difficile spores under altered physical and chemical conditions. PLoS One (2015) 0.78

The GerW protein is not involved in the germination of spores of Bacillus species. PLoS One (2015) 0.75