Published in Expert Opin Biol Ther on July 17, 2015
Interleukin-10-deficient mice develop chronic enterocolitis. Cell (1993) 22.57
Plant products as antimicrobial agents. Clin Microbiol Rev (1999) 18.15
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med (2007) 15.17
What works? Interventions for maternal and child undernutrition and survival. Lancet (2008) 13.89
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science (2007) 12.79
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med (2007) 11.82
A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature (1995) 11.18
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun (1998) 7.86
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med (2007) 5.96
GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell (2006) 4.98
Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell (2007) 4.66
Dietary intake and bioavailability of polyphenols. J Nutr (2000) 4.49
Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature (1995) 3.90
Overview of retinoid metabolism and function. J Neurobiol (2006) 3.19
Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells. Gut (2009) 2.75
Vitamin A, infection, and immune function. Annu Rev Nutr (2001) 2.75
Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity. Nature (2014) 2.26
Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovita): a randomised, double-blind, placebo-controlled trial. Lancet (2014) 2.09
Vitamin A metabolism: an update. Nutrients (2011) 1.99
Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice. Cancer Res (1994) 1.91
A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer. Int J Cancer (2007) 1.76
Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course. J Immunol (1995) 1.76
Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea. Proc Natl Acad Sci U S A (1999) 1.72
In vitamin A deficiency multiple mechanisms establish a regulatory T helper cell imbalance with excess Th1 and insufficient Th2 function. J Immunol (1994) 1.67
Intake of flavonoids and lung cancer. J Natl Cancer Inst (2000) 1.67
Mechanisms involved in the intestinal digestion and absorption of dietary vitamin A. J Nutr (2001) 1.60
Tea polyphenols decrease serum levels of prostate-specific antigen, hepatocyte growth factor, and vascular endothelial growth factor in prostate cancer patients and inhibit production of hepatocyte growth factor and vascular endothelial growth factor in vitro. Cancer Prev Res (Phila) (2009) 1.56
Evidence for a lecithin-retinol acyltransferase activity in the rat small intestine. J Biol Chem (1988) 1.53
Dietary flavonoids and the risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev (2007) 1.50
Randomized clinical trial of brewed green and black tea in men with prostate cancer prior to prostatectomy. Prostate (2014) 1.47
Quercetin suppresses proinflammatory cytokines production through MAP kinases andNF-kappaB pathway in lipopolysaccharide-stimulated macrophage. Mol Cell Biochem (2003) 1.45
Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis. J Immunol (2004) 1.44
Vitamin A enhances in vitro Th2 development via retinoid X receptor pathway. J Immunol (2002) 1.44
Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination. Cancer Res (2007) 1.43
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. J Leukoc Biol (2001) 1.41
Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases? Pharmacol Rev (2010) 1.39
Biochemical pathways of retinoid transport, metabolism, and signal transduction. Clin Immunol Immunopathol (1996) 1.38
In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid. J Immunol (2007) 1.37
A global clinical view on vitamin A and carotenoids. Am J Clin Nutr (2012) 1.37
Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea. Br J Pharmacol (2013) 1.33
Cutting edge: instructive role of peripheral tissue cells in the imprinting of T cell homing receptor patterns. J Immunol (2008) 1.29
Lymph node stromal cells support dendritic cell-induced gut-homing of T cells. J Immunol (2009) 1.26
Bile retinoids imprint intestinal CD103+ dendritic cells with the ability to generate gut-tropic T cells. Mucosal Immunol (2011) 1.26
Metabolism of vitamin A and its active metabolite all-trans-retinoic acid in small intestinal enterocytes. J Pharmacol Exp Ther (2000) 1.23
Abnormal regulation of IFN-gamma secretion in vitamin A deficiency. J Immunol (1991) 1.19
Antigen-presenting cell production of IL-10 inhibits T-helper 1 and 17 cell responses and suppresses colitis in mice. Gastroenterology (2011) 1.19
Direct and indirect effects of retinoic acid on human Th2 cytokine and chemokine expression by human T lymphocytes. BMC Immunol (2006) 1.16
Vitamin A supplementation: implications for morbidity and mortality in children. J Infect Dis (2000) 1.16
Vitamin A and immunity to viral, bacterial and protozoan infections. Proc Nutr Soc (1999) 1.15
Green tea polyphenols and metabolites in prostatectomy tissue: implications for cancer prevention. Cancer Prev Res (Phila) (2010) 1.12
Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin. Cancer Invest (2011) 1.11
9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic acid for secondary lymphedema. Circulation (2012) 1.11
Dietary flavonoid intake and lung cancer--a population-based case-control study. Cancer (2008) 1.10
In vivo and in vitro antiviral activity of hyperoside extracted from Abelmoschus manihot (L) medik. Acta Pharmacol Sin (2007) 1.07
TLR4 signaling inhibitory pathway induced by green tea polyphenol epigallocatechin-3-gallate through 67-kDa laminin receptor. J Immunol (2010) 1.07
Vitamin A deficiency increases the in vivo development of IL-10-positive Th2 cells and decreases development of Th1 cells in mice. J Nutr (2004) 1.06
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions. Proc Natl Acad Sci U S A (2014) 1.02
Quercetin inhibits LPS-induced nitric oxide and tumor necrosis factor-alpha production in murine macrophages. Int J Immunopharmacol (1999) 1.01
Protective mechanism of epigallocatechin-3-gallate against Helicobacter pylori-induced gastric epithelial cytotoxicity via the blockage of TLR-4 signaling. Helicobacter (2004) 1.00
Cyp26b1 regulates retinoic acid-dependent signals in T cells and its expression is inhibited by transforming growth factor-β. PLoS One (2011) 0.99
Induction of regulatory T cells by green tea polyphenol EGCG. Immunol Lett (2011) 0.99
Epicatechin, catechin, and dimeric procyanidins inhibit PMA-induced NF-kappaB activation at multiple steps in Jurkat T cells. FASEB J (2003) 0.98
Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation. Cancer Chemother Pharmacol (2011) 0.97
Unique lamina propria stromal cells imprint the functional phenotype of mucosal dendritic cells. Mucosal Immunol (2014) 0.97
Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. Mucosal Immunol (2014) 0.97
Inhibition by all-trans-retinoic acid of tumor necrosis factor and nitric oxide production by peritoneal macrophages. J Leukoc Biol (1994) 0.96
Activity of monomeric, dimeric, and trimeric flavonoids on NO production, TNF-alpha secretion, and NF-kappaB-dependent gene expression in RAW 264.7 macrophages. FEBS Lett (2000) 0.96
All-trans retinoic acid stimulates IL-2-mediated proliferation of human T lymphocytes: early induction of cyclin D3. J Immunol (2006) 0.96
Inhibition of adenovirus infection and adenain by green tea catechins. Antiviral Res (2003) 0.96
Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic beta-cell damage. Exp Mol Med (2003) 0.95
Green tea polyphenol extract attenuates inflammation in interleukin-2-deficient mice, a model of autoimmunity. J Nutr (2001) 0.95
Effect of vitamin A and zinc supplementation on gastrointestinal parasitic infections among Mexican children. Pediatrics (2007) 0.94
Immunosuppressive effect of quercetin on dendritic cell activation and function. J Immunol (2010) 0.94
Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol (2013) 0.94
Congenital malformations induced in rats by maternal vitamin A deficiency; defects of the eye. Arch Ophthal (1946) 0.92
Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children. J Nutr (2006) 0.92
Effects of vitamin A supplementation on intestinal barrier function, growth, total parasitic, and specific Giardia spp infections in Brazilian children: a prospective randomized, double-blind, placebo-controlled trial. J Pediatr Gastroenterol Nutr (2010) 0.92
Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence. World J Gastroenterol (2008) 0.91
Catechins inhibit angiotensin II-induced vascular smooth muscle cell proliferation via mitogen-activated protein kinase pathway. Exp Mol Med (2006) 0.91
Intake of specific carotenoids and flavonoids and the risk of lung cancer in women in Barcelona, Spain. Nutr Cancer (1998) 0.91
Comparison of in vitro antiviral activity of tea polyphenols against influenza A and B viruses and structure-activity relationship analysis. Fitoterapia (2013) 0.91
The flavonoid morin from Moraceae induces apoptosis by modulation of Bcl-2 family members and Fas receptor in HCT 116 cells. Int J Oncol (2015) 0.90
Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin. Br J Pharmacol (2006) 0.90
Enhancement of (-)-epigallocatechin-3-gallate and theaflavin-3-3'-digallate induced apoptosis by ascorbic acid in human lung adenocarcinoma SPC-A-1 cells and esophageal carcinoma Eca-109 cells via MAPK pathways. Biochem Biophys Res Commun (2013) 0.90
Tannic acid and quercetin display a therapeutic effect in atopic dermatitis via suppression of angiogenesis and TARC expression in Nc/Nga mice. J Invest Dermatol (2010) 0.89
Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-κB and MAPK/ERK mediated YB-1 activity in A2780/T cells. PLoS One (2013) 0.89
Epigallocatechin-3-gallate, constituent of green tea, suppresses the LPS-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and NF-kappaB. Biochem Biophys Res Commun (2004) 0.88
Prenatally acquired vitamin A deficiency alters innate immune responses to human rotavirus in a gnotobiotic pig model. J Immunol (2013) 0.88
Epigallocatechin-3-gallate induces growth inhibition and apoptosis of human anaplastic thyroid carcinoma cells through suppression of EGFR/ERK pathway and cyclin B1/CDK1 complex. J Surg Oncol (2011) 0.88
A role for all-trans-retinoic acid in the early steps of lymphatic vasculature development. J Vasc Res (2010) 0.88
Involvement of ERK and protein tyrosine phosphatase signaling pathways in EGCG-induced cyclooxygenase-2 expression in Raw 264.7 cells. Biochem Biophys Res Commun (2001) 0.87
Dietary supplementation with high dose of epigallocatechin-3-gallate promotes inflammatory response in mice. J Nutr Biochem (2011) 0.87
Epigallocatechin gallate inhibits intracellular survival of Listeria monocytogenes in macrophages. Biochem Biophys Res Commun (2007) 0.87
Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients. Radiat Res (2013) 0.86
Inhibition of influenza virus internalization by (-)-epigallocatechin-3-gallate. Antiviral Res (2013) 0.86
The intestinal micro-environment imprints stromal cells to promote efficient Treg induction in gut-draining lymph nodes. Mucosal Immunol (2013) 0.86
Procyanidin B2 induces Nrf2 translocation and glutathione S-transferase P1 expression via ERKs and p38-MAPK pathways and protect human colonic cells against oxidative stress. Eur J Nutr (2011) 0.85
IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2. J Immunol (2013) 0.85
A small molecule inhibits virion attachment to heparan sulfate- or sialic acid-containing glycans. J Virol (2014) 0.85
Legionella pneumophila replication in macrophages inhibited by selective immunomodulatory effects on cytokine formation by epigallocatechin gallate, a major form of tea catechins. Infect Immun (2001) 0.85