Published in Invest Ophthalmol Vis Sci on July 01, 2015
Ocular Hypertension Treatment Study (OHTS) (OHTS) | NCT00000125
The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol (2006) 25.47
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol (2002) 16.89
Identification of a gene that causes primary open angle glaucoma. Science (1997) 8.14
Adult-onset primary open-angle glaucoma caused by mutations in optineurin. Science (2002) 6.53
Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans. The Baltimore Eye Survey. Arch Ophthalmol (1991) 5.82
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Evaluation of retinal nerve fiber layer, optic nerve head, and macular thickness measurements for glaucoma detection using optical coherence tomography. Am J Ophthalmol (2005) 4.83
The epidemiology of open-angle glaucoma: a review. Am J Epidemiol (1983) 4.01
The Ocular Hypertension Treatment Study: design and baseline description of the participants. Arch Ophthalmol (1999) 3.30
Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. Nat Genet (2011) 2.42
Validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension. Ophthalmology (2006) 2.28
Variability of expert observers in evaluating the optic disc. Trans Am Ophthalmol Soc (1976) 2.25
Glaucoma diagnostic accuracy of ganglion cell-inner plexiform layer thickness: comparison with nerve fiber layer and optic nerve head. Ophthalmology (2012) 2.04
A genome-wide association study of optic disc parameters. PLoS Genet (2010) 1.87
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA. Hum Mol Genet (2011) 1.77
Copy number variations on chromosome 12q14 in patients with normal tension glaucoma. Hum Mol Genet (2011) 1.74
Psychiatric genetics: search for phenotypes. Trends Neurosci (1998) 1.68
Primary open-angle glaucoma genes. Eye (Lond) (2011) 1.60
Common genetic variants associated with open-angle glaucoma. Hum Mol Genet (2011) 1.58
Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. Hum Mol Genet (2010) 1.53
Pattern of glaucomatous neuroretinal rim loss. Ophthalmology (1993) 1.50
Racial differences in optic disc topography: baseline results from the confocal scanning laser ophthalmoscopy ancillary study to the ocular hypertension treatment study. Arch Ophthalmol (2004) 1.49
Quantitative evaluation of the optic nerve head in early glaucoma. Br J Ophthalmol (1998) 1.38
Common genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genet (2012) 1.33
Ranking of optic disc variables for detection of glaucomatous optic nerve damage. Invest Ophthalmol Vis Sci (2000) 1.32
Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. Hum Mol Genet (2011) 1.29
The Ocular Hypertension Treatment Study: reproducibility of cup/disk ratio measurements over time at an optic disc reading center. Am J Ophthalmol (2002) 1.27
Current concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatment. Eye (Lond) (2011) 1.24
Diagnosing preperimetric glaucoma with spectral domain optical coherence tomography. Ophthalmology (2012) 1.22
The Advanced Glaucoma Intervention Study (AGIS): 10. Variability among academic glaucoma subspecialists in assessing optic disc notching. Trans Am Ophthalmol Soc (2001) 1.20
The path to open-angle glaucoma gene discovery: endophenotypic status of intraocular pressure, cup-to-disc ratio, and central corneal thickness. Invest Ophthalmol Vis Sci (2010) 1.18
Fast detection of the optic disc and fovea in color fundus photographs. Med Image Anal (2009) 1.10
Shape analysis of the peripapillary RPE layer in papilledema and ischemic optic neuropathy. Invest Ophthalmol Vis Sci (2011) 1.07
Genome-wide association study of primary open angle glaucoma risk and quantitative traits. Mol Vis (2012) 1.01
The spatial pattern of neuroretinal rim loss in ocular hypertension. Invest Ophthalmol Vis Sci (2009) 0.97
Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations. Hum Mol Genet (2011) 0.96
Genetics of primary open angle glaucoma. Jpn J Ophthalmol (2013) 0.94
Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Genet Epidemiol (2015) 0.92
Size of the physiologic cup of the optic nerve head. hereditary and environmental factors. Arch Ophthalmol (1975) 0.90
Optic disc morphology--rethinking shape. Prog Retin Eye Res (2009) 0.90
Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nat Commun (2014) 0.90
The accuracy and clinical application of predictive models for primary open-angle glaucoma in ocular hypertensive individuals. Ophthalmology (2008) 0.85
Genetic investigation into the endophenotypic status of central corneal thickness and optic disc parameters in relation to open-angle glaucoma. Am J Ophthalmol (2012) 0.85
Robust multiscale stereo matching from fundus images with radiometric differences. IEEE Trans Pattern Anal Mach Intell (2011) 0.85
Population-based evaluation of retinal nerve fiber layer, retinal ganglion cell layer, and inner plexiform layer as a diagnostic tool for glaucoma. Invest Ophthalmol Vis Sci (2014) 0.84
Automated quantification of inherited phenotypes from color images: a twin study of the variability of optic nerve head shape. Invest Ophthalmol Vis Sci (2010) 0.82
A geometric morphometric assessment of the optic cup in glaucoma. Exp Eye Res (2010) 0.79
Optical coherence tomography shape analysis of the peripapillary retinal pigment epithelium layer in presumed optic nerve sheath meningiomas. J Neuroophthalmol (2014) 0.78
External validation of the OHTS-EGPS model for predicting the 5-year risk of open-angle glaucoma in ocular hypertensives. Br J Ophthalmol (2013) 0.78
Evaluation of the significance of some diagnostic parameters in making an early diagnose of primary open-angle glaucoma. Med Sci Monit (2012) 0.76
DNA copy number variants of known glaucoma genes in relation to primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2014) 0.80
A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. Invest Ophthalmol Vis Sci (2016) 0.76
Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses. Invest Ophthalmol Vis Sci (2016) 0.75