Published in Hum Mol Genet on July 21, 2015
The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse. J Neurosci (2016) 0.76
The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors. Elife (2017) 0.75
Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus. Front Genet (2017) 0.75
Function and regulation of human copper-transporting ATPases. Physiol Rev (2007) 3.38
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci U S A (2002) 3.28
Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking. EMBO J (1996) 3.04
Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J Neurochem (1997) 2.62
Confirming unexpressed genotypes for schizophrenia. Risks in the offspring of Fischer's Danish identical and fraternal discordant twins. Arch Gen Psychiatry (1989) 2.57
Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. J Clin Invest (2004) 2.46
Biochemistry of catecholamines. Annu Rev Biochem (1971) 2.22
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature (2008) 2.15
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell (2006) 2.11
Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo. Eur J Neurosci (2000) 2.06
ATP7A-related copper transport diseases-emerging concepts and future trends. Nat Rev Neurol (2011) 2.01
The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis. Science (2009) 1.87
Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation. Mol Psychiatry (2010) 1.80
Juvenile antioxidant treatment prevents adult deficits in a developmental model of schizophrenia. Neuron (2014) 1.77
Altered glutathione redox state in schizophrenia. Dis Markers (2006) 1.67
BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes. Mol Biol Cell (2006) 1.64
Genome-wide gene expression profiles of the developing mouse hippocampus. Proc Natl Acad Sci U S A (2001) 1.55
A haplotype at the DBH locus, associated with low plasma dopamine beta-hydroxylase activity, also associates with cocaine-induced paranoia. Mol Psychiatry (2000) 1.44
The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth. Mol Psychiatry (2009) 1.44
Genetics of schizophrenia: new findings and challenges. Annu Rev Genomics Hum Genet (2011) 1.41
Modulation of the cellular pharmacology of cisplatin and its analogs by the copper exporters ATP7A and ATP7B. Mol Pharmacol (2004) 1.41
Wilson's disease. Psychiatric symptoms in 195 cases. Arch Gen Psychiatry (1989) 1.31
Gene amplification of the Menkes (MNK; ATP7A) P-type ATPase gene of CHO cells is associated with copper resistance and enhanced copper efflux. Hum Mol Genet (1995) 1.29
Distinct and overlapping roles for AP-1 and GGAs revealed by the "knocksideways" system. Curr Biol (2012) 1.27
Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase. Neuropsychopharmacology (2010) 1.27
The promise of N-acetylcysteine in neuropsychiatry. Trends Pharmacol Sci (2013) 1.21
Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression. Hum Mol Genet (2009) 1.18
Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness. Proc Natl Acad Sci U S A (2013) 1.18
Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1. J Neurosci (2012) 1.18
Psychiatric aspects of Wilson disease: a review. Gen Hosp Psychiatry (2013) 1.17
Gene-environment interactions in severe mental illness. Front Psychiatry (2014) 1.09
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα. Mol Biol Cell (2013) 1.08
MEDNIK syndrome: a novel defect of copper metabolism treatable by zinc acetate therapy. Brain (2013) 1.07
Dominant psychiatric manifestations in Wilson's disease: a diagnostic and therapeutic challenge! J Neurol Sci (2007) 1.07
Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A "central hub" in schizophrenia pathophysiology? Schizophr Res (2014) 1.06
Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene. J Biol Chem (2004) 1.04
Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene. Mol Neurobiol (2011) 1.04
Dysbindin (DTNBP1, 6p22.3) is associated with childhood-onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS). J Autism Dev Disord (2005) 1.02
Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency. Hum Mol Genet (2009) 1.00
Behavioral and neurobiological changes in C57BL/6 mice exposed to cuprizone. Behav Neurosci (2009) 1.00
Gene expression profiling in chronic copper overload reveals upregulation of Prnp and App. Physiol Genomics (2004) 1.00
Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location. PLoS One (2011) 0.99
Genetic or epigenetic difference causing discordance between monozygotic twins as a clue to molecular basis of mental disorders. Mol Psychiatry (2005) 0.98
Dysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade. ASN Neuro (2011) 0.97
Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease. Neurobiol Dis (2007) 0.95
Identical but not the same: the value of discordant monozygotic twins in genetic research. Am J Med Genet B Neuropsychiatr Genet (2010) 0.95
COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A. Mol Biol Cell (2014) 0.93
Dysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53. Mol Psychiatry (2011) 0.93
Snapin is critical for presynaptic homeostatic plasticity. J Neurosci (2012) 0.92
Linkage analysis of plasma dopamine β-hydroxylase activity in families of patients with schizophrenia. Hum Genet (2011) 0.92
Modifiable risk factors for schizophrenia and autism--shared risk factors impacting on brain development. Neurobiol Dis (2012) 0.91
Isolation of labile multi-protein complexes by in vivo controlled cellular cross-linking and immuno-magnetic affinity chromatography. J Vis Exp (2010) 0.91
A case of psychosis in disulfiram treatment for alcoholism. Case Rep Psychiatry (2014) 0.90
Clusterin and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A and ATP7B. J Biol Chem (2011) 0.90
Dopamine beta-hydroxylase (DBH) gene and schizophrenia phenotypic variability: a genetic association study. Am J Med Genet B Neuropsychiatr Genet (2003) 0.90
Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification. Biochem J (2013) 0.89
Maternofetal and neonatal copper requirements revealed by enterocyte-specific deletion of the Menkes disease protein. Am J Physiol Gastrointest Liver Physiol (2012) 0.87
Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila. Proc Natl Acad Sci U S A (2011) 0.87
Pronounced paranoia as a result of cocaine-disulfiram interaction: case report and mode of action. J Clin Psychopharmacol (2009) 0.87
Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses. Neurotoxicology (2011) 0.86
Dopamine-beta-hydroxylase in the cerebrospinal fluid: relationship to disulfiram-induced psychosis. Biol Psychiatry (1979) 0.85
Dysbindin-1 gene contributes differentially to early- and adult-onset forms of functional psychosis. Am J Med Genet B Neuropsychiatr Genet (2011) 0.85
Determinants for simultaneous binding of copper and platinum to human chaperone Atox1: hitchhiking not hijacking. PLoS One (2013) 0.85
Peptidylglycine α-amidating monooxygenase heterozygosity alters brain copper handling with region specificity. J Neurochem (2013) 0.85
Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes. J Biol Chem (2014) 0.85
Impaired metabolic reactivity to oxidative stress in early psychosis patients. Schizophr Bull (2014) 0.85
Recovery of behavioral changes and compromised white matter in C57BL/6 mice exposed to cuprizone: effects of antipsychotic drugs. Front Behav Neurosci (2011) 0.84
Gene dosage in the dysbindin schizophrenia susceptibility network differentially affect synaptic function and plasticity. J Neurosci (2015) 0.83
Cuprizone short-term exposure: astrocytic IL-6 activation and behavioral changes relevant to psychosis. Neurobiol Dis (2013) 0.83
Chronic exposure of mutant DISC1 mice to lead produces sex-dependent abnormalities consistent with schizophrenia and related mental disorders: a gene-environment interaction study. Schizophr Bull (2013) 0.83
Drosophila melanogaster: a new model to study cisplatin-induced neurotoxicity. Neurobiol Dis (2011) 0.82
Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys. J Pharmacol Exp Ther (2014) 0.81
The copper hypothesis of schizophrenia: a review. Neurosci Biobehav Rev (1982) 0.81
Psychosis induced by the interaction between disulfiram and methylphenidate may be dose dependent. Subst Abus (2012) 0.81
The schizophrenia susceptibility gene dysbindin regulates dendritic spine dynamics. J Neurosci (2014) 0.81
Molecular basis of neurodegeneration and neurodevelopmental defects in Menkes disease. Neurobiol Dis (2015) 0.79
Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes. Transl Psychiatry (2013) 0.78
Transcriptional remodelling in response to changing copper levels in the Wilson and Menkes disease model of Saccharomyces cerevisiae. Mol Biosyst (2013) 0.78
Copper overload and deficiency both adversely affect the central nervous system of Drosophila. Metallomics (2014) 0.76
A case of disulfiram-methylphenidate interaction: implications for treatment. Am J Psychiatry (2007) 0.76
Psychotic symptoms after combined metronidazole-disulfiram use. J Clin Psychopharmacol (2013) 0.75
Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells. Mol Biol Cell (2011) 0.92
Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis. Mol Biol Cell (2013) 0.79
Molecular basis of neurodegeneration and neurodevelopmental defects in Menkes disease. Neurobiol Dis (2015) 0.79