A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults.

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Published in PLoS One on August 07, 2015

Authors

Juliet Mpendo1, Gaudensia Mutua2, Julien Nyombayire3, Rosine Ingabire3, Annet Nanvubya1, Omu Anzala2, Etienne Karita3, Peter Hayes4, Jakub Kopycinski4, Len Dally5, Drew Hannaman6, Michael A Egan7, John H Eldridge7, Kristen Syvertsen8, Jennifer Lehrman8, Beth Rasmussen8, Jill Gilmour4, Josephine H Cox8, Patricia E Fast8, Claudia Schmidt8

Author Affiliations

1: Uganda Virus Research Institute-IAVI, Entebbe, Uganda.
2: Kenya AIDS Vaccine Initiative, University of Nairobi, Nairobi, Kenya.
3: Projet San Francisco (PSF), Kigali, Rwanda.
4: IAVI, Human Immunology Laboratory, Imperial College, London, United Kingdom.
5: EMMES Corporation, Rockville, Maryland, United States of America.
6: ICHOR Medical Systems, Inc., San Diego, California, United States of America.
7: Profectus BioSciences, Inc., Tarrytown, New York, United States of America.
8: International AIDS Vaccine Initiative (IAVI), New York, New York, United States of America.

Associated clinical trials:

Safety and Immunogenicity Study of HIV-MAG Vaccine +/- IL-12 and Ad35-GRIN/ENV in HIV-uninfected Volunteers | NCT01496989

Safety & Immunogenicity of HIV Vaccines in Healthy Kenyan Adults (HIV-CORE 004) | NCT02099994

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