Role of systemic inflammation in cirrhosis: From pathogenesis to prognosis.

PubWeight™: 0.77‹?›

🔗 View Article (PMC 4528271)

Published in World J Hepatol on August 08, 2015

Authors

Melisa Dirchwolf1, Andrés Eduardo Ruf1

Author Affiliations

1: Melisa Dirchwolf, Hepatopatías Infecciosas, Hospital Francisco J Muñiz, Buenos Aires 1282, Argentina.

Articles citing this

Protein-protein interaction network analysis of cirrhosis liver disease. Gastroenterol Hepatol Bed Bench (2016) 0.84

Articles cited by this

Acute-phase proteins and other systemic responses to inflammation. N Engl J Med (1999) 18.25

Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol (2005) 6.22

Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. Gastroenterology (2013) 5.88

EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis. J Hepatol (2010) 4.55

Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis. Gastroenterology (2007) 4.09

Acute-on chronic liver failure. J Hepatol (2012) 3.74

Bacterial infections in cirrhosis: a position statement based on the EASL Special Conference 2013. J Hepatol (2014) 3.26

Bacterial translocation (BT) in cirrhosis. Hepatology (2005) 3.07

Local control of the immune response in the liver. Immunol Rev (2000) 3.01

Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis. Gastroenterology (2010) 3.00

Now there are many (stages) where before there was one: In search of a pathophysiological classification of cirrhosis. Hepatology (2010) 2.68

Patients with acute on chronic liver failure display "sepsis-like" immune paralysis. J Hepatol (2005) 2.66

Pathological bacterial translocation in liver cirrhosis. J Hepatol (2013) 2.65

Bacterial infections, sepsis, and multiorgan failure in cirrhosis. Semin Liver Dis (2008) 2.47

Neutrophil dysfunction in alcoholic hepatitis superimposed on cirrhosis is reversible and predicts the outcome. Hepatology (2007) 2.08

C-reactive protein predicts short-term mortality in patients with cirrhosis. J Hepatol (2012) 1.96

Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club. Gut (2005) 1.93

Natural history of portal hypertension in patients with cirrhosis. Clin Liver Dis (2001) 1.91

Evidence of neutrophil functional defect despite inflammation in stable cirrhosis. J Hepatol (2011) 1.90

Immune tolerance: what is unique about the liver. J Autoimmun (2009) 1.79

Natural history of decompensated hepatitis C virus-related cirrhosis. A study of 200 patients. J Hepatol (2004) 1.68

Hepatic encephalopathy in patients with acute decompensation of cirrhosis and acute-on-chronic liver failure. J Hepatol (2014) 1.64

The systemic inflammatory response syndrome in cirrhotic patients: relationship with their in-hospital outcome. J Hepatol (2009) 1.57

Prognostic value of C-reactive protein levels in patients with cirrhosis. Liver Transpl (2015) 1.52

Neutrophil-to-lymphocyte ratio predicts mortality in patients listed for liver transplantation. Liver Int (2014) 1.48

The C-reactive protein/albumin ratio, a novel inflammation-based prognostic score, predicts outcomes in patients with hepatocellular carcinoma. Ann Surg Oncol (2014) 1.36

A prospective study of the rate of progression in compensated, histologically advanced chronic hepatitis C. Hepatology (2011) 1.33

Model for end-stage liver disease score and systemic inflammatory response are major prognostic factors in patients with cirrhosis and acute functional renal failure. Hepatology (2007) 1.33

Bacterial translocation to mesenteric lymph nodes is increased in cirrhotic rats with ascites. Gastroenterology (1995) 1.28

Cirrhosis-associated immune dysfunction: distinctive features and clinical relevance. J Hepatol (2014) 1.25

Bacterial translocation in cirrhotic rats stimulates eNOS-derived NO production and impairs mesenteric vascular contractility. J Clin Invest (1999) 1.24

Gut microflora in the pathogenesis of the complications of cirrhosis. Best Pract Res Clin Gastroenterol (2004) 1.23

Toll-like receptor signaling and liver fibrosis. Gastroenterol Res Pract (2010) 1.20

Survival in infection-related acute-on-chronic liver failure is defined by extrahepatic organ failures. Hepatology (2014) 1.16

Prognostic value of C-reactive protein and neutrophil-to-lymphocyte ratio in patients with hepatocellular carcinoma. BMC Cancer (2013) 1.16

Acute-on-chronic liver failure: A new syndrome that will re-classify cirrhosis. J Hepatol (2015) 1.12

Leaky gut and the liver: a role for bacterial translocation in nonalcoholic steatohepatitis. World J Gastroenterol (2012) 1.10

Acute-on-chronic liver failure precipitated by hepatic injury is distinct from that precipitated by extrahepatic insults. Hepatology (2015) 1.06

Infectious complications of acute and chronic liver disease. Semin Respir Crit Care Med (2012) 1.05

The CLIF Consortium Acute Decompensation score (CLIF-C ADs) for prognosis of hospitalised cirrhotic patients without acute-on-chronic liver failure. J Hepatol (2014) 1.05

The immunological milieu of the liver. Semin Liver Dis (2007) 1.03

Immune dysfunction in cirrhosis. World J Gastroenterol (2014) 1.02

Human serum albumin, systemic inflammation, and cirrhosis. J Hepatol (2014) 1.01

Acute phase proteins for the diagnosis of bacterial infection and prediction of mortality in acute complications of cirrhosis. Ann Hepatol (2013) 0.98

Microbiota and the gut-liver axis: bacterial translocation, inflammation and infection in cirrhosis. World J Gastroenterol (2014) 0.97

Role of toll-like receptors in immune activation and tolerance in the liver. Front Immunol (2014) 0.96

Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK. Gastroenterology (2014) 0.95

Risk factors and outcome of bacterial infections in cirrhosis. World J Gastroenterol (2014) 0.95

Acute-on-chronic liver failure: a new clinical entity. Clin Gastroenterol Hepatol (2014) 0.94

Natural history of cirrhosis. Curr Gastroenterol Rep (2013) 0.94

Spontaneous bacterial peritonitis: The clinical challenge of a leaky gut and a cirrhotic liver. World J Hepatol (2015) 0.93

Classification of cirrhosis: the clinical use of HVPG measurements. Dis Markers (2011) 0.92

The role of gut-liver axis in the pathogenesis of liver cirrhosis and portal hypertension. Clin Mol Hepatol (2012) 0.91

Systemic inflammation is associated with increased intrahepatic resistance and mortality in alcohol-related acute-on-chronic liver failure. Liver Int (2014) 0.89

Gut-liver axis in liver cirrhosis: How to manage leaky gut and endotoxemia. World J Hepatol (2015) 0.88

Interaction between intestinal dendritic cells and bacteria translocated from the gut in rats with cirrhosis. Hepatology (2012) 0.88

Is it time to target gut dysbiosis and immune dysfunction in the therapy of hepatic encephalopathy? Expert Rev Gastroenterol Hepatol (2015) 0.88

Systemic inflammatory response syndrome in patients with liver cirrhosis. Arab J Gastroenterol (2011) 0.88

Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression. J Hepatol (2012) 0.87

Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection. PLoS One (2015) 0.86

[Significance of serum procalcitonin levels in the evaluation of severity and prognosis of patients with systemic inflammatory response syndrome]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue (2012) 0.82

Survey of serum procalcitonin in cirrhotic patients. Acta Med Iran (2013) 0.81

Frequency and severity of cirrhotic cardiomyopathy and its possible relationship with bacterial endotoxemia. Dig Dis Sci (2013) 0.80

C-reactive protein and model for end-stage liver disease score: Have we found the fifth element? Liver Transpl (2015) 0.80

Systemic Inflammatory Response Syndrome and MELD Score in Hospital Outcome of Patients with Liver Cirrhosis. Middle East J Dig Dis (2012) 0.79

The addition of C-reactive protein to validated staging systems improves their prognostic ability in patients with hepatocellular carcinoma. Oncology (2014) 0.79

Acute-on-chronic liver failure. Clin Liver Dis (2014) 0.79

Procalcitonin, and cytokines document a dynamic inflammatory state in non-infected cirrhotic patients with ascites. World J Gastroenterol (2014) 0.78

A novel prognostic score for acute-on-chronic hepatitis B liver failure. J Huazhong Univ Sci Technolog Med Sci (2015) 0.77

Impaired lymphocyte reactivity measured by immune function testing in untransplanted patients with cirrhosis. Clin Vaccine Immunol (2013) 0.76

Low eosinophil count predicts in-hospital mortality in cirrhosis with systemic inflammatory response syndrome. Eur J Gastroenterol Hepatol (2013) 0.76