Published in Curr Drug Metab on January 01, 2015
South Asian Medicinal Compounds as Modulators of Resistance to Chemotherapy and Radiotherapy. Cancers (Basel) (2016) 0.77
Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors. Pharmacol Res Perspect (2017) 0.75
Toxicological Implications of Mitochondrial Localization of CYP2E1. Toxicol Res (Camb) (2017) 0.75
p53, the cellular gatekeeper for growth and division. Cell (1997) 31.04
Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ (2004) 9.96
p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes. Mol Cell Biol (2000) 6.23
Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting. FEBS J (2010) 3.68
Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study. Int J Epidemiol (2013) 3.68
Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. JAMA (2006) 3.49
Estimates of acetaminophen (Paracetomal)-associated overdoses in the United States. Pharmacoepidemiol Drug Saf (2006) 3.06
CYP2E1 and oxidative liver injury by alcohol. Free Radic Biol Med (2007) 2.93
Asthma morbidity after the short-term use of ibuprofen in children. Pediatrics (2002) 2.90
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Proc Natl Acad Sci U S A (2009) 2.57
Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev (1997) 2.53
S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol (1999) 2.14
The calpain system and cancer. Nat Rev Cancer (2011) 2.10
Acetaminophen/paracetamol: A history of errors, failures and false decisions. Eur J Pain (2014) 2.04
PCNA on the crossroad of cancer. Biochem Soc Trans (2009) 2.03
The chemistry of garlic and onions. Sci Am (1985) 2.02
Intake of garlic and its bioactive components. J Nutr (2001) 1.97
Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver. Drug Metab Dispos (2005) 1.90
A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis. J Hepatol (2007) 1.82
Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis--a randomised clinical trial. J Hepatol (2005) 1.79
Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates. J Biol Chem (2008) 1.63
Role of Tat protein in HIV neuropathogenesis. Neurotox Res (2009) 1.60
Enzymatic mechanisms of ethanol oxidation in the brain. Alcohol Clin Exp Res (2006) 1.59
The modulation of ABC transporter-mediated multidrug resistance in cancer: a review of the past decade. Drug Resist Updat (2014) 1.54
Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radic Biol Med (2010) 1.47
Biological properties of garlic and garlic-derived organosulfur compounds. Environ Mol Mutagen (2009) 1.39
HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells. Brain Res (2005) 1.39
Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression. Toxicol Appl Pharmacol (1998) 1.39
Garlic [Allium sativum]: a review of its potential use as an anti-cancer agent. Curr Cancer Drug Targets (2003) 1.36
Molecular mechanisms of alcoholic liver disease: innate immunity and cytokines. Alcohol Clin Exp Res (2011) 1.35
Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis. J Hepatol (2012) 1.35
Contribution to characterization of oxidative stress in HIV/AIDS patients. Pharmacol Res (2003) 1.35
Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat. Am J Physiol Gastrointest Liver Physiol (2001) 1.32
Magnetic nanoformulation of azidothymidine 5'-triphosphate for targeted delivery across the blood-brain barrier. Int J Nanomedicine (2010) 1.31
CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation. Exp Mol Pathol (2006) 1.31
Phase II drug metabolizing enzymes. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub (2010) 1.31
Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2. Drug Metab Dispos (2007) 1.29
Oxidative damage induced by the injection of HIV-1 Tat protein in the rat striatum. Neurosci Lett (2001) 1.23
Activation of the oxidative stress pathway by HIV-1 Vpr leads to induction of hypoxia-inducible factor 1alpha expression. J Biol Chem (2009) 1.21
Garlic consumption and cancer prevention: meta-analyses of colorectal and stomach cancers. Am J Clin Nutr (2000) 1.21
4-hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells. Toxicol Appl Pharmacol (2006) 1.19
Cytochrome P450 2E1: its clinical and toxicological role. J Clin Pharm Ther (2000) 1.18
Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol. Cancer Res (2001) 1.17
Metabolism of theophylline by cDNA-expressed human cytochromes P-450. Br J Clin Pharmacol (1995) 1.16
Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode. J Biol Chem (2010) 1.11
Inhibition of cytochrome P-450 2E1 by diallyl sulfide and its metabolites. Chem Res Toxicol (1992) 1.10
Regulation of cytochrome P450 2e1 expression by ethanol: role of oxidative stress-mediated pkc/jnk/sp1 pathway. Cell Death Dis (2013) 1.08
The role of the hepatic microsomal ethanol oxidizing system (MEOS) for ethanol metabolism in vivo. J Pharmacol Exp Ther (1972) 1.08
Effect of diallyl sulfide on rat liver microsomal nitrosamine metabolism and other monooxygenase activities. Cancer Res (1988) 1.07
Pathogenesis of alcoholic liver disease: role of oxidative metabolism. World J Gastroenterol (2014) 1.06
HIV-1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein-1 (Mrp1) in glial cells. J Neurochem (2008) 1.06
Ebselen prevents early alcohol-induced liver injury in rats. Free Radic Biol Med (2001) 1.06
HIV-dementia, Tat-induced oxidative stress, and antioxidant therapeutic considerations. Brain Res Brain Res Rev (2005) 1.05
Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors. Hepatology (1995) 1.05
Oxidative stress and therapeutic approaches in HIV dementia. Antioxid Redox Signal (2006) 1.04
Acetaminophen hepatotoxicity: an updated review. Arch Toxicol (2014) 1.04
Reduction of toxic metabolite formation of acetaminophen. Biochem Biophys Res Commun (2002) 1.04
Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression. Hepatology (2002) 1.04
Molecular mechanism of phase I and phase II drug-metabolizing enzymes: implications for detoxification. Int Rev Cytol (2007) 1.03
Allopurinol prevents early alcohol-induced liver injury in rats. J Pharmacol Exp Ther (2000) 1.03
HIV-1 gp120-induced injury to the blood-brain barrier: role of metalloproteinases 2 and 9 and relationship to oxidative stress. J Neuropathol Exp Neurol (2010) 1.03
Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats. Eur J Pharmacol (2009) 1.03
The alcohol-inducible form of cytochrome P450 (CYP 2E1): role in toxicology and regulation of expression. Arch Pharm Res (2000) 1.02
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks. J Med Chem (2012) 1.01
Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1. Toxicol Appl Pharmacol (2005) 1.01
Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance. Am J Physiol Endocrinol Metab (2011) 1.01
Activating the Nrf2-mediated antioxidant response element restores barrier function in the alveolar epithelium of HIV-1 transgenic rats. Am J Physiol Lung Cell Mol Physiol (2013) 1.01
CYP2E1 and risk of chemically mediated cancers. Expert Opin Drug Metab Toxicol (2010) 1.01
Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells. Apoptosis (2007) 1.00
Enhancing the delivery of anti retroviral drug "Saquinavir" across the blood brain barrier using nanoparticles. Curr HIV Res (2010) 0.99
The role of ethanol metabolism in development of alcoholic steatohepatitis in the rat. Alcohol (2010) 0.98
Diallyl sulfide attenuates bleomycin-induced pulmonary fibrosis: critical role of iNOS, NF-kappaB, TNF-alpha and IL-1beta. Life Sci (2008) 0.97
Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor. Drug Metab Dispos (2003) 0.97
Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic. J Nutr (2001) 0.97
Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells. J Pharmacol Exp Ther (1995) 0.97
Molecular mechanisms for the anti-cancer effects of diallyl disulfide. Food Chem Toxicol (2013) 0.97
HIV gp120- and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1. Cell Death Dis (2013) 0.96
The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism. PLoS One (2011) 0.96
Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells. J Gastroenterol Hepatol (2006) 0.95
Genome-scale methylation analysis of Parkinson's disease patients' brains reveals DNA hypomethylation and increased mRNA expression of cytochrome P450 2E1. Neurogenetics (2012) 0.95
Hepatocyte circadian clock controls acetaminophen bioactivation through NADPH-cytochrome P450 oxidoreductase. Proc Natl Acad Sci U S A (2014) 0.93
Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary. Anticancer Res (2007) 0.93
Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1beta. Osteoarthritis Cartilage (2008) 0.93
Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo. Phytomedicine (2012) 0.92
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. Drug Metab Dispos (2003) 0.92
Metabolism of garlic constituents in the isolated perfused rat liver. Planta Med (1992) 0.92
Opioids in the management of HIV-related pain. Pain Physician (2012) 0.91
Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: role of cytochrome P450 isozymes. Expert Opin Drug Metab Toxicol (2012) 0.91
Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions. Environ Toxicol (2011) 0.90
Pretranslational activation of cytochrome P450IIE during ketosis induced by a high fat diet. Mol Pharmacol (1992) 0.89
Drug-drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems. Expert Opin Drug Metab Toxicol (2014) 0.89
Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1,3-dimethyluric acid formation. Eur J Pharm Sci (2005) 0.89
Differential effects of ethanol on spectral binding and inhibition of cytochrome P450 3A4 with eight protease inhibitors antiretroviral drugs. Alcohol Clin Exp Res (2011) 0.88
Mechanisms of protection against aflatoxin B(1) genotoxicity in rats treated by organosulfur compounds from garlic. Carcinogenesis (2002) 0.88
Anti-HIV-1 nanotherapeutics: promises and challenges for the future. Int J Nanomedicine (2012) 0.88
Metabolism of the chemoprotective agent diallyl sulfide to glutathione conjugates in rats. Chem Res Toxicol (1997) 0.87
Association of CYP2E1 gene polymorphism with predisposition to cancer development. Exp Oncol (2005) 0.87
Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mouse lung. Carcinogenesis (1992) 0.87
Co-medications that modulate liver injury and repair influence clinical outcome of acetaminophen-associated liver injury. Clin Gastroenterol Hepatol (2009) 0.87
Synergistic growth inhibition of mouse skin tumors by pomegranate fruit extract and diallyl sulfide: evidence for inhibition of activated MAPKs/NF-κB and reduced cell proliferation. Food Chem Toxicol (2011) 0.87
Accurate whole human genome sequencing using reversible terminator chemistry. Nature (2008) 90.20
Structural basis for antagonism and resistance of bicalutamide in prostate cancer. Proc Natl Acad Sci U S A (2005) 2.89
In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18). J Nucl Med (2010) 2.72
Nitric oxide regulation of myocardial contractility and calcium cycling: independent impact of neuronal and endothelial nitric oxide synthases. Circ Res (2003) 2.44
Structural grading of foveal hypoplasia using spectral-domain optical coherence tomography a predictor of visual acuity? Ophthalmology (2011) 2.42
Status of PharmD/PhD programs in colleges of pharmacy: the University of Tennessee dual PharmD/PhD program. Am J Pharm Educ (2006) 2.35
Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1. J Biol Chem (2006) 2.32
Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology (2006) 2.15
Mathematical modelling and the control of lymphatic filariasis. Lancet Infect Dis (2004) 2.13
Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nat Immunol (2013) 1.95
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis. Proc Natl Acad Sci U S A (2009) 1.91
Sex differences in striatal dopamine release in healthy adults. Biol Psychiatry (2006) 1.87
The guanine cation radical: investigation of deprotonation states by ESR and DFT. J Phys Chem B (2006) 1.83
Universal plant DNA barcode loci may not work in complex groups: a case study with Indian berberis species. PLoS One (2010) 1.73
Pharmacodynamics of selective androgen receptor modulators. J Pharmacol Exp Ther (2003) 1.73
Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users. Synapse (2008) 1.66
Alterations of central dopamine receptors before and after gastric bypass surgery. Obes Surg (2009) 1.65
Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor. Mol Pharmacol (2003) 1.65
NMR Fourier zeugmatography. 1975. J Magn Reson (2011) 1.64
Design, synthesis, and biological characterization of metabolically stable selective androgen receptor modulators. J Med Chem (2004) 1.64
Size-dependent localization and penetration of ultrasmall gold nanoparticles in cancer cells, multicellular spheroids, and tumors in vivo. ACS Nano (2012) 1.62
Synthesis and antiproliferative activity of 2-aryl-4-oxo-thiazolidin-3-yl-amides for prostate cancer. Bioorg Med Chem Lett (2004) 1.57
B cells activated by lipopolysaccharide, but not by anti-Ig and anti-CD40 antibody, induce anergy in CD8+ T cells: role of TGF-beta 1. J Immunol (2003) 1.56
Structural basis for accommodation of nonsteroidal ligands in the androgen receptor. J Biol Chem (2005) 1.54
An overview of tubulin inhibitors that interact with the colchicine binding site. Pharm Res (2012) 1.49
Compound 49b prevents diabetes-induced apoptosis through increased IGFBP-3 levels. Invest Ophthalmol Vis Sci (2012) 1.46
The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury. Gastroenterology (2007) 1.42
Pharmacology, pharmacokinetics, and metabolism of acetothiolutamide, a novel nonsteroidal agonist for the androgen receptor. J Pharmacol Exp Ther (2003) 1.41
Targeted cryoablation of the prostate: 7-year outcomes in the primary treatment of prostate cancer. Urology (2002) 1.41
Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin. J Med Chem (2005) 1.40
Nonsteroidal selective androgen receptor modulators enhance female sexual motivation. J Pharmacol Exp Ther (2010) 1.39
Novel nonsteroidal ligands with high binding affinity and potent functional activity for the androgen receptor. Eur J Med Chem (2002) 1.39
Single-file diffusion of confined water inside SWNTs: an NMR study. ACS Nano (2010) 1.38
Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size. Diabetes (2011) 1.37
A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor. J Med Chem (2004) 1.35
Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. J Exp Med (2010) 1.33
The functional significance of foveal abnormalities in albinism measured using spectral-domain optical coherence tomography. Ophthalmology (2011) 1.32
11C-JHU75528: a radiotracer for PET imaging of CB1 cannabinoid receptors. J Nucl Med (2006) 1.32
Application of plasmonic bowtie nanoantenna arrays for optical trapping, stacking, and sorting. Nano Lett (2012) 1.31
Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: clues from an in vivo neurochemistry study with PET. Neuropsychopharmacology (2007) 1.30
Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors. Mol Cell Biol (2010) 1.28
Increased viral replication in simian immunodeficiency virus/simian-HIV-infected macaques with self-administering model of chronic alcohol consumption. J Acquir Immune Defic Syndr (2005) 1.28
High-resolution in vivo imaging in achromatopsia. Ophthalmology (2011) 1.27
Selective androgen receptor modulator treatment improves muscle strength and body composition and prevents bone loss in orchidectomized rats. Endocrinology (2005) 1.27
Phenotypic & molecular characterization of AmpC β-lactamases among Escherichia coli, Klebsiella spp. & Enterobacter spp. from five Indian Medical Centers. Indian J Med Res (2012) 1.27
Discovery of 4-substituted methoxybenzoyl-aryl-thiazole as novel anticancer agents: synthesis, biological evaluation, and structure-activity relationships. J Med Chem (2009) 1.27
A selective androgen receptor modulator for hormonal male contraception. J Pharmacol Exp Ther (2004) 1.25
Emerging trends in oral delivery of peptide and protein drugs. Crit Rev Ther Drug Carrier Syst (2003) 1.25
Retracted Role of casein phosphopeptide amorphous calcium phosphate in remineralization of white spot lesions and inhibition of Streptococcus mutans? J Conserv Dent (2013) 1.25
Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors. Mol Pharmacol (2003) 1.25
Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3beta, 17alpha, 20-triol and their bioactivity in melanoma cells. Steroids (2008) 1.24
Modulation by morphine of viral set point in rhesus macaques infected with simian immunodeficiency virus and simian-human immunodeficiency virus. J Virol (2004) 1.23
Effect of base stacking on the acid-base properties of the adenine cation radical [A*+] in solution: ESR and DFT studies. J Am Chem Soc (2008) 1.22
Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents. J Med Chem (2010) 1.21
Reversal of experimental diabetes by multiple bone marrow transplantation. Biochem Biophys Res Commun (2005) 1.20
Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit. J Med Chem (2009) 1.20
Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands. Bioorg Med Chem Lett (2005) 1.19
Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA(1), p42 and p38alpha. Biochim Biophys Acta (2007) 1.18
Poly-(L)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data. Adv Exp Med Biol (2003) 1.18
Chronic morphine exposure causes pronounced virus replication in cerebral compartment and accelerated onset of AIDS in SIV/SHIV-infected Indian rhesus macaques. Virology (2006) 1.18
In silico identification of candidate drug and vaccine targets from various pathways in Neisseria gonorrhoeae. In Silico Biol (2009) 1.17
Huntington's disease: pathogenesis to animal models. Pharmacol Rep (2010) 1.16
Morphine enhances Tat-induced activation in murine microglia. J Neurovirol (2009) 1.16
Association of amphetamine-induced striatal dopamine release and cortisol responses to psychological stress. Neuropsychopharmacology (2007) 1.16
VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease. J Neurochem (2007) 1.15
The implications of lighted ureteral stenting in laparoscopic colectomy. JSLS (2002) 1.14
Photo-induced hole transfer from base to sugar in DNA: relationship to primary radiation damage. Radiat Res (2006) 1.14
Horseshoe kidneys: an underutilized resource in kidney transplant. Exp Clin Transplant (2010) 1.13
Cocaine-mediated enhancement of virus replication in macrophages: implications for human immunodeficiency virus-associated dementia. J Neurovirol (2007) 1.13
HIV-1 gp120 induces expression of IL-6 through a nuclear factor-kappa B-dependent mechanism: suppression by gp120 specific small interfering RNA. PLoS One (2011) 1.13
Solid dispersion as an approach for bioavailability enhancement of poorly water-soluble drug ritonavir. AAPS PharmSciTech (2010) 1.12
Prototropic equilibria in DNA containing one-electron oxidized GC: intra-duplex vs. duplex to solvent deprotonation. Phys Chem Chem Phys (2010) 1.12
Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery. Biomacromolecules (2002) 1.12
Long-term exposure to oral methylphenidate or dl-amphetamine mixture in peri-adolescent rhesus monkeys: effects on physiology, behavior, and dopamine system development. Neuropsychopharmacology (2012) 1.11
A comprehensive approach to faculty development. Am J Pharm Educ (2006) 1.11
Open source drug discovery--a new paradigm of collaborative research in tuberculosis drug development. Tuberculosis (Edinb) (2011) 1.11
Evidence that glycoprotein 96 (B2), a stress protein, functions as a Th2-specific costimulatory molecule. J Immunol (2002) 1.11
Selective androgen receptor modulators in preclinical and clinical development. Nucl Recept Signal (2008) 1.11
The para substituent of S-3-(phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamides is a major structural determinant of in vivo disposition and activity of selective androgen receptor modulators. J Pharmacol Exp Ther (2005) 1.10
Analysis of the structural consensus of the zinc coordination centers of metalloprotein structures. Biochim Biophys Acta (2007) 1.10
Impulsivity and chronic stress are associated with amphetamine-induced striatal dopamine release. Neuroimage (2007) 1.09
Design, synthesis, and SAR studies of 4-substituted methoxylbenzoyl-aryl-thiazoles analogues as potent and orally bioavailable anticancer agents. J Med Chem (2011) 1.09
Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives. Photochem Photobiol Sci (2008) 1.09
PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets. Proc Natl Acad Sci U S A (2010) 1.08
Free radical scavenging property and diuretic effect of triglize, a polyherbal formulation in experimental models. J Pharmacol Pharmacother (2010) 1.08
HIV-1 gp120-mediated increases in IL-8 production in astrocytes are mediated through the NF-κB pathway and can be silenced by gp120-specific siRNA. J Neuroinflammation (2010) 1.08
Photoexcitation of adenine cation radical [A*+] in the near UV-vis region produces sugar radicals in adenosine and in its nucleotides. J Phys Chem B (2008) 1.08
Nonhuman primate models of NeuroAIDS. J Neurovirol (2008) 1.07
Micellar delivery of bicalutamide and embelin for treating prostate cancer. Pharm Res (2009) 1.07
Laparoscopic repair of a right para duodenal hernia. J Minim Access Surg (2009) 1.06
Influence of hydration on proton transfer in the guanine-cytosine radical cation (G*+-C) base pair: a density functional theory study. J Phys Chem B (2009) 1.06
Plasticity and stability of the visual system in human achiasma. Neuron (2012) 1.05
Neuroprotective effect of peroxiredoxin 6 against hypoxia-induced retinal ganglion cell damage. BMC Neurosci (2010) 1.04
Pharmacokinetic optimization of 4-substituted methoxybenzoyl-aryl-thiazole and 2-aryl-4-benzoyl-imidazole for improving oral bioavailability. Drug Metab Dispos (2011) 1.04
Steroidogenic enzyme AKR1C3 is a novel androgen receptor-selective coactivator that promotes prostate cancer growth. Clin Cancer Res (2013) 1.03
Involvement of metabotropic glutamate receptor 5, AKT/PI3K signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes. J Neuroinflammation (2012) 1.02
MAPK machinery in plants: recognition and response to different stresses through multiple signal transduction pathways. Plant Signal Behav (2010) 1.02
Successful anesthetic management of a child with blepharophimosis syndrome and atrial septal defect for reconstructive ocular surgery. J Anaesthesiol Clin Pharmacol (2011) 1.02
Single-cell-based image analysis of high-throughput cell array screens for quantification of viral infection. Cytometry A (2009) 1.02