Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia.

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Published in Blood on August 11, 2015

Authors

Seth E Karol1, Wenjian Yang2, Sara L Van Driest3, Tamara Y Chang1, Sue Kaste4, Erica Bowton5, Melissa Basford5, Lisa Bastarache6, Dan M Roden7, Joshua C Denny8, Eric Larsen9, Naomi Winick10, William L Carroll11, Cheng Cheng12, Deqing Pei12, Christian A Fernandez2, Chengcheng Liu2, Colton Smith2, Mignon L Loh13, Elizabeth A Raetz14, Stephen P Hunger15, Paul Scheet16, Sima Jeha1, Ching-Hon Pui1, William E Evans2, Meenakshi Devidas17, Leonard A Mattano18, Mary V Relling2

Author Affiliations

1: Department of Oncology and.
2: Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN;
3: Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN;
4: Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, TN; Department of Radiology, University of Tennessee, Memphis, TN;
5: Office of Research.
6: Department of Biomedical Informatics.
7: Department of Pharmacology, and Department of Medicine, Vanderbilt University Medical Center, Nashville, TN;
8: Department of Biomedical Informatics, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN;
9: Department of Pediatrics, Maine Medical Center, Portland, ME;
10: Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX;
11: Department of Pediatrics, New York University Langone Medical Center, New York, NY;
12: Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN;
13: Department of Pediatrics, University of California School of Medicine, San Francisco, CA;
14: Department of Pediatrics, University of Utah, Salt Lake City, UT;
15: Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA;
16: Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX;
17: Department of Biostatistics, Colleges of Medicine, Public Health and Health Professions, University of Florida, Gainesville, FL; and.
18: HARP Pharma Consulting, Mystic, CT.

Associated clinical trials:

Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia | NCT00137111

Dexamethasone Compared With Prednisone During Induction Therapy and MTX With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia | NCT00075725

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