Published in Brain Inj on August 14, 2015
Progesterone treatment reduces neuroinflammation, oxidative stress and brain damage and improves long-term outcomes in a rat model of repeated mild traumatic brain injury. J Neuroinflammation (2015) 0.87
Combination therapies for neurobehavioral and cognitive recovery after experimental traumatic brain injury: Is more better? Prog Neurobiol (2016) 0.84
The Controlled Cortical Impact Model: Applications, Considerations for Researchers, and Future Directions. Front Neurol (2016) 0.80
The effect of concomitant peripheral injury on traumatic brain injury pathobiology and outcome. J Neuroinflammation (2016) 0.79
Progesterone exerts neuroprotective effects and improves long-term neurologic outcome after intracerebral hemorrhage in middle-aged mice. Neurobiol Aging (2016) 0.78
Developing a Cognition Endpoint for Traumatic Brain Injury Clinical Trials. J Neurotrauma (2016) 0.77
Progesterone Treatment Shows Benefit in Female Rats in a Pediatric Model of Controlled Cortical Impact Injury. PLoS One (2016) 0.76
Effects of progesterone and vitamin D on outcome of patients with acute traumatic spinal cord injury; a randomized, double-blind, placebo controlled study. J Spinal Cord Med (2015) 0.75
How to Translate Time? The Temporal Aspect of Human and Rodent Biology. Front Neurol (2017) 0.75
Conjugated Linoleic Acid Administration Induces Amnesia in Male Sprague Dawley Rats and Exacerbates Recovery from Functional Deficits Induced by a Controlled Cortical Impact Injury. PLoS One (2017) 0.75
Progesterone improves long-term functional and histological outcomes after permanent stroke in older rats. Behav Brain Res (2016) 0.75
The Serum Changes of Neuron-Specific Enolase and Intercellular Adhesion Molecule-1 in Patients With Diffuse Axonal Injury Following Progesterone Administration: A Randomized Clinical Trial. Arch Trauma Res (2016) 0.75
Concussion As a Multi-Scale Complex System: An Interdisciplinary Synthesis of Current Knowledge. Front Neurol (2017) 0.75
Sexual dimorphism in the inflammatory response to traumatic brain injury. Glia (2017) 0.75
Repetitive and prolonged omega-3 fatty acid treatment after traumatic brain injury enhances long-term tissue restoration and cognitive recovery. Cell Transplant (2016) 0.75
Long-acting slow effective release antiretroviral therapy. Expert Opin Drug Deliv (2017) 0.75
Why most published research findings are false. PLoS Med (2005) 41.68
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A clinical trial of progesterone for severe traumatic brain injury. N Engl J Med (2014) 3.72
Classification of traumatic brain injury for targeted therapies. J Neurotrauma (2008) 3.58
Very early administration of progesterone for acute traumatic brain injury. N Engl J Med (2014) 3.20
Placebo-controlled trial of amantadine for severe traumatic brain injury. N Engl J Med (2012) 3.15
Flawed Self-Assessment: Implications for Health, Education, and the Workplace. Psychol Sci Public Interest (2004) 3.06
ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury. Ann Emerg Med (2006) 2.86
Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial. Crit Care (2008) 2.33
Effect of citicoline on functional and cognitive status among patients with traumatic brain injury: Citicoline Brain Injury Treatment Trial (COBRIT). JAMA (2012) 2.06
Analysis of data errors in clinical research databases. AMIA Annu Symp Proc (2008) 1.99
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Cheerio, laddie! Bidding farewell to the Glasgow Coma Scale. Ann Emerg Med (2011) 1.55
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Progesterone in experimental permanent stroke: a dose-response and therapeutic time-window study. Brain (2013) 1.49
Behavioral effects and anatomic correlates after brain injury: a progesterone dose-response study. Pharmacol Biochem Behav (2003) 1.37
Uncertainty in the translation of preclinical experiments to clinical trials. Why do most phase III clinical trials fail? Curr Gene Ther (2009) 1.33
Progesterone's role in neuroprotection, a review of the evidence. Brain Res (2013) 1.31
Measuring functional and quality of life outcomes following major head injury: common scales and checklists. Injury (2010) 1.29
Outcome measures for traumatic brain injury. Clin Neurol Neurosurg (2011) 1.25
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Progesterone as a neuroprotective factor in traumatic and ischemic brain injury. Prog Brain Res (2009) 1.16
Large between-center differences in outcome after moderate and severe traumatic brain injury in the international mission on prognosis and clinical trial design in traumatic brain injury (IMPACT) study. Neurosurgery (2011) 1.13
Why do phase III trials of promising heart failure drugs often fail? The contribution of "regression to the truth". J Card Fail (2003) 1.10
Progesterone with vitamin D affords better neuroprotection against excitotoxicity in cultured cortical neurons than progesterone alone. Mol Med (2009) 1.08
Sex differences in neuropsychological function and post-concussion symptoms of concussed collegiate athletes. Neurosurgery (2007) 1.05
Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons. J Steroid Biochem Mol Biol (2005) 1.05
Progesterone increases circulating endothelial progenitor cells and induces neural regeneration after traumatic brain injury in aged rats. J Neurotrauma (2011) 1.01
Progesterone treatment normalizes the levels of cell proliferation and cell death in the dentate gyrus of the hippocampus after traumatic brain injury. Exp Neurol (2011) 1.01
Steroid synthesis and metabolism in the nervous system: trophic and protective effects. J Neurocytol (2001) 1.00
Effects of progesterone on neurologic and morphologic outcome following diffuse traumatic brain injury in rats. Exp Neurol (2007) 0.99
Progesterone attenuates hemorrhagic transformation after delayed tPA treatment in an experimental model of stroke in rats: involvement of the VEGF-MMP pathway. J Cereb Blood Flow Metab (2013) 0.97
The long-term effects of sports concussion on retired Australian football players: a study using transcranial magnetic stimulation. J Neurotrauma (2014) 0.96
Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity. Steroids (2011) 0.95
Effects of Glasgow Outcome Scale misclassification on traumatic brain injury clinical trials. J Neurotrauma (2008) 0.95
Progesterone attenuates cerebral edema in neonatal rats with hypoxic-ischemic brain damage by inhibiting the expression of matrix metalloproteinase-9 and aquaporin-4. Exp Ther Med (2013) 0.95
Neuroprotective effects of dihydroprogesterone and progesterone in an experimental model of nerve crush injury. Neuroscience (2008) 0.95
Progress in developing common data elements for traumatic brain injury research: version two--the end of the beginning. J Neurotrauma (2013) 0.95
Progesterone and Nestorone facilitate axon remyelination: a role for progesterone receptors. Endocrinology (2011) 0.94
The effect of progesterone dose on gene expression after traumatic brain injury. J Neurotrauma (2011) 0.94
Measuring outcome in traumatic brain injury treatment trials: recommendations from the traumatic brain injury clinical trials network. J Head Trauma Rehabil (2010) 0.94
Multiple sclerosis: neuroprotective alliance of estrogen-progesterone and gender. Front Neuroendocrinol (2012) 0.92
TBI surveillance using the common data elements for traumatic brain injury: a population study. Int J Emerg Med (2013) 0.92
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Effects of progesterone on intestinal inflammatory response, mucosa structure alterations, and apoptosis following traumatic brain injury in male rats. J Surg Res (2007) 0.90
Differential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesis. Endocrinology (2011) 0.89
Progesterone and allopregnanolone in the central nervous system: response to injury and implication for neuroprotection. J Steroid Biochem Mol Biol (2014) 0.89
Understanding history, and not repeating it. Neuroprotection for acute ischemic stroke: from review to preview. Clin Neurol Neurosurg (2014) 0.89
Progesterone protects blood-brain barrier function and improves neurological outcome following traumatic brain injury in rats. Exp Ther Med (2014) 0.88
Progesterone antagonizes the permissive action of estradiol on tumor necrosis factor-alpha-induced apoptosis of anterior pituitary cells. Endocrinology (2004) 0.87
Efficacy of progesterone following a moderate unilateral cortical contusion injury. J Neurotrauma (2008) 0.87
Mild traumatic brain injury. Handb Clin Neurol (2015) 0.86
Progesterone, BDNF and neuroprotection in the injured CNS. Int J Neurosci (2009) 0.86
Cerebrospinal fluid cortisol and progesterone profiles and outcomes prognostication after severe traumatic brain injury. J Neurotrauma (2014) 0.86
Progesterone reduces secondary damage, preserves white matter, and improves locomotor outcome after spinal cord contusion. J Neurotrauma (2014) 0.86
Pediatric traumatic brain injury in 2012: the year with new guidelines and common data elements. Crit Care Clin (2013) 0.85
Recent findings on neuroprotection against excitotoxicity in the hippocampus of female rats. J Neuroendocrinol (2011) 0.85
Neuroprotective effects of progesterone in traumatic brain injury: blunted in vivo neutrophil activation at the blood-brain barrier. Am J Surg (2013) 0.84
Allopregnanolone and neuroinflammation: a focus on multiple sclerosis. Front Cell Neurosci (2014) 0.84
Why are there no good treatments for diabetic neuropathy? Lancet Diabetes Endocrinol (2014) 0.84
Progesterone for traumatic brain injury--resisting the sirens' song. N Engl J Med (2014) 0.84
TLR4-mediated brain inflammation halts neurogenesis: impact of hormonal replacement therapy. Front Cell Neurosci (2014) 0.83
Progesterone, compared to medroxyprogesterone acetate, to C57BL/6, but not 5α-reductase mutant, mice enhances object recognition and placement memory and is associated with higher BDNF levels in the hippocampus and cortex. Neurosci Lett (2013) 0.83
Delayed progesterone treatment reduces brain infarction and improves functional outcomes after ischemic stroke: a time-window study in middle-aged rats. J Cereb Blood Flow Metab (2013) 0.82
Activation of voltage-gated Na⁺ and Ca²⁺ channels is required for glutamate release from retinal glial cells implicated in cell volume regulation. Neuroscience (2011) 0.82
Traumatic brain injury in 2014. Progress, failures and new approaches for TBI research. Nat Rev Neurol (2015) 0.81
Improving the translation of animal ischemic stroke studies to humans. Metab Brain Dis (2014) 0.81
The neuropathology of traumatic brain injury. Handb Clin Neurol (2015) 0.81
Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia. PLoS One (2014) 0.81
Does the sliding dichotomy result in higher powered clinical trials for stroke and traumatic brain injury research? Clin Trials (2012) 0.80
Biomarkers as outcome predictors in subarachnoid hemorrhage--a systematic review. Biomarkers (2014) 0.80
Effects of chronic oestradiol, progesterone and medroxyprogesterone acetate on hippocampal neurogenesis and adrenal mass in adult female rats. J Neuroendocrinol (2014) 0.80
Progesterone attenuates aquaporin-4 expression in an astrocyte model of ischemia/reperfusion. Neurochem Res (2014) 0.80
Evaluating the translational potential of progesterone treatment following transient cerebral ischaemia in male mice. BMC Neurosci (2014) 0.79
Progesterone blocks multiple routes of ion flux. Mol Cell Neurosci (2011) 0.79
New considerations in the design of clinical trials for traumatic brain injury. Clin Investig (Lond) (2012) 0.79
Improvement of neuronal bioenergetics by neurosteroids: implications for age-related neurodegenerative disorders. Biochim Biophys Acta (2014) 0.79
Allopregnanolone and its precursor progesterone do not reduce injury after experimental stroke in hypertensive rats - role of postoperative temperature regulation? PLoS One (2014) 0.78
Cerebrolysin Asian Pacific trial in acute brain injury and neurorecovery: design and methods. J Neurotrauma (2015) 0.77
Efficacy of the selective progesterone receptor agonist Nestorone for chronic experimental autoimmune encephalomyelitis. J Neuroimmunol (2014) 0.77
Progesterone and allopregnanolone improves stroke outcome in male mice via distinct mechanisms but neither promotes neurogenesis. J Neurochem (2014) 0.77
Metabolic alteration of neuroactive steroids and protective effect of progesterone in Alzheimer's disease-like rats. Neural Regen Res (2013) 0.76
Assessing patient outcomes: pearls for clinical practice and research. Injury (2010) 0.76
Impact of GOS misclassification on ordinal outcome analysis of traumatic brain injury clinical trials. J Neurotrauma (2011) 0.76
Progesterone in transient ischemic stroke: a dose-response study. Psychopharmacology (Berl) (2014) 0.76
Progesterone attenuates experimental subarachnoid hemorrhage-induced vasospasm by upregulation of endothelial nitric oxide synthase via Akt signaling pathway. Biomed Res Int (2014) 0.76
Comparative study of outcome measures and analysis methods for traumatic brain injury trials. J Neurotrauma (2015) 0.76